International Journal of Genetics and Genomics

Volume 12, Issue 3, September 2024

  • Research Article

    CRISPR-Cas9 Gene Editing Therapy, a Curative Hope for Sickle Cell in Nigeria, West Africa

    Babatunde Ibrahim Olowu*, Ahmed Saheed Olaide, Oluwaloni Bolaji Tinubu

    Issue: Volume 12, Issue 3, September 2024
    Pages: 48-53
    Received: 24 April 2024
    Accepted: 20 June 2024
    Published: 15 July 2024
    Downloads:
    Views:
    Abstract: Sickle cell anaemia is one of the haemoglobin abnormalities resulting from a genetic mutation— it is caused by inheriting two faulty genes that result in an abnormal substitution of glutamate for valine on the beta chain of haemoglobin, which causes haemoglobin molecules to stick together. According to a World Health Organization (WHO) report, 20 o... Show More
  • Research Article

    Combining Ability, Heterosis and Potence Ratio for Yield and Yield Components in Korean Double-Haploid, Progenies and Improved Rice Varieties in Nigeria

    Ogba Chinonyelum Somtochukwu, Efisue Andrew Abiodun*

    Issue: Volume 12, Issue 3, September 2024
    Pages: 54-67
    Received: 12 June 2024
    Accepted: 9 July 2024
    Published: 31 July 2024
    Downloads:
    Views:
    Abstract: Rice is the most widely consumed staple crop in Africa and consumption continues to grow at a rapid pace with increasing population. Success in breeding programs are largely dependent on the genetic diversity of a crop. Genetic variability occurs due to genetic differences in individuals within a given population, which is the basis of plant breedi... Show More
  • Research Article

    Diversity of the Chicken Growth Hormone Gene and Effects on Growth Desi and Fayoumi Chicken Traits at District Kashmore, Sindh-Pakistan

    Shahid Ali Jakhrani*, Javed Ahmed Ujan, Safdar Ali Ujjan, Shaista Ghumro

    Issue: Volume 12, Issue 3, September 2024
    Pages: 68-73
    Received: 21 April 2024
    Accepted: 8 July 2024
    Published: 29 October 2024
    Downloads:
    Views:
    Abstract: Chicken growth hormone (cGH) gene, one of the candidate genes for economic traits that control body weight and fat deposition, is associated with regulating both growth-axon patterning and metabolism. The growth hormone gene located on the chromosome 2 it enhances and encodes growth hormones as well as protein which are responsible for regulating o... Show More