The present comprehensive review was conducted in the Department of Biotechnology and Genetic Engineering of Islamic University, Kushtia, to pile up update ethno-pharmacological information of Lippia alba (Mill) that is available in different scientific literatures. L. alba, belongs to the family of verbenaceae, found everywhere in Bangladesh and it is commonly used in folk medicine to treat gastric illnesses, diarrhea, fever, asthma, malaria, and inflammation. Phytochemical analysis showed that the crude extract of fresh leaves consists of some valuable essential oils and that is found to be effective against bacteria, fungus, protozoa, and virus. The present paper also covers the taxonomy, morphology, monograph, usable parts, and distribution of this valuable medicinal plant.
Published in | International Journal of Biomedical Materials Research (Volume 1, Issue 1) |
DOI | 10.11648/j.ijbmr.20130101.13 |
Page(s) | 14-20 |
Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
Copyright |
Copyright © The Author(s), 2013. Published by Science Publishing Group |
Lippia Alba, Ethno-Pharmacological, Folk Medicine, Phytochemical Analysis
[1] | Heinrich M, Barnes J, Gibbons S and Williamson EM. Fundamental of Pharmacognosy and Phytotherapy. Churchill Livingstone, Edinbrugh. 2004. |
[2] | Rios JL and Recio MC. Medicinal plants and antimicrobial activity. J. Ethnopharmacol. 2005; 100: 80-84. |
[3] | Jose GSF, Janaina GSM, Antonio MS, Ademario MG, Maria NCP and Haroudo SX. Antimicrobial activity and phytochemical profi le from the roots of Lippia alba (Mill.) N.E. Brown. Brazilian J. Pharmacog. 2006; 16(4): 506-509. |
[4] | Mamun-or-Rashid ANM, Islam MR and Dash BK. In vitro Antibacterial Effect of Bushy Matgrass (Lippia alba Mill.) Extracts. Res. J. Med. Plant. 2012; 6: 334-340. |
[5] | Robard I. Plantes medicinales doutre-mer et pharmacopees: aspects juridiques, economiques et culturels. Phytotherapie-De la Recherche a la Pratique. 2003; 1: 16-21. |
[6] | Stashenko EE, Jaramillo BE andMartinez JR. Comparison of different extraction methods for the analysis of volatile secondary metabolites of Lippia alba (Mill.) N.E. Brown, grown in Colombia, and evaluation of its in vitro antioxidant activity. J. Chromatography A. 2003; 1025: 93-103. |
[7] | Singh G, Rao GP, Kapoor PS and Singh OP. Chemical constituents and antifungal activity of Lippia alba Mill. leaf essential oil. J. Med. Aro. Plant Sci. 2000; 22: 701-703. |
[8] | Day MD and Mc Andrew TD. The biology and host range of Falconia intermedia (Hemiptera: Miridae), a potential biological control agent for Lantana camara (Verbenaceae) in Australia. Biocon. Sci.Technol. 2003; 13: 13-22. |
[9] | Heinrich M, Rimpler H and Barrera NA. Indigenous phytotherapy of gastrointestinal disorders in a lowland Mixe community (Oaxaca, Mexico) ethnopharmacologic evaluation. J. Ethnopharmacol. 1992; 36: 63-80. |
[10] | Caceres AL, Fletes L, Aguilar O, Ramires L, Figueroa AM, Taracena BE and Samayoa. Plants used in Guatemala for the treatment of gastrointestinal disorders. 3. Confirmation of activity against enterobacteria of 16 plants. J. Ethnopharmacol. 1993; 38: 31-38. |
[11] | Marisa AN, Gaspar D, Luciana S and Patricia MT. Antibacterial Activity of Lippia alba (Lemon Herb). Latin America J. Pharmacol. 2007; 26(3): 404-406. |
[12] | Pascual M, Slowing EK, Carretero E, Sanchez Mata D, Villar A. J. Ethnopharmacol. 2001; 76: 201-214. |
[13] | Matos FJA. As ervas cidreiras do nordeste do Brasil. Estudo de três quimiotipos de Lippia alba (Mill). N.E.Br- Verbenaceae. Revista Brasileira de Ciências Farmacêuticas 1996; 77: 137-141. |
[14] | Frighetto N, Oliveira JG, Siani AC and Chagas KC. J. Essential Oil Res. 1998; 10: 578-580. |
[15] | Pino A, Luiz AGO, Peres AR, Jorge MR and Baluja R. Revista Cubana de Farmacia. 1997; 30:29-35. |
[16] | Gomes EC, Ming LC, Moreira EA, Miguel OG, Miguel MD, Kerber VA, Conti A and Filho AW. Revista Brasileira de Ciências Farmacêuticas. 1993; 74: 29-32. |
[17] | Craveiro AA, Alencar JW, Matos FJA, Andrade CHS, Machado MIL. Essential oils from Brazilian Verbenaceae genus Lippia. J.Nat. Pro.1981; 44: 598-601. |
[18] | Zoghbi MGB, Andrade EHA, Santos AS, Silva MHL and Maia JGS. Flavour Fragrance J. 1988; 14: 411-414. |
[19] | Dellacassa E, Soler E, Menéndez P and Moyna P. Revista Brasileira de Ciências Farmacêuticas. 1990; 5: 107-108. |
[20] | Senatore F and Rigano D. Essential oil of two Lippia spp. (Verbenaceae) growing wild in Guatemala. Flavour and Fragrance J. 2001; 16: 169-171. |
[21] | Britton NL and Wilson P. Botany of Porto Rico and the Virgin Islands. Scientific Survey of Porto Rico and the Virgin Islands. New York Academy of Sciences, New York. 1926. |
[22] | Tucker AO and Thomas DB. The Encyclopedia of Herbs: A Comprehensive Reference to Herbs of Flavor and Fragrance (2 ed.). Timber Press. 2009. |
[23] | Duke JA. Duke's Handbook of Medicinal Plants of Latin America. CRC Press. 2008: 412-414. |
[24] | Di Stasi LC, Oliveira GP, Carvalhaes MA, Queiroz-Junior M, Tien OS, Kakinami SH and Reis MS. Medicinal plants popularly used in the Brazilian Tropical Atlantic Forest. Fitoterapia. 2002; 73: 69-91. |
[25] | Morton. Atlas of Medicinal Plants of Middle America, vol. I. Springfield, Illinois, USA. 1981: 745-750. |
[26] | Adams CD. Flowering Plants of Jamaica. University of the West Indies, Glasgow University Press, Glasgow. 1972. |
[27] | Fournet J. Flore Illustree des Phanerogames de Guadeloupe et de Martinique (tome 2). CIRAD, Gondwana Editions, Tartane. 2002. |
[28] | Howard RA. Flora of the Lesser Antilles. Arnold Arboretum, Harvard University, Jamaica Plain, Massachussetts. 1989. |
[29] | Terblanche FC, Kornelius G. Essential oil constituents of the genus Lippia (Verbenaceae)-A literature review. J. Essential Oil Res. 1996; 8: 471-485. |
[30] | Rodrigues ACC and Guedes MLS. Utilizac¸ ao de plantas medicinais no Povoado Sapucaia, Cruz das Almas—Bahia. Revista Brasileira de Plantas Medicinais. 2006; 8: 1-7. |
[31] | Pinto EPP, Amorozo MCM, Furlan A. Conhecimento popular sobre plantas medicinais em comunidades rurais de mata atlantica-Itacar´e, BA, Brasil. Acta Botanica Brasilica. 2006; 20: 751-762. |
[32] | Giron LM, Freire V, Alonz A and Caceres A. Ethnobotanical survey of the medicinal flora used by the Caribs of Guatemala. J. Ethnopharmacol. 1991; 34: 173-187. |
[33] | Toscano-Gonzalez JY. Uso tradicional de plantas medicinales en la vereda San Isidro, municipio de San Jose de Pare-Boyaca: un estudio preliminary usando tecnicas cuantitativas. Acta Biologica Colombiana. 2006; 11: 137-146. |
[34] | Oliveira DR, Leitao GG, Santos SS, Bizzo HR, Lopes D, Alviano CS, Alviano DS and Leitao SG. Ethnopharmacological study of two Lippia species from Oriximina, Brazil. J. Ethnopharmacol. 2006; 108: 103-108. |
[35] | Franco EAP, Barros RFM. Uso e diversidade de plantas medicinais no Quilombo Olho Dagua dos Pires, Esperantina Piau. Revista Brasileira de Plantas Medicinais. 2006; 8: 68-88. |
[36] | Vendruscolo GS, Mentz LA. Estudo da concordancia das citac¸ oes de uso e importancia das especies e famılias utilizadas como medicinais pela comunidade do bairro Ponta Grossa, Porto Alegre, RS, Brasil. Acta Botanica Brasilica. 2006; 20: 367-382. |
[37] | Gazzaneo LRS, de Lucena RFP, de Albuquerque UP. Knowledge and use of medicinal plants by local specialists in a region of Atlantic Forest in the state of Pernambuco (Northeastern Brazil). J. Ethnobiol. Ethnomed. 2005 1: 1-8. |
[38] | Pino Alea JA, Ortega Luis AG, Rosado Perez A, Rodriguez Jorge M and Baluja R. Composicion y propiedades antibacterianas del aceite esencial de Lippia alba (Mill.) N.E. Brown. Revista Cubana de Farmacia. 1996: 30: 1-10. |
[39] | Holetz FB, Pessini GL, Sanches NR, Cortez DAG, Nakamura CV and Filho BPD. Screening of some plants used in the brazilian folk medicine for the treatment of infectious diseases. Memorias do Instituto Oswaldo Cruz. 2002; 97: 1027-1031. |
[40] | Aguiar JS. Atividades antimicrobiana, citotoxica, antitumoral e antiinflamatoria de extratos brutos de Lippia alba (Mill.) N.E. Brown. Mestrado em ciencias biologicas, Universidade de Pernambuco. 2006. |
[41] | Sena Filho JG, Melo JGS, Saraiva AM, Gonc¸alves AM, Psiottano MNC and Xavier HS. Antimicrobial activity and phytochemical profile from the roots of Lippia alba (Mill.) N.E. Brown. Revista Brasileira de Farmacognosia. 2006; 16: 506-509. |
[42] | Antoun MD, Ramos Z, Vazques J, Oquendo I, Proctor GR, Gerena L and Franzblau SG. Evaluation of the flora of Puerto Rico for in vitro antiplasmodial and antimycobacterial activities. Phytother. Res. 2001; 15: 638-642. |
[43] | Alanis AD, Calzada F, Cervantes JA, Torres J, Ceballos GM. Antibacterial properties of some plants used in Mexican traditional medicine for the treatment of gastrointestinal disorders. J. Ethnopharmacol. 2005; 100: 153-157. |
[44] | Duarte MCT, Figueira GM, Sartoratto A, Rehder VLG and Delarmelina C. Anti-Candida activity of Brazilian medicinal plants. J. Ethnopharmacol. 2005; 97: 305-311. |
[45] | Abad MJ, Bermejo P, Villar A, Sanchez Palomino S, Carrasco L. Antiviral activity of medicinal plant extracts. Phytother. Res. 1997; 11: 198-202. |
[46] | Ruffa MJ, Wagner ML, Suriano M, Vicente C, Nadinic J, Pampuro S, Salomon H, Campos RH and Cavallaro L. Inhibitory effect of medicinal herbs against RNA and DNA viruses. Antiviral Chem. Chemother. 2004; 15: 153-159. |
[47] | Andrighetti-Frohner CR, Sincero TCM, da Silva AC, Savi LA, Gaido CM, Bettega JMR, Mancini M, de Almeida MTR, Barbosa RA, Farias MR, Barardi CRM and Simoes CMO. Antiviral evaluation of plants from Brazilian atlantic tropical forest. Fitoterapia. 2005; 76: 374-378. |
[48] | Calzada F, Yepez-Mulia L and Aguilar A. In vitro susceptibility of Entamoeba histolytica and Giardia lamblia to plants used in Mexican traditional medicine for the treatment of gastrointestinal disorders. J. Ethnopharmacol. 2006; 108: 367-370. |
[49] | Calzada F, Yepez-Mulia L and Tapia-Contreras A. Effect of Mexican medicinal plant used to treat trichomoniasis on Trichomonas vaginalis trophozoites. J. Ethnopharmacol. 2007; 113: 248-251. |
[50] | Vale TG, Matos FJA, Lima TCM and Viana GSB. Behavioral effects of essential oils from Lippia alba (Mill.) N.E. Brown chemotypes. J. Ethnopharmacol. 1999; 167: 127-133. |
[51] | Vale TG, Furtado EC, Santos JJG and Viana GSB. Central effects of citral, myrcene and limonene, constituents of essential oil chemotypes from Lippia alba (Mill.) N.E. Brown. Phytomed. 2002; 9: 709-714. |
[52] | Zetola M, Lima TCM, Sonaglio D, Gonzalez-Ortega G, Limberge RP, Petrovick PR and Bassani PR. CNS activities of liquid and spray-dried extracts from Lippia alba-Verbenaceae (Brazilian false melissa). J. Ethnopharmacol. 2002; 82: 207-215. |
[53] | Hennebelle T, Sahpaz S, Joseph H and Bailleul F. Phenolics and iridoids of Lippia alba. Natural Product Communications. 2006; 1: 727-730. |
[54] | Hennebelle T, Sahpaz S, Gressier B, Joseph H and Bailleul F. Antioxidant and neurosedative properties of polyphenols and iridoids from Lippia alba. Phytother. Res. 2007; 22: 256-258. |
[55] | Viana GSB, do Vale TG, Rao VSN and Matos FJA. Analgesic and antiinflammatory effects of two chemotypes of Lippia alba: a comparative study. Pharm. Biol. 1998; 36: 347-351. |
[56] | Guerrero MF, Puebla P, Martin ML, Arteag L and San Roman L. Assessment of the antihypertensive and vasodilator effects of ethanolic extracts of some Colombian medicinal plants. J. Ethnopharmacol. 2002; 80: 37-42. |
[57] | Gazola R, Machado D, Ruggiero C, Singi, G, Macedo Alexandre M. Lippia alba, Melissa officinalis and Cymbopogon citratus: effects of the aqueous extracts on the isolated hearts of rats. Pharm. Res. 2004; 50: 477-480. |
[58] | Puertas-Mejia M, Hillebrand S, Stashenko E and Winterhalter P. In vitro radical scavenging activity of essential oils from Columbian plants and fractions from oregano (Origanum vulgare L.) essential oil. Flavour Fragrance J. 2002; 17: 380-384. |
[59] | Stashenko EE, Jaramillo BE and Martinez JR. Comparison of different extraction methods for the analysis of volatile secondary metabolites of Lippia alba (Mill.) N.E. Brown, grown in Colombia, and evaluation of its in vitro antioxidant activity. J. Chromatography A. 2004; 1025: 93-103. |
[60] | Costa MCCD, Aguiar JS and do Nascimiento SC. Atividade citotoxica de extratos brutos de Lippia alba (Mill.) N.E. Brown (Verbenaceae). Acta Farmaceutica Bonaerense. 2004; 23: 349-352. |
[61] | Aiyelagabe. Antibacterial activity of Jatropha multifida roots. Fitoterapia. 2000; 72: 544-546. |
[62] | Nasar-Abbas SM and Halkman AK. Antimicrobial effect of water extract of sumac on the growth of some food born bacteria including pathogens. Int. J. Food Microbiol. 2004; 97: 63-69. |
APA Style
Mamun-Or-Rashid A. N. M., Sen M. K., Jamal M. A. H. M., Nasrin. S. (2013). A Comprehensive Ethnopharmacological Review on Lippia Alba M. International Journal of Biomedical Materials Research, 1(1), 14-20. https://doi.org/10.11648/j.ijbmr.20130101.13
ACS Style
Mamun-Or-Rashid A. N. M.; Sen M. K.; Jamal M. A. H. M.; Nasrin. S. A Comprehensive Ethnopharmacological Review on Lippia Alba M. Int. J. Biomed. Mater. Res. 2013, 1(1), 14-20. doi: 10.11648/j.ijbmr.20130101.13
AMA Style
Mamun-Or-Rashid A. N. M., Sen M. K., Jamal M. A. H. M., Nasrin. S. A Comprehensive Ethnopharmacological Review on Lippia Alba M. Int J Biomed Mater Res. 2013;1(1):14-20. doi: 10.11648/j.ijbmr.20130101.13
@article{10.11648/j.ijbmr.20130101.13, author = {Mamun-Or-Rashid A. N. M. and Sen M. K. and Jamal M. A. H. M. and Nasrin. S}, title = {A Comprehensive Ethnopharmacological Review on Lippia Alba M}, journal = {International Journal of Biomedical Materials Research}, volume = {1}, number = {1}, pages = {14-20}, doi = {10.11648/j.ijbmr.20130101.13}, url = {https://doi.org/10.11648/j.ijbmr.20130101.13}, eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijbmr.20130101.13}, abstract = {The present comprehensive review was conducted in the Department of Biotechnology and Genetic Engineering of Islamic University, Kushtia, to pile up update ethno-pharmacological information of Lippia alba (Mill) that is available in different scientific literatures. L. alba, belongs to the family of verbenaceae, found everywhere in Bangladesh and it is commonly used in folk medicine to treat gastric illnesses, diarrhea, fever, asthma, malaria, and inflammation. Phytochemical analysis showed that the crude extract of fresh leaves consists of some valuable essential oils and that is found to be effective against bacteria, fungus, protozoa, and virus. The present paper also covers the taxonomy, morphology, monograph, usable parts, and distribution of this valuable medicinal plant.}, year = {2013} }
TY - JOUR T1 - A Comprehensive Ethnopharmacological Review on Lippia Alba M AU - Mamun-Or-Rashid A. N. M. AU - Sen M. K. AU - Jamal M. A. H. M. AU - Nasrin. S Y1 - 2013/07/30 PY - 2013 N1 - https://doi.org/10.11648/j.ijbmr.20130101.13 DO - 10.11648/j.ijbmr.20130101.13 T2 - International Journal of Biomedical Materials Research JF - International Journal of Biomedical Materials Research JO - International Journal of Biomedical Materials Research SP - 14 EP - 20 PB - Science Publishing Group SN - 2330-7579 UR - https://doi.org/10.11648/j.ijbmr.20130101.13 AB - The present comprehensive review was conducted in the Department of Biotechnology and Genetic Engineering of Islamic University, Kushtia, to pile up update ethno-pharmacological information of Lippia alba (Mill) that is available in different scientific literatures. L. alba, belongs to the family of verbenaceae, found everywhere in Bangladesh and it is commonly used in folk medicine to treat gastric illnesses, diarrhea, fever, asthma, malaria, and inflammation. Phytochemical analysis showed that the crude extract of fresh leaves consists of some valuable essential oils and that is found to be effective against bacteria, fungus, protozoa, and virus. The present paper also covers the taxonomy, morphology, monograph, usable parts, and distribution of this valuable medicinal plant. VL - 1 IS - 1 ER -