Archive:: International Journal of Genetics and Genomics:: Science Publishing Group

Volume 5, Issue 1, February 2017

Persistent Circulating Immune Complexes: Potential Source of Epimutation and Cancer Poor Prognosis

Michael Chukwudi Ezeani, Charles Chinedum Onyenekwe, Samuel Chukwuemeka Meludu

Issue: Volume 5, Issue 1, February 2017

Pages: 1-13

Received: 13 December 2016

Accepted: 27 December 2016

Published: 29 January 2017

DOI: 10.11648/j.ijgg.20170501.11

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Abstract: Estimation of serum level of circulating immune complexes and its use for monitoring treatments have been carried out extensively in various disease conditions including autoimmune diseases and cancer, but little or no work has considered persistent circulation of immune complexes consequent to physiological anomalies that could mediate epimutation... Show More

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A Reduced Interval of Chromosome 9p21 Locus is Associated with Ischemic Stroke in Chinese Northern Han Population

Shuo Li, Yu-Ming Xu, Hong Zheng, Edward Randell, Hai-Zheng Wang, Jianxun Cui, Guang Sun, Guangju Zhai, Fei-Yu Han, Ya-Gang Xie

Issue: Volume 5, Issue 1, February 2017

Pages: 14-18

Received: 6 March 2017

Published: 10 March 2017

DOI: 10.11648/j.ijgg.20170501.12

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Abstract: The 9p21 locus, a strong risk locus for coronary arterial disease, has been also associated with other cardiovascular disease including ischemic stroke (IS) in Caucasians. However, the association between 9p21 locus and IS in Chinese Han population is still debatable because of ambiguous results reported previously. Genetic heterogeneity between So... Show More

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