Currently, malaria rapid diagnostic tests (mRDTs) are increasingly used for the diagnosis of malaria, particularly in communities where microscopy-based diagnosis is not practical. However, the diagnostic accuracy of mRDTs performed by community health workers (CHWs) remains unknown. This study was conducted to determine the accuracy of mRDT results performed by CHWs in Ngoma district, eastern province of Rwanda. This was a cross sectional prospective study. A total of 420 blood samples of patients self-reported to CHWs for malaria diagnosis were collected and analyzed by CHWs using mRDT, and quality control tests were performed by using microscopy as a reference test. The study was conducted from 22 April to 08 July 2021. Among the 420 patients, 234 (55.71%) were females, and 186 (44.29%) were males. Malaria test positivity was 2.62% by using mRDT and 1.67% by using microscopic tests. The sensitivity and specificity of mRDT were 85.71% and 98.78%, respectively. The negative predictive value, positive predictive value and accuracy of mRDTs were 99.75%, 54.54% and 98.57%, respectively. The sensitivity of mRDT was below the WHO recommended sensitivity (>95%), although the specificity (98.78%) was within the WHO recommended specificity (>=90). There was substantial agreement between the mRDT and malaria microscopic test results, k=0.642. mRDTs continue to be an appropriate choice for malaria diagnosis in the absence of microscopy.
| Published in | Central African Journal of Public Health (Volume 8, Issue 1) |
| DOI | 10.11648/j.cajph.20220801.12 |
| Page(s) | 6-12 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2022. Published by Science Publishing Group |
Quality Assurance, Malaria Rapid Diagnostic Test, Microscopy, Sensitivity, Specificity, Accuracy
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APA Style
Metuschelah Habimana, Vedaste Ndahindwa, Stella Matutina Umuhoza, Jared Omolo, Schifra Uwamungu, et al. (2022). Quality Assurance Assessment for Malaria Rapid Diagnostic Test in Ngoma District, Eastern Province of Rwanda: A Cross-sectional Prospective Study. Central African Journal of Public Health, 8(1), 6-12. https://doi.org/10.11648/j.cajph.20220801.12
ACS Style
Metuschelah Habimana; Vedaste Ndahindwa; Stella Matutina Umuhoza; Jared Omolo; Schifra Uwamungu, et al. Quality Assurance Assessment for Malaria Rapid Diagnostic Test in Ngoma District, Eastern Province of Rwanda: A Cross-sectional Prospective Study. Cent. Afr. J. Public Health 2022, 8(1), 6-12. doi: 10.11648/j.cajph.20220801.12
AMA Style
Metuschelah Habimana, Vedaste Ndahindwa, Stella Matutina Umuhoza, Jared Omolo, Schifra Uwamungu, et al. Quality Assurance Assessment for Malaria Rapid Diagnostic Test in Ngoma District, Eastern Province of Rwanda: A Cross-sectional Prospective Study. Cent Afr J Public Health. 2022;8(1):6-12. doi: 10.11648/j.cajph.20220801.12
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Download@article{10.11648/j.cajph.20220801.12,
author = {Metuschelah Habimana and Vedaste Ndahindwa and Stella Matutina Umuhoza and Jared Omolo and Schifra Uwamungu and Naomi Wangui Lucchi and James Humuza},
title = {Quality Assurance Assessment for Malaria Rapid Diagnostic Test in Ngoma District, Eastern Province of Rwanda: A Cross-sectional Prospective Study},
journal = {Central African Journal of Public Health},
volume = {8},
number = {1},
pages = {6-12},
doi = {10.11648/j.cajph.20220801.12},
url = {https://doi.org/10.11648/j.cajph.20220801.12},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cajph.20220801.12},
abstract = {Currently, malaria rapid diagnostic tests (mRDTs) are increasingly used for the diagnosis of malaria, particularly in communities where microscopy-based diagnosis is not practical. However, the diagnostic accuracy of mRDTs performed by community health workers (CHWs) remains unknown. This study was conducted to determine the accuracy of mRDT results performed by CHWs in Ngoma district, eastern province of Rwanda. This was a cross sectional prospective study. A total of 420 blood samples of patients self-reported to CHWs for malaria diagnosis were collected and analyzed by CHWs using mRDT, and quality control tests were performed by using microscopy as a reference test. The study was conducted from 22 April to 08 July 2021. Among the 420 patients, 234 (55.71%) were females, and 186 (44.29%) were males. Malaria test positivity was 2.62% by using mRDT and 1.67% by using microscopic tests. The sensitivity and specificity of mRDT were 85.71% and 98.78%, respectively. The negative predictive value, positive predictive value and accuracy of mRDTs were 99.75%, 54.54% and 98.57%, respectively. The sensitivity of mRDT was below the WHO recommended sensitivity (>95%), although the specificity (98.78%) was within the WHO recommended specificity (>=90). There was substantial agreement between the mRDT and malaria microscopic test results, k=0.642. mRDTs continue to be an appropriate choice for malaria diagnosis in the absence of microscopy.},
year = {2022}
}
TY - JOUR T1 - Quality Assurance Assessment for Malaria Rapid Diagnostic Test in Ngoma District, Eastern Province of Rwanda: A Cross-sectional Prospective Study AU - Metuschelah Habimana AU - Vedaste Ndahindwa AU - Stella Matutina Umuhoza AU - Jared Omolo AU - Schifra Uwamungu AU - Naomi Wangui Lucchi AU - James Humuza Y1 - 2022/02/25 PY - 2022 N1 - https://doi.org/10.11648/j.cajph.20220801.12 DO - 10.11648/j.cajph.20220801.12 T2 - Central African Journal of Public Health JF - Central African Journal of Public Health JO - Central African Journal of Public Health SP - 6 EP - 12 PB - Science Publishing Group SN - 2575-5781 UR - https://doi.org/10.11648/j.cajph.20220801.12 AB - Currently, malaria rapid diagnostic tests (mRDTs) are increasingly used for the diagnosis of malaria, particularly in communities where microscopy-based diagnosis is not practical. However, the diagnostic accuracy of mRDTs performed by community health workers (CHWs) remains unknown. This study was conducted to determine the accuracy of mRDT results performed by CHWs in Ngoma district, eastern province of Rwanda. This was a cross sectional prospective study. A total of 420 blood samples of patients self-reported to CHWs for malaria diagnosis were collected and analyzed by CHWs using mRDT, and quality control tests were performed by using microscopy as a reference test. The study was conducted from 22 April to 08 July 2021. Among the 420 patients, 234 (55.71%) were females, and 186 (44.29%) were males. Malaria test positivity was 2.62% by using mRDT and 1.67% by using microscopic tests. The sensitivity and specificity of mRDT were 85.71% and 98.78%, respectively. The negative predictive value, positive predictive value and accuracy of mRDTs were 99.75%, 54.54% and 98.57%, respectively. The sensitivity of mRDT was below the WHO recommended sensitivity (>95%), although the specificity (98.78%) was within the WHO recommended specificity (>=90). There was substantial agreement between the mRDT and malaria microscopic test results, k=0.642. mRDTs continue to be an appropriate choice for malaria diagnosis in the absence of microscopy. VL - 8 IS - 1 ER -
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