International Journal of Genetics and Genomics

Archive

Volume 4, Issue 4, August 2016

  • CTLA-4 Gene Polymorphism in Women with Idiopathic Recurrent Pregnancy Loss

    Eman N. Helles, Mohammed J. Ashour, Fadel A. Sharif

    Issue: Volume 4, Issue 4, August 2016
    Pages: 31-35
    Received: 8 August 2016
    Accepted: 17 August 2016
    Published: 5 September 2016
    DOI: 10.11648/j.ijgg.20160404.11
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    Abstract: Cytotoxic T lymphocyte associated antigen-4 (CTLA-4) is considered as a negative regulator of T cell activation and its role in maintaining immune tolerance is well established. The present case-control study aimed to investigate the CTLA-4 +49 A/G, -1661 A/G, -318 C/T and -1722 T/C single nucleotide polymorphisms (SNPs) and predisposition to recur... Show More
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  • Virulence Factors of E. coli ST131 and Its H30 and H30Rx Subclones Among Extended-Spectrum Beta-Lactamase Producing Isolates

    Khadega Yahya Abdullah AL-hetar, Nanjaiah Lakshmidevi

    Issue: Volume 4, Issue 4, August 2016
    Pages: 36-39
    Received: 17 August 2016
    Accepted: 26 August 2016
    Published: 18 September 2016
    DOI: 10.11648/j.ijgg.20160404.12
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    Abstract: Escherichia coli sequence type 131 (ST131) is a pandemic clone causing predominantly community and hospital-onset antimicrobial-resistant infections. Recently, H30-Rx subclone of E. coli has been disseminated among ST131 strains in combination with beta lactamase subtype CTX-15that may play a role in the prevalence of antibiotic resistance among E.... Show More
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