Chicken growth hormone (cGH) gene, one of the candidate genes for economic traits that control body weight and fat deposition, is associated with regulating both growth-axon patterning and metabolism. The growth hormone gene located on the chromosome 2 it enhances and encodes growth hormones as well as protein which are responsible for regulating of growth and development of body tissues. Growth hormone gene as economically very important because of growth rate, efficiency of feeds, body weight, and also for egg production. It also used for the Genetic Engineering for production of desirable GH- related genes. Genomic DNA from four different chicken breeds were screened for single nucleotide polymorphisms (SNPs) of cGH gene by denaturing high-performance liquid chromatography, as well as sequencing. SNPs and Nucleotide Diversity of the cGH Gene PCR amplification of 700 bp region from each individual from two chicken breeds was performed, which covered partial exons/introns encoding fragments corresponding to the investigated translated peptide. An average of one SNP was found every 86 bp, with a total of eight SNPs discovered. Nine SNPs were in introns, while 4 and one each was in the 5'UTR and 3'UTR respectively of these, five of them (01 from GWAS linkage signals) had significant associations.
| Published in | International Journal of Genetics and Genomics (Volume 12, Issue 3) |
| DOI | 10.11648/j.ijgg.20241203.13 |
| Page(s) | 68-73 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
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Copyright © The Author(s), 2024. Published by Science Publishing Group |
Animal Husbandry, Desi Chickens, Fayoumi Chicken, Phenotype, Plumage
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APA Style
Jakhrani, S. A., Ujan, J. A., Ujjan, S. A., Ghumro, S. (2024). Diversity of the Chicken Growth Hormone Gene and Effects on Growth Desi and Fayoumi Chicken Traits at District Kashmore, Sindh-Pakistan. International Journal of Genetics and Genomics, 12(3), 68-73. https://doi.org/10.11648/j.ijgg.20241203.13
ACS Style
Jakhrani, S. A.; Ujan, J. A.; Ujjan, S. A.; Ghumro, S. Diversity of the Chicken Growth Hormone Gene and Effects on Growth Desi and Fayoumi Chicken Traits at District Kashmore, Sindh-Pakistan. Int. J. Genet. Genomics 2024, 12(3), 68-73. doi: 10.11648/j.ijgg.20241203.13
AMA Style
Jakhrani SA, Ujan JA, Ujjan SA, Ghumro S. Diversity of the Chicken Growth Hormone Gene and Effects on Growth Desi and Fayoumi Chicken Traits at District Kashmore, Sindh-Pakistan. Int J Genet Genomics. 2024;12(3):68-73. doi: 10.11648/j.ijgg.20241203.13
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Download@article{10.11648/j.ijgg.20241203.13,
author = {Shahid Ali Jakhrani and Javed Ahmed Ujan and Safdar Ali Ujjan and Shaista Ghumro},
title = {Diversity of the Chicken Growth Hormone Gene and Effects on Growth Desi and Fayoumi Chicken Traits at District Kashmore, Sindh-Pakistan
},
journal = {International Journal of Genetics and Genomics},
volume = {12},
number = {3},
pages = {68-73},
doi = {10.11648/j.ijgg.20241203.13},
url = {https://doi.org/10.11648/j.ijgg.20241203.13},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijgg.20241203.13},
abstract = {Chicken growth hormone (cGH) gene, one of the candidate genes for economic traits that control body weight and fat deposition, is associated with regulating both growth-axon patterning and metabolism. The growth hormone gene located on the chromosome 2 it enhances and encodes growth hormones as well as protein which are responsible for regulating of growth and development of body tissues. Growth hormone gene as economically very important because of growth rate, efficiency of feeds, body weight, and also for egg production. It also used for the Genetic Engineering for production of desirable GH- related genes. Genomic DNA from four different chicken breeds were screened for single nucleotide polymorphisms (SNPs) of cGH gene by denaturing high-performance liquid chromatography, as well as sequencing. SNPs and Nucleotide Diversity of the cGH Gene PCR amplification of 700 bp region from each individual from two chicken breeds was performed, which covered partial exons/introns encoding fragments corresponding to the investigated translated peptide. An average of one SNP was found every 86 bp, with a total of eight SNPs discovered. Nine SNPs were in introns, while 4 and one each was in the 5'UTR and 3'UTR respectively of these, five of them (01 from GWAS linkage signals) had significant associations.
},
year = {2024}
}
TY - JOUR T1 - Diversity of the Chicken Growth Hormone Gene and Effects on Growth Desi and Fayoumi Chicken Traits at District Kashmore, Sindh-Pakistan AU - Shahid Ali Jakhrani AU - Javed Ahmed Ujan AU - Safdar Ali Ujjan AU - Shaista Ghumro Y1 - 2024/10/29 PY - 2024 N1 - https://doi.org/10.11648/j.ijgg.20241203.13 DO - 10.11648/j.ijgg.20241203.13 T2 - International Journal of Genetics and Genomics JF - International Journal of Genetics and Genomics JO - International Journal of Genetics and Genomics SP - 68 EP - 73 PB - Science Publishing Group SN - 2376-7359 UR - https://doi.org/10.11648/j.ijgg.20241203.13 AB - Chicken growth hormone (cGH) gene, one of the candidate genes for economic traits that control body weight and fat deposition, is associated with regulating both growth-axon patterning and metabolism. The growth hormone gene located on the chromosome 2 it enhances and encodes growth hormones as well as protein which are responsible for regulating of growth and development of body tissues. Growth hormone gene as economically very important because of growth rate, efficiency of feeds, body weight, and also for egg production. It also used for the Genetic Engineering for production of desirable GH- related genes. Genomic DNA from four different chicken breeds were screened for single nucleotide polymorphisms (SNPs) of cGH gene by denaturing high-performance liquid chromatography, as well as sequencing. SNPs and Nucleotide Diversity of the cGH Gene PCR amplification of 700 bp region from each individual from two chicken breeds was performed, which covered partial exons/introns encoding fragments corresponding to the investigated translated peptide. An average of one SNP was found every 86 bp, with a total of eight SNPs discovered. Nine SNPs were in introns, while 4 and one each was in the 5'UTR and 3'UTR respectively of these, five of them (01 from GWAS linkage signals) had significant associations. VL - 12 IS - 3 ER -
Department of Zoology, Faculty of Natural Sciences, Shah Abdul Latif University KhairpurMirs, Sindh, Pakistan
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