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Positively Charged Water as a Tumor Growth Stimulator

Received: 1 August 2023     Accepted: 16 August 2023     Published: 28 August 2023
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Abstract

Previously, it was shown that positively charged water is able to hydrate both salts and biopolymers, while negatively charged water is not able to hydrate them. Reflections on the biological significance of this dependence made it possible to assume that cells are able to accumulate predominantly positively charged water and that it is this accumulation that stimulates both cell proliferation and the growth of tumors, including cancers; accordingly, it was proposed to use negatively charged water to stop both cell division and tumor growth. Over time, it became clear that this hypothesis was proposed without taking into account the peculiarities of the interaction of electrified waters with fats. This understanding initiated additional research, which proved to be very productive. In particular, such studies made it possible to establish that positively charged water is attracted to oils and is able to form stable emulsions with them, in contrast to negatively charged water, which does not interact with oils and does not form stable emulsions with them. Thus, the discovered shortcoming of the proposed hypothesis was eliminated. This, in turn, gave additional grounds for re-proposing negatively charged water as an antitumor agent.

Published in Biomedical Sciences (Volume 9, Issue 3)
DOI 10.11648/j.bs.20230903.13
Page(s) 64-72
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2023. Published by Science Publishing Group

Keywords

Cancer, Cell Proliferation, Emulsification, Geopathic Zones

References
[1] Pivovarenko Y: ±Water: Demonstration of water properties, depending on its electrical potential. World Journal of Applied Physics. 2018; 3 (1): 13-18.
[2] Pivovarenko Y: Electrified Water as a Regulator of Cell Proliferation. Journal of Oncology Research. 2021; 3 (1): 1-10.
[3] Nekrasov BV. Bases of general chemistry, 1 1974. Moscow: Chemistry. In Russian.
[4] Kuhling H. Handbook of Physics. 1983. NY: Wiley.
[5] Purcell E. Electricity and Magnetism in BPC, 2. 1984. NY: McGraw-Hill Science.
[6] Sackmann E. Biological membranes architecture and functions; Chapter 1 in: Handbook of Biological Physics, 1. 1995. Netherlands: Elsevier Science BV.
[7] Watson H. Biological membranes. Essays of Biochemistry. 2015; 59: 43-69.
[8] Lowry TH. Richardson KS. Mechanism and Theory in Organic Chemistry, 3rd Edition. 1987. NY: Harper & Row.
[9] Klein D. Organic Chemistry, 3rd Edition. 2016. NY: Wiley.
[10] Jirgensons B, Straumanis ME. A Short Textbook of Colloid Chemistry, 2nd Edition. 1962. Oxford: Pergamon Press.
[11] Bird KS. Handbook of Surface and Colloid Chemistry, 4th Edition. 2020. USA, Boca Raton (Florida): CRC Press.
[12] Lane N. Why Are Cells Powered by Proton Gradients? Nature Education. 2010; 3 (9): 18.
[13] Lane N, Allen JF, Martin W. How did LUCA make a living? Chemiosmosis in the origin of life. Bioassays. 2010; 32: 271-280.
[14] Malins DC. Precancerous diagnostics for breast cancer by studying free-radical damage to DNA. Optical Engineering Reports. 1995; 135: 1-3.
[15] Pivovarenko Y. An Alternative Strategy in Cancer Chemotherapy, Aimed Not at Killing Cancer Cells, but the Recovery of Their DNA, Modified by Active Oxygen. Biomedical Sciences. 2017; 3 (5): 94-98.
[16] Terentyeva Y, Pivovarenko Y. UV Absorbance of Lymphocytes. European Journal of Advanced Research in Biological and Life Sciences. 2015; 3 (4): 20-24.
[17] Pivovarenko Y. Biochemical and Physiological Basis for Treating Hydrogen Gas as a Medicine. European Journal of Preventive Medicine. 2019; 7 (6): 100-107.
[18] Crawford F. Waves in BPC, 3. 1968. NY: McGraw-Hill.
[19] Krasnogorskaja NV. Electromagnetic field in the earth’s atmosphere and their biological significance, 1. 1984. Moscow: Nauka.
[20] Feynman R, Leighton R, Sands M. FLP, 3. 1971. Massachusetts: Addison Wesley Publishing Company.
[21] Pivovarenko Y. The Use of Electromagnetic Forces of the Earth in Manual and Physio Therapy. Journal of Human Physiology. 2020; 2 (1): 10-15.
[22] Reif F. BPC, 5. 1967. NY: McGraw-Hill Book Company.
[23] Fenn JB. Engines, energy and entropy. 1982. New York and San Francisco: WH Freeman and Company.
[24] Pivovarenko Y. The Gulf Stream and the Californian Current as Factors Affecting the Behavior and Health of Americans. Journal of Human Physiology. 2021; 3 (2): 51-56.
[25] Dubrov AP. Geopathic Zones and Oncological Diseases. Theses of 16th Seminar of BDA, Druskininkai (Lithuania). 2008: 42-44.
[26] Tong ES, Kong CK. An Overview of Impact of Geopathic Stress on Environment and Human Health. Progress in Drug Discovery and Biomedical Science. 2021: 1-25.
[27] Pivovarenko Y. Earth's Electromagnetic Forces and Their Participation in the Creation of Tornadoes. American Journal of Electromagnetics and Applications. 2019; 7 (1): 8-12.
[28] Chen J, Mu F, Lu T et al. Brain Metastases Completely Disappear in Non-Small Cell Lung Cancer Using Hydrogen Gas Inhalation: A Case Report. OncoTargets and Therapy. 2019; 12: 11145–11151.
[29] Chen JB, Kong XF, Lv YY et al. “Real world survey” of hydrogen-controlled cancer: a follow-up report of 82 advanced cancer patients. Medical Gas Research. 2019; 9 (3): 115-121.
[30] Noor MNZM, Alauddin AS, Wong YH et al. A Systematic Review of Molecular Hydrogen Therapy in Cancer Management. Asian Pacific Journal of Cancer Prevention. 2023; 24 (1): 37-47.
[31] Melkonian EA, Schury MP. Biochemistry. Anaerobic Glycolysis. 2022. USA, Treasure Island (Florida): StatPearls Publishing.
[32] Schulz H. Oxidation of fatty acids in eukaryotes in: Biochemistry of Lipids, Lipoproteins and Membranes, 5th Edition. 2008. Netherlands: Elsevier.
[33] Sajnani K, Islam F, Smith RA et al. Genetic alterations in Krebs cycle and its impact on cancer pathogenesis. Biochimie. 2017; 135: 164-172.
[34] Eniafe J, Jiang S. The functional roles of TCA cycle metabolites in cancer. Oncogene. 2021; 40: 3351-3363.
[35] Terman M. Terman J, Ross D. A Controlled Trial of Timed Bright Light and Negative Air Ionization for Treatment of Winter Depression. Archives of General Psychiatry. 1998; 55 (10), 875-882.
[36] Terman M. Terman JS. Controlled Trial of Naturalistic Dawn Simulation and Negative Air Ionization for Seasonal Affective Disorder. American Journal of Psychiatry, 2006; 163 (12), 2126-33.
[37] Pivovarenko Y. Negative Electrization of Air as a Means of Counteracting Airborne Viral Infections. European Journal of Preventive Medicine. 2022; 10 (1): 34-39.
[38] Wang C-C, Lin S-Y, Lai Y-H et al. Dimethyl sulfoxide promotes the multiple functions of the tumor suppressor HLJ1 through activator protein–1 activation in NSCLC cells. PLoS ONE. 2012; 7 (4).
[39] Villarroel A, Duff A, Hu T. DMSO inhibits human cancer cells and downregulates the expression of cdk2 and cyclin A. The FASEB journal. 2020; 34 (S1): 1.
[40] Eberhardt MK, Colina R. The reaction of OH radicals with dimethyl sulfoxide. A comparative study of Fenton’s reagent and the radiolysis of aqueous dimethyl sulfoxide solutions. The Journal of Organic Chemistry, 1988; 53: 1071-1074.
[41] Babbs CF, Griffin DW. Scatchard analysis of methane sulfinic acid production from dimethyl sulfoxide: a method to quantify hydroxyl radical formation in physiological systems. Free Radical Biology & Medicine. 1989; 6: 493-503.
[42] Pelizzola M, Ecker J. The DNA methylpme. FEBS Letters. 2011; 585: 1994-2000.
[43] Lee AY, Levine MN, Baker RI, et al. Low-molecular-weight heparin versus a coumarin for the prevention of recurrent venous thromboembolism in patients with cancer. The New England Journal of Medicine. 2003; 349: 146-153.
[44] Lee AY, Peterson EA. Treatment of cancer-associated thrombosis. Blood. 2013; 122: 2310-2317.
[45] Raskob GE, van Es N, Verhamme P et al. Edoxaban for the Treatment of Cancer-Associated Venous Thromboembolism. The New England Journal of Medicine. 2018; 378: 615-624.
[46] Fune B, Fune BC. Mechanisms of Thrombus Formation. The New England Journal of Medicine. 2008; 359: 938-949.
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  • APA Style

    Yuri Pivovarenko. (2023). Positively Charged Water as a Tumor Growth Stimulator. Biomedical Sciences, 9(3), 64-72. https://doi.org/10.11648/j.bs.20230903.13

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    ACS Style

    Yuri Pivovarenko. Positively Charged Water as a Tumor Growth Stimulator. Biomed. Sci. 2023, 9(3), 64-72. doi: 10.11648/j.bs.20230903.13

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    AMA Style

    Yuri Pivovarenko. Positively Charged Water as a Tumor Growth Stimulator. Biomed Sci. 2023;9(3):64-72. doi: 10.11648/j.bs.20230903.13

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  • @article{10.11648/j.bs.20230903.13,
      author = {Yuri Pivovarenko},
      title = {Positively Charged Water as a Tumor Growth Stimulator},
      journal = {Biomedical Sciences},
      volume = {9},
      number = {3},
      pages = {64-72},
      doi = {10.11648/j.bs.20230903.13},
      url = {https://doi.org/10.11648/j.bs.20230903.13},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.bs.20230903.13},
      abstract = {Previously, it was shown that positively charged water is able to hydrate both salts and biopolymers, while negatively charged water is not able to hydrate them. Reflections on the biological significance of this dependence made it possible to assume that cells are able to accumulate predominantly positively charged water and that it is this accumulation that stimulates both cell proliferation and the growth of tumors, including cancers; accordingly, it was proposed to use negatively charged water to stop both cell division and tumor growth. Over time, it became clear that this hypothesis was proposed without taking into account the peculiarities of the interaction of electrified waters with fats. This understanding initiated additional research, which proved to be very productive. In particular, such studies made it possible to establish that positively charged water is attracted to oils and is able to form stable emulsions with them, in contrast to negatively charged water, which does not interact with oils and does not form stable emulsions with them. Thus, the discovered shortcoming of the proposed hypothesis was eliminated. This, in turn, gave additional grounds for re-proposing negatively charged water as an antitumor agent.},
     year = {2023}
    }
    

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  • TY  - JOUR
    T1  - Positively Charged Water as a Tumor Growth Stimulator
    AU  - Yuri Pivovarenko
    Y1  - 2023/08/28
    PY  - 2023
    N1  - https://doi.org/10.11648/j.bs.20230903.13
    DO  - 10.11648/j.bs.20230903.13
    T2  - Biomedical Sciences
    JF  - Biomedical Sciences
    JO  - Biomedical Sciences
    SP  - 64
    EP  - 72
    PB  - Science Publishing Group
    SN  - 2575-3932
    UR  - https://doi.org/10.11648/j.bs.20230903.13
    AB  - Previously, it was shown that positively charged water is able to hydrate both salts and biopolymers, while negatively charged water is not able to hydrate them. Reflections on the biological significance of this dependence made it possible to assume that cells are able to accumulate predominantly positively charged water and that it is this accumulation that stimulates both cell proliferation and the growth of tumors, including cancers; accordingly, it was proposed to use negatively charged water to stop both cell division and tumor growth. Over time, it became clear that this hypothesis was proposed without taking into account the peculiarities of the interaction of electrified waters with fats. This understanding initiated additional research, which proved to be very productive. In particular, such studies made it possible to establish that positively charged water is attracted to oils and is able to form stable emulsions with them, in contrast to negatively charged water, which does not interact with oils and does not form stable emulsions with them. Thus, the discovered shortcoming of the proposed hypothesis was eliminated. This, in turn, gave additional grounds for re-proposing negatively charged water as an antitumor agent.
    VL  - 9
    IS  - 3
    ER  - 

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Author Information
  • Research and Training Centre ‘Physical and Chemical Materials Science’ Under Kyiv Taras Shevchenko University and NAS of Ukraine, Kyiv, Ukraine

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