Beta-Lactamase Production Among Uropathogens in Patients Attending Some Hospitals in Kano, Nigeria

Hamza Sule; Abdulhadi Sale Kumurya

doi:doi:10.11648/j.ijbmr.20160403.18

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Beta-Lactamase Production Among Uropathogens in Patients Attending Some Hospitals in Kano, Nigeria

Hamza Sule, Abdulhadi Sale Kumurya

Published in International Journal of Biomedical Materials Research (Volume 4, Issue 3)

Received: 19 August 2016 Accepted: 2 December 2016 Published: 4 January 2017

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Abstract

Ability of bacteria to withstand antibiotic therapy is often associated with resistance. Certain bacteria have the ability to produce some enzymes, like Beta–Lactamase, which confers resistance to some groups of antibiotics like penicillins and cephalosporins. The study focused on producers of these enzymes among uropathogens. A total of one hundred and forteen isolates (114) were screened, out of which seventy one 71 (62.3%) were found positive for the enzymes. Eschericia coli had the highest positivity rate 40 (56.3%). Followed by Klebsiella spp., Staphylococcus aureus, Staphylociccus saprophyticcus, Proteus mirabilis, and Pseudomonas aeruginosa with 15 (21.1%), 7 (10.0%), 5 (7.0%), 3 (4.2%), and 1 (1.4%) respectively. In the same vein, it was discovered that, isolates of females’ origin, produced more of the enzymes than those of their males counterpart. This was indicated by the production of the enzyme by at least one isolate in each of the species isolated from female samples while in males, some species did not even produce any of the enzymes. Age-wise distribution of the enzymes showed that, 21- 30, and 31-40 age groups had all the isolates producing the enzymes in varying frequencies. Only Pseudomonas aeruginosa that produced its enzyme outside these age groups. Isolates of females origin had more of the enzymes produced in all the species compared to those from males, with ratios of; 26:14, 11:4, 5:2, 3:2, 2:1, and 1:0 for, E coli, Klebsiella species, Staphylococcus aureus, Staphylococcus saprophyticus, Proteus mirabilis, and Pseudomonas aeruginosa respectively.

Published in	International Journal of Biomedical Materials Research (Volume 4, Issue 3)
DOI	10.11648/j.ijbmr.20160403.18
Page(s)	58-62
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2017. Published by Science Publishing Group

Keywords

Urinary Tract Infections, Uropathogens, Beta-Lactamase, Kano

References

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[2]	Alabi, O. S., Onyenwe, N. E. Satoye, K. A. and Adeleke, O. E. (2014). Prevalence of extended-spectrum β-lactamase producing isolates from asymptomatic bacteriuria among students in a tertiary institution in Ibadan, Nigeria. Nature and Science 12 (4): 113.
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APA Style

Hamza Sule, Abdulhadi Sale Kumurya. (2017). Beta-Lactamase Production Among Uropathogens in Patients Attending Some Hospitals in Kano, Nigeria. International Journal of Biomedical Materials Research, 4(3), 58-62. https://doi.org/10.11648/j.ijbmr.20160403.18

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ACS Style

Hamza Sule; Abdulhadi Sale Kumurya. Beta-Lactamase Production Among Uropathogens in Patients Attending Some Hospitals in Kano, Nigeria. Int. J. Biomed. Mater. Res. 2017, 4(3), 58-62. doi: 10.11648/j.ijbmr.20160403.18

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AMA Style

Hamza Sule, Abdulhadi Sale Kumurya. Beta-Lactamase Production Among Uropathogens in Patients Attending Some Hospitals in Kano, Nigeria. Int J Biomed Mater Res. 2017;4(3):58-62. doi: 10.11648/j.ijbmr.20160403.18

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@article{10.11648/j.ijbmr.20160403.18,
  author = {Hamza Sule and Abdulhadi Sale Kumurya},
  title = {Beta-Lactamase Production Among Uropathogens in Patients Attending Some Hospitals in Kano, Nigeria},
  journal = {International Journal of Biomedical Materials Research},
  volume = {4},
  number = {3},
  pages = {58-62},
  doi = {10.11648/j.ijbmr.20160403.18},
  url = {https://doi.org/10.11648/j.ijbmr.20160403.18},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijbmr.20160403.18},
  abstract = {Ability of bacteria to withstand antibiotic therapy is often associated with resistance. Certain bacteria have the ability to produce some enzymes, like Beta–Lactamase, which confers resistance to some groups of antibiotics like penicillins and cephalosporins. The study focused on producers of these enzymes among uropathogens. A total of one hundred and forteen isolates (114) were screened, out of which seventy one 71 (62.3%) were found positive for the enzymes. Eschericia coli had the highest positivity rate 40 (56.3%). Followed by Klebsiella spp., Staphylococcus aureus, Staphylociccus saprophyticcus, Proteus mirabilis, and Pseudomonas aeruginosa with 15 (21.1%), 7 (10.0%), 5 (7.0%), 3 (4.2%), and 1 (1.4%) respectively. In the same vein, it was discovered that, isolates of females’ origin, produced more of the enzymes than those of their males counterpart. This was indicated by the production of the enzyme by at least one isolate in each of the species isolated from female samples while in males, some species did not even produce any of the enzymes. Age-wise distribution of the enzymes showed that, 21- 30, and 31-40 age groups had all the isolates producing the enzymes in varying frequencies. Only Pseudomonas aeruginosa that produced its enzyme outside these age groups. Isolates of females origin had more of the enzymes produced in all the species compared to those from males, with ratios of; 26:14, 11:4, 5:2, 3:2, 2:1, and 1:0 for, E coli, Klebsiella species, Staphylococcus aureus, Staphylococcus saprophyticus, Proteus mirabilis, and Pseudomonas aeruginosa respectively.},
 year = {2017}
}

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TY  - JOUR
T1  - Beta-Lactamase Production Among Uropathogens in Patients Attending Some Hospitals in Kano, Nigeria
AU  - Hamza Sule
AU  - Abdulhadi Sale Kumurya
Y1  - 2017/01/04
PY  - 2017
N1  - https://doi.org/10.11648/j.ijbmr.20160403.18
DO  - 10.11648/j.ijbmr.20160403.18
T2  - International Journal of Biomedical Materials Research
JF  - International Journal of Biomedical Materials Research
JO  - International Journal of Biomedical Materials Research
SP  - 58
EP  - 62
PB  - Science Publishing Group
SN  - 2330-7579
UR  - https://doi.org/10.11648/j.ijbmr.20160403.18
AB  - Ability of bacteria to withstand antibiotic therapy is often associated with resistance. Certain bacteria have the ability to produce some enzymes, like Beta–Lactamase, which confers resistance to some groups of antibiotics like penicillins and cephalosporins. The study focused on producers of these enzymes among uropathogens. A total of one hundred and forteen isolates (114) were screened, out of which seventy one 71 (62.3%) were found positive for the enzymes. Eschericia coli had the highest positivity rate 40 (56.3%). Followed by Klebsiella spp., Staphylococcus aureus, Staphylociccus saprophyticcus, Proteus mirabilis, and Pseudomonas aeruginosa with 15 (21.1%), 7 (10.0%), 5 (7.0%), 3 (4.2%), and 1 (1.4%) respectively. In the same vein, it was discovered that, isolates of females’ origin, produced more of the enzymes than those of their males counterpart. This was indicated by the production of the enzyme by at least one isolate in each of the species isolated from female samples while in males, some species did not even produce any of the enzymes. Age-wise distribution of the enzymes showed that, 21- 30, and 31-40 age groups had all the isolates producing the enzymes in varying frequencies. Only Pseudomonas aeruginosa that produced its enzyme outside these age groups. Isolates of females origin had more of the enzymes produced in all the species compared to those from males, with ratios of; 26:14, 11:4, 5:2, 3:2, 2:1, and 1:0 for, E coli, Klebsiella species, Staphylococcus aureus, Staphylococcus saprophyticus, Proteus mirabilis, and Pseudomonas aeruginosa respectively.
VL  - 4
IS  - 3
ER  -

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Author Information

Hamza Sule

Department of Medical Laboratory Science, Faculty of Allied Health Sciences, Bayero University, Kano, Nigeria
Abdulhadi Sale Kumurya

Department of Medical Laboratory Science, Faculty of Allied Health Sciences, Bayero University, Kano, Nigeria

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Hamza Sule, Abdulhadi Sale Kumurya. (2017). Beta-Lactamase Production Among Uropathogens in Patients Attending Some Hospitals in Kano, Nigeria. International Journal of Biomedical Materials Research, 4(3), 58-62. https://doi.org/10.11648/j.ijbmr.20160403.18

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ACS Style

Hamza Sule; Abdulhadi Sale Kumurya. Beta-Lactamase Production Among Uropathogens in Patients Attending Some Hospitals in Kano, Nigeria. Int. J. Biomed. Mater. Res. 2017, 4(3), 58-62. doi: 10.11648/j.ijbmr.20160403.18

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AMA Style

Hamza Sule, Abdulhadi Sale Kumurya. Beta-Lactamase Production Among Uropathogens in Patients Attending Some Hospitals in Kano, Nigeria. Int J Biomed Mater Res. 2017;4(3):58-62. doi: 10.11648/j.ijbmr.20160403.18

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@article{10.11648/j.ijbmr.20160403.18,
  author = {Hamza Sule and Abdulhadi Sale Kumurya},
  title = {Beta-Lactamase Production Among Uropathogens in Patients Attending Some Hospitals in Kano, Nigeria},
  journal = {International Journal of Biomedical Materials Research},
  volume = {4},
  number = {3},
  pages = {58-62},
  doi = {10.11648/j.ijbmr.20160403.18},
  url = {https://doi.org/10.11648/j.ijbmr.20160403.18},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijbmr.20160403.18},
  abstract = {Ability of bacteria to withstand antibiotic therapy is often associated with resistance. Certain bacteria have the ability to produce some enzymes, like Beta–Lactamase, which confers resistance to some groups of antibiotics like penicillins and cephalosporins. The study focused on producers of these enzymes among uropathogens. A total of one hundred and forteen isolates (114) were screened, out of which seventy one 71 (62.3%) were found positive for the enzymes. Eschericia coli had the highest positivity rate 40 (56.3%). Followed by Klebsiella spp., Staphylococcus aureus, Staphylociccus saprophyticcus, Proteus mirabilis, and Pseudomonas aeruginosa with 15 (21.1%), 7 (10.0%), 5 (7.0%), 3 (4.2%), and 1 (1.4%) respectively. In the same vein, it was discovered that, isolates of females’ origin, produced more of the enzymes than those of their males counterpart. This was indicated by the production of the enzyme by at least one isolate in each of the species isolated from female samples while in males, some species did not even produce any of the enzymes. Age-wise distribution of the enzymes showed that, 21- 30, and 31-40 age groups had all the isolates producing the enzymes in varying frequencies. Only Pseudomonas aeruginosa that produced its enzyme outside these age groups. Isolates of females origin had more of the enzymes produced in all the species compared to those from males, with ratios of; 26:14, 11:4, 5:2, 3:2, 2:1, and 1:0 for, E coli, Klebsiella species, Staphylococcus aureus, Staphylococcus saprophyticus, Proteus mirabilis, and Pseudomonas aeruginosa respectively.},
 year = {2017}
}

Copy | Download

TY  - JOUR
T1  - Beta-Lactamase Production Among Uropathogens in Patients Attending Some Hospitals in Kano, Nigeria
AU  - Hamza Sule
AU  - Abdulhadi Sale Kumurya
Y1  - 2017/01/04
PY  - 2017
N1  - https://doi.org/10.11648/j.ijbmr.20160403.18
DO  - 10.11648/j.ijbmr.20160403.18
T2  - International Journal of Biomedical Materials Research
JF  - International Journal of Biomedical Materials Research
JO  - International Journal of Biomedical Materials Research
SP  - 58
EP  - 62
PB  - Science Publishing Group
SN  - 2330-7579
UR  - https://doi.org/10.11648/j.ijbmr.20160403.18
AB  - Ability of bacteria to withstand antibiotic therapy is often associated with resistance. Certain bacteria have the ability to produce some enzymes, like Beta–Lactamase, which confers resistance to some groups of antibiotics like penicillins and cephalosporins. The study focused on producers of these enzymes among uropathogens. A total of one hundred and forteen isolates (114) were screened, out of which seventy one 71 (62.3%) were found positive for the enzymes. Eschericia coli had the highest positivity rate 40 (56.3%). Followed by Klebsiella spp., Staphylococcus aureus, Staphylociccus saprophyticcus, Proteus mirabilis, and Pseudomonas aeruginosa with 15 (21.1%), 7 (10.0%), 5 (7.0%), 3 (4.2%), and 1 (1.4%) respectively. In the same vein, it was discovered that, isolates of females’ origin, produced more of the enzymes than those of their males counterpart. This was indicated by the production of the enzyme by at least one isolate in each of the species isolated from female samples while in males, some species did not even produce any of the enzymes. Age-wise distribution of the enzymes showed that, 21- 30, and 31-40 age groups had all the isolates producing the enzymes in varying frequencies. Only Pseudomonas aeruginosa that produced its enzyme outside these age groups. Isolates of females origin had more of the enzymes produced in all the species compared to those from males, with ratios of; 26:14, 11:4, 5:2, 3:2, 2:1, and 1:0 for, E coli, Klebsiella species, Staphylococcus aureus, Staphylococcus saprophyticus, Proteus mirabilis, and Pseudomonas aeruginosa respectively.
VL  - 4
IS  - 3
ER  -

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