From times immemorial, medicinal plants have been used to relieve and cure human diseases. Currently, the control of bacterial infections is becoming complex due to the concern of antibiotic resistance, which has been a significant global health problem. The aim of this work was to determine the phytochemical composition as well as to assess the bioactivities of Phytolacca dodecandra leaf extracts. The leaves of P. dodecandra were collected in January 2017 at Yakoma city, Nord-Ubangi, DRC. Three bacterial strains namely Staphylococcus aureus ATCC 25923, Escherichia coli ATCC 8739 and Pseudomonas aeroginosa ATCC 9027 were used for the assessment of the antibacterial activity. The qualitative and quantitative phytochemical screening were used for compound identification. The antioxidant activity was assessed using ABTS and DPPH scavenging tests while the antibacterial activity was performed using the diffusion method. The findings show that leaves of this plant are rich in flavonoids, anthocyanins, terpenoids and irrioids. The inhibitory concentration 50 (IC50) values obtained in the ATBS test are lower than those of the DPPH test. The antibacterial activity of this plant was low against the three strains used. These in vitro findings show that medicinal plants have very important biological properties that have many applications in various fields such as medicine, pharmacy and agriculture.
| Published in | International Journal of Biomedical Engineering and Clinical Science (Volume 5, Issue 3) |
| DOI | 10.11648/j.ijbecs.20190503.11 |
| Page(s) | 31-39 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2019. Published by Science Publishing Group |
Phytolacca dodecandra, Antibiotic Resistance, Bioactivity, Yakoma, DRC
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APA Style
Jeff Bekomo Iteku, Ornella Mbayi, Gedeon Ngiala Bongo, Paulin Kapepula Mutwale, Jose Mulwahali Wambale, et al. (2019). Phytochemical Analysis and Assessment of Antibacterial and Antioxidant Activities of Phytolacca dodecandra L. Herit Leaf Extracts (Phytolaccaceae). International Journal of Biomedical Engineering and Clinical Science, 5(3), 31-39. https://doi.org/10.11648/j.ijbecs.20190503.11
ACS Style
Jeff Bekomo Iteku; Ornella Mbayi; Gedeon Ngiala Bongo; Paulin Kapepula Mutwale; Jose Mulwahali Wambale, et al. Phytochemical Analysis and Assessment of Antibacterial and Antioxidant Activities of Phytolacca dodecandra L. Herit Leaf Extracts (Phytolaccaceae). Int. J. Biomed. Eng. Clin. Sci. 2019, 5(3), 31-39. doi: 10.11648/j.ijbecs.20190503.11
AMA Style
Jeff Bekomo Iteku, Ornella Mbayi, Gedeon Ngiala Bongo, Paulin Kapepula Mutwale, Jose Mulwahali Wambale, et al. Phytochemical Analysis and Assessment of Antibacterial and Antioxidant Activities of Phytolacca dodecandra L. Herit Leaf Extracts (Phytolaccaceae). Int J Biomed Eng Clin Sci. 2019;5(3):31-39. doi: 10.11648/j.ijbecs.20190503.11
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Download@article{10.11648/j.ijbecs.20190503.11,
author = {Jeff Bekomo Iteku and Ornella Mbayi and Gedeon Ngiala Bongo and Paulin Kapepula Mutwale and Jose Mulwahali Wambale and Emmanuel Lengbiye and Clement Liyongo Inkoto and Samy Ngunde Ngunde and Koto-te-Nyiwa Ngbolua},
title = {Phytochemical Analysis and Assessment of Antibacterial and Antioxidant Activities of Phytolacca dodecandra L. Herit Leaf Extracts (Phytolaccaceae)},
journal = {International Journal of Biomedical Engineering and Clinical Science},
volume = {5},
number = {3},
pages = {31-39},
doi = {10.11648/j.ijbecs.20190503.11},
url = {https://doi.org/10.11648/j.ijbecs.20190503.11},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijbecs.20190503.11},
abstract = {From times immemorial, medicinal plants have been used to relieve and cure human diseases. Currently, the control of bacterial infections is becoming complex due to the concern of antibiotic resistance, which has been a significant global health problem. The aim of this work was to determine the phytochemical composition as well as to assess the bioactivities of Phytolacca dodecandra leaf extracts. The leaves of P. dodecandra were collected in January 2017 at Yakoma city, Nord-Ubangi, DRC. Three bacterial strains namely Staphylococcus aureus ATCC 25923, Escherichia coli ATCC 8739 and Pseudomonas aeroginosa ATCC 9027 were used for the assessment of the antibacterial activity. The qualitative and quantitative phytochemical screening were used for compound identification. The antioxidant activity was assessed using ABTS and DPPH scavenging tests while the antibacterial activity was performed using the diffusion method. The findings show that leaves of this plant are rich in flavonoids, anthocyanins, terpenoids and irrioids. The inhibitory concentration 50 (IC50) values obtained in the ATBS test are lower than those of the DPPH test. The antibacterial activity of this plant was low against the three strains used. These in vitro findings show that medicinal plants have very important biological properties that have many applications in various fields such as medicine, pharmacy and agriculture.},
year = {2019}
}
TY - JOUR T1 - Phytochemical Analysis and Assessment of Antibacterial and Antioxidant Activities of Phytolacca dodecandra L. Herit Leaf Extracts (Phytolaccaceae) AU - Jeff Bekomo Iteku AU - Ornella Mbayi AU - Gedeon Ngiala Bongo AU - Paulin Kapepula Mutwale AU - Jose Mulwahali Wambale AU - Emmanuel Lengbiye AU - Clement Liyongo Inkoto AU - Samy Ngunde Ngunde AU - Koto-te-Nyiwa Ngbolua Y1 - 2019/10/11 PY - 2019 N1 - https://doi.org/10.11648/j.ijbecs.20190503.11 DO - 10.11648/j.ijbecs.20190503.11 T2 - International Journal of Biomedical Engineering and Clinical Science JF - International Journal of Biomedical Engineering and Clinical Science JO - International Journal of Biomedical Engineering and Clinical Science SP - 31 EP - 39 PB - Science Publishing Group SN - 2472-1301 UR - https://doi.org/10.11648/j.ijbecs.20190503.11 AB - From times immemorial, medicinal plants have been used to relieve and cure human diseases. Currently, the control of bacterial infections is becoming complex due to the concern of antibiotic resistance, which has been a significant global health problem. The aim of this work was to determine the phytochemical composition as well as to assess the bioactivities of Phytolacca dodecandra leaf extracts. The leaves of P. dodecandra were collected in January 2017 at Yakoma city, Nord-Ubangi, DRC. Three bacterial strains namely Staphylococcus aureus ATCC 25923, Escherichia coli ATCC 8739 and Pseudomonas aeroginosa ATCC 9027 were used for the assessment of the antibacterial activity. The qualitative and quantitative phytochemical screening were used for compound identification. The antioxidant activity was assessed using ABTS and DPPH scavenging tests while the antibacterial activity was performed using the diffusion method. The findings show that leaves of this plant are rich in flavonoids, anthocyanins, terpenoids and irrioids. The inhibitory concentration 50 (IC50) values obtained in the ATBS test are lower than those of the DPPH test. The antibacterial activity of this plant was low against the three strains used. These in vitro findings show that medicinal plants have very important biological properties that have many applications in various fields such as medicine, pharmacy and agriculture. VL - 5 IS - 3 ER -
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