Mercury (Hg) pollution is featuring as one of the major threat for marine ecosystem, biota and human health. Thereby, the objective of the current study was to evaluate the effect of environmentally relevant concentrations of mercury on oxidative stress, enzymatic and non-enzymatic antioxidant defenses and metallothionein levels in the longitudinal muscle of sea cucumber Holothuria forskali. With this purpose, sea cucumber were exposed to graded concentrations of mercury chloride HgCl2 (40, 80 and 160 µg L-1) for 96 h under controlled conditions. Our findings revealed that Hg burden in the longitudinal muscle tended to increase with increasing HgCl2 concentrations. The Hg exposure promoted muscular oxidative stress as evidenced by the increased levels of malondialdehyde (MDA), advanced oxidation protein product (AOPP) and metallothionein (MT) of treated animals compared with controls. Additionally, significant increases in the activities of the enzymatic (glutathione peroxidase (GPx), superoxide dismutase (SOD) and catalase (CAT)) and non-enzymatic (non-protein thiol (NPSH) and glutathione (GSH)) antioxidants were also observed in all treated groups. Overall, this study proved that mercury is able to produce deleterious effects even at the lowest environmentally-realistic concentration in the Holothuria forskali longitudinal muscle which may be considered as a target tissue of mercury accumulation in holothurian.
| Published in | International Journal of Ecotoxicology and Ecobiology (Volume 5, Issue 4) |
| DOI | 10.11648/j.ijee.20200504.13 |
| Page(s) | 54-60 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2020. Published by Science Publishing Group |
Holothuria forskali, Mercuric Chloride (HgCl2), Longitudinal Muscle Hg Burden, Enzymatic and Non-enzymatic Antioxidant
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APA Style
Imen Rabeh, Khaoula Telahigue, Tarek Hajji, Chaima Fouzai, Safa Bejaoui, et al. (2020). Influence of Mercury Exposure on Oxidative Stress Biomarkers in Longitudinal Muscle of Holothuria forskali. International Journal of Ecotoxicology and Ecobiology, 5(4), 54-60. https://doi.org/10.11648/j.ijee.20200504.13
ACS Style
Imen Rabeh; Khaoula Telahigue; Tarek Hajji; Chaima Fouzai; Safa Bejaoui, et al. Influence of Mercury Exposure on Oxidative Stress Biomarkers in Longitudinal Muscle of Holothuria forskali. Int. J. Ecotoxicol. Ecobiol. 2020, 5(4), 54-60. doi: 10.11648/j.ijee.20200504.13
AMA Style
Imen Rabeh, Khaoula Telahigue, Tarek Hajji, Chaima Fouzai, Safa Bejaoui, et al. Influence of Mercury Exposure on Oxidative Stress Biomarkers in Longitudinal Muscle of Holothuria forskali. Int J Ecotoxicol Ecobiol. 2020;5(4):54-60. doi: 10.11648/j.ijee.20200504.13
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Download@article{10.11648/j.ijee.20200504.13,
author = {Imen Rabeh and Khaoula Telahigue and Tarek Hajji and Chaima Fouzai and Safa Bejaoui and Lassaad Chouba and Mhamed El Cafsi and Nejla Soudani},
title = {Influence of Mercury Exposure on Oxidative Stress Biomarkers in Longitudinal Muscle of Holothuria forskali},
journal = {International Journal of Ecotoxicology and Ecobiology},
volume = {5},
number = {4},
pages = {54-60},
doi = {10.11648/j.ijee.20200504.13},
url = {https://doi.org/10.11648/j.ijee.20200504.13},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijee.20200504.13},
abstract = {Mercury (Hg) pollution is featuring as one of the major threat for marine ecosystem, biota and human health. Thereby, the objective of the current study was to evaluate the effect of environmentally relevant concentrations of mercury on oxidative stress, enzymatic and non-enzymatic antioxidant defenses and metallothionein levels in the longitudinal muscle of sea cucumber Holothuria forskali. With this purpose, sea cucumber were exposed to graded concentrations of mercury chloride HgCl2 (40, 80 and 160 µg L-1) for 96 h under controlled conditions. Our findings revealed that Hg burden in the longitudinal muscle tended to increase with increasing HgCl2 concentrations. The Hg exposure promoted muscular oxidative stress as evidenced by the increased levels of malondialdehyde (MDA), advanced oxidation protein product (AOPP) and metallothionein (MT) of treated animals compared with controls. Additionally, significant increases in the activities of the enzymatic (glutathione peroxidase (GPx), superoxide dismutase (SOD) and catalase (CAT)) and non-enzymatic (non-protein thiol (NPSH) and glutathione (GSH)) antioxidants were also observed in all treated groups. Overall, this study proved that mercury is able to produce deleterious effects even at the lowest environmentally-realistic concentration in the Holothuria forskali longitudinal muscle which may be considered as a target tissue of mercury accumulation in holothurian.},
year = {2020}
}
TY - JOUR T1 - Influence of Mercury Exposure on Oxidative Stress Biomarkers in Longitudinal Muscle of Holothuria forskali AU - Imen Rabeh AU - Khaoula Telahigue AU - Tarek Hajji AU - Chaima Fouzai AU - Safa Bejaoui AU - Lassaad Chouba AU - Mhamed El Cafsi AU - Nejla Soudani Y1 - 2020/12/16 PY - 2020 N1 - https://doi.org/10.11648/j.ijee.20200504.13 DO - 10.11648/j.ijee.20200504.13 T2 - International Journal of Ecotoxicology and Ecobiology JF - International Journal of Ecotoxicology and Ecobiology JO - International Journal of Ecotoxicology and Ecobiology SP - 54 EP - 60 PB - Science Publishing Group SN - 2575-1735 UR - https://doi.org/10.11648/j.ijee.20200504.13 AB - Mercury (Hg) pollution is featuring as one of the major threat for marine ecosystem, biota and human health. Thereby, the objective of the current study was to evaluate the effect of environmentally relevant concentrations of mercury on oxidative stress, enzymatic and non-enzymatic antioxidant defenses and metallothionein levels in the longitudinal muscle of sea cucumber Holothuria forskali. With this purpose, sea cucumber were exposed to graded concentrations of mercury chloride HgCl2 (40, 80 and 160 µg L-1) for 96 h under controlled conditions. Our findings revealed that Hg burden in the longitudinal muscle tended to increase with increasing HgCl2 concentrations. The Hg exposure promoted muscular oxidative stress as evidenced by the increased levels of malondialdehyde (MDA), advanced oxidation protein product (AOPP) and metallothionein (MT) of treated animals compared with controls. Additionally, significant increases in the activities of the enzymatic (glutathione peroxidase (GPx), superoxide dismutase (SOD) and catalase (CAT)) and non-enzymatic (non-protein thiol (NPSH) and glutathione (GSH)) antioxidants were also observed in all treated groups. Overall, this study proved that mercury is able to produce deleterious effects even at the lowest environmentally-realistic concentration in the Holothuria forskali longitudinal muscle which may be considered as a target tissue of mercury accumulation in holothurian. VL - 5 IS - 4 ER -
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