Clinical and Paraclinical Profile of Male Infertility in Two Hospitals in Low - Income Setting, Cameroon

Frantz Guy Epoupa Ngalle; Landry Oriole Mbouche; Axel Stephane Nwaha Makon; Edouard Herve Moby Mpah; Kelly Donfack; Guy Sadeu Wafeu; Charlotte Tchente Nguefack

doi:doi:10.11648/j.ijcu.20210502.22

Clinical and Paraclinical Profile of Male Infertility in Two Hospitals in Low - Income Setting, Cameroon

Frantz Guy Epoupa Ngalle, Landry Oriole Mbouche, Axel Stephane Nwaha Makon, Edouard Herve Moby Mpah, Kelly Donfack, Guy Sadeu Wafeu, Charlotte Tchente Nguefack

Published in International Journal of Clinical Urology (Volume 5, Issue 2)

Received: 28 November 2021 Accepted: 17 December 2021 Published: 29 December 2021

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Abstract

Background: Male infertility has diverse aetiologies and contribute to more than 50% of infertility, but workup required for the diagnosis are not always available in low-income settings. Methods: We aimed to describe clinical and paraclinical profile of male infertility in low- and middle-income setting. This was a retrospective cross-sectional study in two urology referral hospitals, including consenting male partners of infertile couples. Sociodemographic, clinical and paraclinical (including semen analysis, ultrasound results and hormonal level) data were collected from patient’s records and interview. Qualitative and quantitative variables were described with corresponding statistics. Results: Overall 137 participants were included in this study with a mean age of 35.4±7.3 years. Erectile dysfunction (35%), and testicular pain (27.7%) were the most common symptoms. The most frequent abnormalities were asthenospermia, oligospermia, azoospermia and necrospermia found in 69.3%, 59.9%, 21.2% and 19.7% of subjects respectively. Normal value of testosterone, luteinizing hormone, Follicle Stimulating Hormone and prolactin values were found in more than half of participants on ultrasound analysis, varicocele was present in 58.9% of subjects and testicular hypotrophy in 45.8%. Conclusion: Seminal and ultrasound abnormalities are common in male with infertility in our context. Sexual Transmitting Infection and varicocele seems to be predominant aetiologies. Further research should be carried out to investigate on the different aetiologies of fertility in men for better management.

Published in	International Journal of Clinical Urology (Volume 5, Issue 2)
DOI	10.11648/j.ijcu.20210502.22
Page(s)	118-122
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Male Infertility, Paraclinical Profile, Cameroon

References

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[3]	Mascarenhas MN, Flaxman SR, Boerma T, et al (2012) National, Regional, and Global Trends in Infertility Prevalence Since 1990: A Systematic Analysis of 277 Health Surveys. PLoS Med 9: e1001356. https://doi.org/10.1371/journal.pmed.1001356.
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[6]	Leslie SW, Siref LE, Soon-Sutton TL, Khan MA (2021) Male Infertility. In: StatPearls. StatPearls Publishing, Treasure Island (FL).
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[8]	Cooper TG, Noonan E, von Eckardstein S, et al (2010) World Health Organization reference values for human semen characteristics. Human Reproduction Update 16: 231–245. https://doi.org/10.1093/humupd/dmp048.
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[13]	Leslie SW, Sajjad H, Siref LE (2021) Varicocele. StatPearls Publishing.
[14]	Kirakoya B, Barnabé Z, Abdoul Karim P, et al (2015) Epidemiological and Clinical Profile of Male Hypofertility in Consultation at the Urology-Andrology of Yalgado Ouedraogo Teaching Hospital (Burkina Faso). ASM 05: 1–6. https://doi.org/10.4236/asm.2015.51001.
[15]	Pajovic B, Radojevic N, Vukovic M, Stjepcevic A (2013) Semen analysis before and after antibiotic treatment of asymptomatic chlamydia- and ureaplasma-related pyospermia. Andrologia 45: 266–271. https://doi.org/10.1111/and.12004.
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Frantz Guy Epoupa Ngalle, Landry Oriole Mbouche, Axel Stephane Nwaha Makon, Edouard Herve Moby Mpah, Kelly Donfack, et al. (2021). Clinical and Paraclinical Profile of Male Infertility in Two Hospitals in Low - Income Setting, Cameroon. International Journal of Clinical Urology, 5(2), 118-122. https://doi.org/10.11648/j.ijcu.20210502.22

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Frantz Guy Epoupa Ngalle; Landry Oriole Mbouche; Axel Stephane Nwaha Makon; Edouard Herve Moby Mpah; Kelly Donfack, et al. Clinical and Paraclinical Profile of Male Infertility in Two Hospitals in Low - Income Setting, Cameroon. Int. J. Clin. Urol. 2021, 5(2), 118-122. doi: 10.11648/j.ijcu.20210502.22

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AMA Style

Frantz Guy Epoupa Ngalle, Landry Oriole Mbouche, Axel Stephane Nwaha Makon, Edouard Herve Moby Mpah, Kelly Donfack, et al. Clinical and Paraclinical Profile of Male Infertility in Two Hospitals in Low - Income Setting, Cameroon. Int J Clin Urol. 2021;5(2):118-122. doi: 10.11648/j.ijcu.20210502.22

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@article{10.11648/j.ijcu.20210502.22,
  author = {Frantz Guy Epoupa Ngalle and Landry Oriole Mbouche and Axel Stephane Nwaha Makon and Edouard Herve Moby Mpah and Kelly Donfack and Guy Sadeu Wafeu and Charlotte Tchente Nguefack},
  title = {Clinical and Paraclinical Profile of Male Infertility in Two Hospitals in Low - Income Setting, Cameroon},
  journal = {International Journal of Clinical Urology},
  volume = {5},
  number = {2},
  pages = {118-122},
  doi = {10.11648/j.ijcu.20210502.22},
  url = {https://doi.org/10.11648/j.ijcu.20210502.22},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcu.20210502.22},
  abstract = {Background: Male infertility has diverse aetiologies and contribute to more than 50% of infertility, but workup required for the diagnosis are not always available in low-income settings. Methods: We aimed to describe clinical and paraclinical profile of male infertility in low- and middle-income setting. This was a retrospective cross-sectional study in two urology referral hospitals, including consenting male partners of infertile couples. Sociodemographic, clinical and paraclinical (including semen analysis, ultrasound results and hormonal level) data were collected from patient’s records and interview. Qualitative and quantitative variables were described with corresponding statistics. Results: Overall 137 participants were included in this study with a mean age of 35.4±7.3 years. Erectile dysfunction (35%), and testicular pain (27.7%) were the most common symptoms. The most frequent abnormalities were asthenospermia, oligospermia, azoospermia and necrospermia found in 69.3%, 59.9%, 21.2% and 19.7% of subjects respectively. Normal value of testosterone, luteinizing hormone, Follicle Stimulating Hormone and prolactin values were found in more than half of participants on ultrasound analysis, varicocele was present in 58.9% of subjects and testicular hypotrophy in 45.8%. Conclusion: Seminal and ultrasound abnormalities are common in male with infertility in our context. Sexual Transmitting Infection and varicocele seems to be predominant aetiologies. Further research should be carried out to investigate on the different aetiologies of fertility in men for better management.},
 year = {2021}
}

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TY - JOUR
T1 - Clinical and Paraclinical Profile of Male Infertility in Two Hospitals in Low - Income Setting, Cameroon
AU - Frantz Guy Epoupa Ngalle
AU - Landry Oriole Mbouche
AU - Axel Stephane Nwaha Makon
AU - Edouard Herve Moby Mpah
AU - Kelly Donfack
AU - Guy Sadeu Wafeu
AU - Charlotte Tchente Nguefack
Y1 - 2021/12/29
PY - 2021
N1 - https://doi.org/10.11648/j.ijcu.20210502.22
DO - 10.11648/j.ijcu.20210502.22
T2 - International Journal of Clinical Urology
JF - International Journal of Clinical Urology
JO - International Journal of Clinical Urology
SP - 118
EP - 122
PB - Science Publishing Group
SN - 2640-1355
UR - https://doi.org/10.11648/j.ijcu.20210502.22
AB - Background: Male infertility has diverse aetiologies and contribute to more than 50% of infertility, but workup required for the diagnosis are not always available in low-income settings. Methods: We aimed to describe clinical and paraclinical profile of male infertility in low- and middle-income setting. This was a retrospective cross-sectional study in two urology referral hospitals, including consenting male partners of infertile couples. Sociodemographic, clinical and paraclinical (including semen analysis, ultrasound results and hormonal level) data were collected from patient’s records and interview. Qualitative and quantitative variables were described with corresponding statistics. Results: Overall 137 participants were included in this study with a mean age of 35.4±7.3 years. Erectile dysfunction (35%), and testicular pain (27.7%) were the most common symptoms. The most frequent abnormalities were asthenospermia, oligospermia, azoospermia and necrospermia found in 69.3%, 59.9%, 21.2% and 19.7% of subjects respectively. Normal value of testosterone, luteinizing hormone, Follicle Stimulating Hormone and prolactin values were found in more than half of participants on ultrasound analysis, varicocele was present in 58.9% of subjects and testicular hypotrophy in 45.8%. Conclusion: Seminal and ultrasound abnormalities are common in male with infertility in our context. Sexual Transmitting Infection and varicocele seems to be predominant aetiologies. Further research should be carried out to investigate on the different aetiologies of fertility in men for better management.
VL - 5
IS - 2
ER -

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Author Information

Frantz Guy Epoupa Ngalle

Department of Surgery, Douala General Hospital, Douala, Cameroon
Landry Oriole Mbouche

Department of Surgery and Sub-specialities, Faculty of Medicine and Biomedical Sciences, University of Yaounde I, Yaounde, Cameroon
Axel Stephane Nwaha Makon

Department of Surgery and Sub-specialities, Faculty of Medicine and Biomedical Sciences, University of Yaounde I, Yaounde, Cameroon
Edouard Herve Moby Mpah

Department of Surgery, Douala General Hospital, Douala, Cameroon
Kelly Donfack

Department of Surgery, Faculty of Medicine and Pharmaceutical Sciences, University of Douala, Douala, Cameroon
Guy Sadeu Wafeu

Centre for Research on Filariasis and Other Tropical Diseases, Yaounde, Cameroon
Charlotte Tchente Nguefack

Department of Surgery, Faculty of Medicine and Pharmaceutical Sciences, University of Douala, Douala, Cameroon

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APA Style

Frantz Guy Epoupa Ngalle, Landry Oriole Mbouche, Axel Stephane Nwaha Makon, Edouard Herve Moby Mpah, Kelly Donfack, et al. (2021). Clinical and Paraclinical Profile of Male Infertility in Two Hospitals in Low - Income Setting, Cameroon. International Journal of Clinical Urology, 5(2), 118-122. https://doi.org/10.11648/j.ijcu.20210502.22

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Frantz Guy Epoupa Ngalle; Landry Oriole Mbouche; Axel Stephane Nwaha Makon; Edouard Herve Moby Mpah; Kelly Donfack, et al. Clinical and Paraclinical Profile of Male Infertility in Two Hospitals in Low - Income Setting, Cameroon. Int. J. Clin. Urol. 2021, 5(2), 118-122. doi: 10.11648/j.ijcu.20210502.22

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AMA Style

Frantz Guy Epoupa Ngalle, Landry Oriole Mbouche, Axel Stephane Nwaha Makon, Edouard Herve Moby Mpah, Kelly Donfack, et al. Clinical and Paraclinical Profile of Male Infertility in Two Hospitals in Low - Income Setting, Cameroon. Int J Clin Urol. 2021;5(2):118-122. doi: 10.11648/j.ijcu.20210502.22

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@article{10.11648/j.ijcu.20210502.22,
  author = {Frantz Guy Epoupa Ngalle and Landry Oriole Mbouche and Axel Stephane Nwaha Makon and Edouard Herve Moby Mpah and Kelly Donfack and Guy Sadeu Wafeu and Charlotte Tchente Nguefack},
  title = {Clinical and Paraclinical Profile of Male Infertility in Two Hospitals in Low - Income Setting, Cameroon},
  journal = {International Journal of Clinical Urology},
  volume = {5},
  number = {2},
  pages = {118-122},
  doi = {10.11648/j.ijcu.20210502.22},
  url = {https://doi.org/10.11648/j.ijcu.20210502.22},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcu.20210502.22},
  abstract = {Background: Male infertility has diverse aetiologies and contribute to more than 50% of infertility, but workup required for the diagnosis are not always available in low-income settings. Methods: We aimed to describe clinical and paraclinical profile of male infertility in low- and middle-income setting. This was a retrospective cross-sectional study in two urology referral hospitals, including consenting male partners of infertile couples. Sociodemographic, clinical and paraclinical (including semen analysis, ultrasound results and hormonal level) data were collected from patient’s records and interview. Qualitative and quantitative variables were described with corresponding statistics. Results: Overall 137 participants were included in this study with a mean age of 35.4±7.3 years. Erectile dysfunction (35%), and testicular pain (27.7%) were the most common symptoms. The most frequent abnormalities were asthenospermia, oligospermia, azoospermia and necrospermia found in 69.3%, 59.9%, 21.2% and 19.7% of subjects respectively. Normal value of testosterone, luteinizing hormone, Follicle Stimulating Hormone and prolactin values were found in more than half of participants on ultrasound analysis, varicocele was present in 58.9% of subjects and testicular hypotrophy in 45.8%. Conclusion: Seminal and ultrasound abnormalities are common in male with infertility in our context. Sexual Transmitting Infection and varicocele seems to be predominant aetiologies. Further research should be carried out to investigate on the different aetiologies of fertility in men for better management.},
 year = {2021}
}

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