Prognosis of Hydronephrosis in Cervical Cancer at the Libreville Cancer Institute

Steevy Ndang Ngou Milama; Adrien Mougougou; Euloge Ibinga; Dimitri Mbethe; Audrey Bikene Bi Ntoutoume; Ernest Belembaogo

doi:doi:10.11648/j.ijcu.20220601.21

Prognosis of Hydronephrosis in Cervical Cancer at the Libreville Cancer Institute

Steevy Ndang Ngou Milama, Adrien Mougougou, Euloge Ibinga, Dimitri Mbethe, Audrey Bikene Bi Ntoutoume, Ernest Belembaogo

Published in International Journal of Clinical Urology (Volume 6, Issue 1)

Received: 28 January 2022 Accepted: 21 February 2022 Published: 9 March 2022

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Abstract

Introduction: In Gabon, cervical cancer is second only to breast cancer. Urological complications such as ureteral obstruction and hydronephrosis can occur in the course of this pathology. This work aimed to evaluate the impact of hydronephrosis on the overall survival of patients. Patients and Methods: the records of patients followed at the ICL from January 1, 2015, to December 31, 2019, a period of 5 years, were collected. The study included patients followed for cervical cancer and who had a complete medical record: histological evidence and extension workup. Patients not followed up at ICL were not included in the study. Results: the records of 183 patients with cervical cancer during the study period were retained. The mean age was 55.3±14.1 years, with extremes of 21 and 89 years. Stages II, III, and IV accounted for 87.4% of cancers, and stages III and IV (51.3%) represented the majority of clinical stages. In univariate survival analyses, assessed from the date of cancer diagnosis, patients with hydronephrosis during their cancer had poor survival compared with those without. Patients who had no hydronephrosis had better overall survival at three years (85%) compared with those who had developed urologic complications (54%). Conclusion: hydronephrosis has a negative effect on the prognosis of cervical cancer, and indeed, it significantly decreases the overall survival of patients with cervical cancer. Therefore, it is essential to screen them systematically to treat them as effectively as possible.

Published in	International Journal of Clinical Urology (Volume 6, Issue 1)
DOI	10.11648/j.ijcu.20220601.21
Page(s)	45-50
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2022. Published by Science Publishing Group

Keywords

Prognosis, Cervical Cancer, Hydronephrosis, Survival

References

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[3]	Atuhairwe S, Busingye RB, Sekikubo M. Urologic complications among women with advanced cervical at a tertiary referral hospital in Uganda. Int J Gynecol Obstet. 2011; 115 (3): 282-4.
[4]	Chao KS, Leung WM, Grigsby PW, et al. The clinical implications of hydronephrosis and the level of ureteral obstruction in stage IIIB cervical cancer. Int Radiat J Oncol Biol Phys 1998; 40: 1095-100.
[5]	Bosch A, Frias Z, Valda G. Prognostic significance of ureteral obstruction in carcinoma of the cervix uteri. Acta Radiol Ther Biol 1973; 12: 47-56.
[6]	Bannour N, Boughizane S, Naifer R. Le cancer invasif du col utérin dans le centre tunisien. Approches épidémiologiques, cliniques et thérapeutiques. Étude rétrospective de 96 cas. [Invasive cervical cancer in central Tunisia: Epidemiological, clinical and therapeutic approaches. Retrospective study of 96 cases] Oncologie, 6 (7): 481–488.
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[8]	Lankoandé J; Sakande B. Le cancer du col utérin dans le service de gynécologie–obstétrique au centre hospitalier national Yalgado Ouedraogo de Ouagadougou : aspects épidémio-cliniques et anatomo-pathologiques. [Cervical cancer in the gynecology-obstetrics department of the National Hospital Center Yalgado Ouedraogo de Ouagadoudou (Burkina-Faso]. Méd Afrique Noire; 1998: 45 (7).
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[11]	Gloku MR, Kerem DS, Cihan T. Effect of hydronephrosis on survival in advanced stage cervical cancer Asian Pac J Cancer Prev 2015; 16 (10): 4219-4222.
[12]	Patel K, Foster NR, Kumar A, et al. Hydronephrosis in patients with cervical cancer: an assessment of mortality and survival. Support Care Cancer 2015; 23: 1303-9.
[13]	Pradhan TS, Duan H, Katsoulakis E, et al. Hydronephrosis as a prognostic indicator of survival in advanced cervix cancer. Int J Gynecol Cancer 2011; 21: 1091-6.
[14]	Vasilios Pergialiotis, Ioannis Bellos, Nikolaos Thomakos et al. Survival outcomes of patients with cervical cancer and accompanying hydronephrosis: A systematic review of the literature. Oncol Rev 2019 Jan 15; 13 (1): 387. doi: 10.4081/oncol.2019.387.
[15]	Patrick J Maguire, Aleksandra Sobota, Doug Mulholland, J Mark Ryan, Noreen Gleeson. Incidence, management, and sequelae of ureteric obstruction in women with cervical cancer. Support Care Cancer 2020; 28 (2): 725-730. doi: 10.1007/s00520-019-04851-9.
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Steevy Ndang Ngou Milama, Adrien Mougougou, Euloge Ibinga, Dimitri Mbethe, Audrey Bikene Bi Ntoutoume, et al. (2022). Prognosis of Hydronephrosis in Cervical Cancer at the Libreville Cancer Institute. International Journal of Clinical Urology, 6(1), 45-50. https://doi.org/10.11648/j.ijcu.20220601.21

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Steevy Ndang Ngou Milama; Adrien Mougougou; Euloge Ibinga; Dimitri Mbethe; Audrey Bikene Bi Ntoutoume, et al. Prognosis of Hydronephrosis in Cervical Cancer at the Libreville Cancer Institute. Int. J. Clin. Urol. 2022, 6(1), 45-50. doi: 10.11648/j.ijcu.20220601.21

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AMA Style

Steevy Ndang Ngou Milama, Adrien Mougougou, Euloge Ibinga, Dimitri Mbethe, Audrey Bikene Bi Ntoutoume, et al. Prognosis of Hydronephrosis in Cervical Cancer at the Libreville Cancer Institute. Int J Clin Urol. 2022;6(1):45-50. doi: 10.11648/j.ijcu.20220601.21

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@article{10.11648/j.ijcu.20220601.21,
  author = {Steevy Ndang Ngou Milama and Adrien Mougougou and Euloge Ibinga and Dimitri Mbethe and Audrey Bikene Bi Ntoutoume and Ernest Belembaogo},
  title = {Prognosis of Hydronephrosis in Cervical Cancer at the Libreville Cancer Institute},
  journal = {International Journal of Clinical Urology},
  volume = {6},
  number = {1},
  pages = {45-50},
  doi = {10.11648/j.ijcu.20220601.21},
  url = {https://doi.org/10.11648/j.ijcu.20220601.21},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcu.20220601.21},
  abstract = {Introduction: In Gabon, cervical cancer is second only to breast cancer. Urological complications such as ureteral obstruction and hydronephrosis can occur in the course of this pathology. This work aimed to evaluate the impact of hydronephrosis on the overall survival of patients. Patients and Methods: the records of patients followed at the ICL from January 1, 2015, to December 31, 2019, a period of 5 years, were collected. The study included patients followed for cervical cancer and who had a complete medical record: histological evidence and extension workup. Patients not followed up at ICL were not included in the study. Results: the records of 183 patients with cervical cancer during the study period were retained. The mean age was 55.3±14.1 years, with extremes of 21 and 89 years. Stages II, III, and IV accounted for 87.4% of cancers, and stages III and IV (51.3%) represented the majority of clinical stages. In univariate survival analyses, assessed from the date of cancer diagnosis, patients with hydronephrosis during their cancer had poor survival compared with those without. Patients who had no hydronephrosis had better overall survival at three years (85%) compared with those who had developed urologic complications (54%). Conclusion: hydronephrosis has a negative effect on the prognosis of cervical cancer, and indeed, it significantly decreases the overall survival of patients with cervical cancer. Therefore, it is essential to screen them systematically to treat them as effectively as possible.},
 year = {2022}
}

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TY - JOUR
T1 - Prognosis of Hydronephrosis in Cervical Cancer at the Libreville Cancer Institute
AU - Steevy Ndang Ngou Milama
AU - Adrien Mougougou
AU - Euloge Ibinga
AU - Dimitri Mbethe
AU - Audrey Bikene Bi Ntoutoume
AU - Ernest Belembaogo
Y1 - 2022/03/09
PY - 2022
N1 - https://doi.org/10.11648/j.ijcu.20220601.21
DO - 10.11648/j.ijcu.20220601.21
T2 - International Journal of Clinical Urology
JF - International Journal of Clinical Urology
JO - International Journal of Clinical Urology
SP - 45
EP - 50
PB - Science Publishing Group
SN - 2640-1355
UR - https://doi.org/10.11648/j.ijcu.20220601.21
AB - Introduction: In Gabon, cervical cancer is second only to breast cancer. Urological complications such as ureteral obstruction and hydronephrosis can occur in the course of this pathology. This work aimed to evaluate the impact of hydronephrosis on the overall survival of patients. Patients and Methods: the records of patients followed at the ICL from January 1, 2015, to December 31, 2019, a period of 5 years, were collected. The study included patients followed for cervical cancer and who had a complete medical record: histological evidence and extension workup. Patients not followed up at ICL were not included in the study. Results: the records of 183 patients with cervical cancer during the study period were retained. The mean age was 55.3±14.1 years, with extremes of 21 and 89 years. Stages II, III, and IV accounted for 87.4% of cancers, and stages III and IV (51.3%) represented the majority of clinical stages. In univariate survival analyses, assessed from the date of cancer diagnosis, patients with hydronephrosis during their cancer had poor survival compared with those without. Patients who had no hydronephrosis had better overall survival at three years (85%) compared with those who had developed urologic complications (54%). Conclusion: hydronephrosis has a negative effect on the prognosis of cervical cancer, and indeed, it significantly decreases the overall survival of patients with cervical cancer. Therefore, it is essential to screen them systematically to treat them as effectively as possible.
VL - 6
IS - 1
ER -

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Author Information

Steevy Ndang Ngou Milama

Urology Department, University Hospital Center of Libreville, Libreville, Gabon
Adrien Mougougou

Urology Department, University Hospital Center of Libreville, Libreville, Gabon
Euloge Ibinga

Department of Epidemiology and Statistics, Université des Sciences de la Santé (USS), Libreville, Gabon
Dimitri Mbethe

Urology Department, University Hospital Center of Libreville, Libreville, Gabon
Audrey Bikene Bi Ntoutoume

Institut de Cancérologie de Libreville (ICL), Libreville, Gabon
Ernest Belembaogo

Institut de Cancérologie de Libreville (ICL), Libreville, Gabon

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APA Style

Steevy Ndang Ngou Milama, Adrien Mougougou, Euloge Ibinga, Dimitri Mbethe, Audrey Bikene Bi Ntoutoume, et al. (2022). Prognosis of Hydronephrosis in Cervical Cancer at the Libreville Cancer Institute. International Journal of Clinical Urology, 6(1), 45-50. https://doi.org/10.11648/j.ijcu.20220601.21

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ACS Style

Steevy Ndang Ngou Milama; Adrien Mougougou; Euloge Ibinga; Dimitri Mbethe; Audrey Bikene Bi Ntoutoume, et al. Prognosis of Hydronephrosis in Cervical Cancer at the Libreville Cancer Institute. Int. J. Clin. Urol. 2022, 6(1), 45-50. doi: 10.11648/j.ijcu.20220601.21

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AMA Style

Steevy Ndang Ngou Milama, Adrien Mougougou, Euloge Ibinga, Dimitri Mbethe, Audrey Bikene Bi Ntoutoume, et al. Prognosis of Hydronephrosis in Cervical Cancer at the Libreville Cancer Institute. Int J Clin Urol. 2022;6(1):45-50. doi: 10.11648/j.ijcu.20220601.21

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@article{10.11648/j.ijcu.20220601.21,
  author = {Steevy Ndang Ngou Milama and Adrien Mougougou and Euloge Ibinga and Dimitri Mbethe and Audrey Bikene Bi Ntoutoume and Ernest Belembaogo},
  title = {Prognosis of Hydronephrosis in Cervical Cancer at the Libreville Cancer Institute},
  journal = {International Journal of Clinical Urology},
  volume = {6},
  number = {1},
  pages = {45-50},
  doi = {10.11648/j.ijcu.20220601.21},
  url = {https://doi.org/10.11648/j.ijcu.20220601.21},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcu.20220601.21},
  abstract = {Introduction: In Gabon, cervical cancer is second only to breast cancer. Urological complications such as ureteral obstruction and hydronephrosis can occur in the course of this pathology. This work aimed to evaluate the impact of hydronephrosis on the overall survival of patients. Patients and Methods: the records of patients followed at the ICL from January 1, 2015, to December 31, 2019, a period of 5 years, were collected. The study included patients followed for cervical cancer and who had a complete medical record: histological evidence and extension workup. Patients not followed up at ICL were not included in the study. Results: the records of 183 patients with cervical cancer during the study period were retained. The mean age was 55.3±14.1 years, with extremes of 21 and 89 years. Stages II, III, and IV accounted for 87.4% of cancers, and stages III and IV (51.3%) represented the majority of clinical stages. In univariate survival analyses, assessed from the date of cancer diagnosis, patients with hydronephrosis during their cancer had poor survival compared with those without. Patients who had no hydronephrosis had better overall survival at three years (85%) compared with those who had developed urologic complications (54%). Conclusion: hydronephrosis has a negative effect on the prognosis of cervical cancer, and indeed, it significantly decreases the overall survival of patients with cervical cancer. Therefore, it is essential to screen them systematically to treat them as effectively as possible.},
 year = {2022}
}

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