Acute lower respiratory tract infection is a common disease among the under five children. The purpose of the present study was to see the frequency and distribution of viruses causing acute lower respiratory tract infection among under-five children. This cross-sectional study was conducted in the Department of Virology at Bangabandhu Sheikh Mujib Medical University, Dhaka from July 2002 to June 2003 for a period of one year. The children with the age group of below five (5) years presented with the clinical manifestations of acute lower respiratory tract infection (ALRI) who were visited or were admitted to Dhaka Medical College Hospital (DMCH), Dhaka were selected as the study population. Nasopharyngeal aspirates were collected. Viruses were detected by cell line culture and direct immunofluorescence method. The study was carried out among 100 children aged from newborn to 60 months with acute lower respiratory tract infection (ALRI). The highest rate (47.6%) of isolation was obtained among children between 0 to 5 months of age followed by 6 to 12 months of age group (23.80%). There was a significant reduction in the number of cases in older children in 25 to 60 months of age group. Out of 57 patients, 12 were positive for respiratory viruses in the case of a male, while 43 of specimens from a female, 9 were positive. The most common virus isolated from the under-five children was a respiratory syncytial virus which was 20(95.2%). Adenovirus was isolated in only 1(4.8%) case. No other viruses were found in this study. In conclusion, the most common virus isolated from the under-five children is respiratory syncytial virus. Adenovirus is also found.
| Published in | International Journal of Infectious Diseases and Therapy (Volume 2, Issue 2) |
| DOI | 10.11648/j.ijidt.20170202.13 |
| Page(s) | 40-43 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Viruses, Acute Lower Respiratory Tract Infection, Under Five Children
| [1] | Rahman M, Huq F, Sack DA, Butler T, Azad AK, Alam A, Nahar N, Islam M. Acute lower respiratory tract infections in hospitalized patients with diarrhea in Dhaka, Bangladesh. Rev Infect Dis I990; 12: 899-906. |
| [2] | Nair H, Simões EA, Rudan I, Gessner BD, Azziz-Baumgartner E, Zhang JS, Feikin DR, Mackenzie GA, Moiïsi JC, Roca A, Baggett HC. The global and regional burden of hospital admissions for severe acute lower respiratory infections in young children in 2010: a systematic analysis. Lancet 2013; 381 (9875): 1380-90 . |
| [3] | Mazur NI, Martinón-Torres F, Baraldi E, Fauroux B, Greenough A, Heikkinen T, Manzoni P, Mejias A, Nair H, Papadopoulos NG, Polack FP. Lower respiratory tract infection caused by the respiratory syncytial virus: current management and new therapeutics. Lancet Respiratory Med 2015; 3 (11): 888-900. |
| [4] | Nasreen S, Luby SP, Brooks WA, Homaira N, Al Mamun A, Bhuiyan MU, Rahman M, Ahmed D, Abedin J, Rahman M, Alamgir AS. Population-based incidence of severe acute respiratory virus infections among children aged< 5 years in rural Bangladesh, June–October 2010. PloS one 2014; 9 (2): e89978. |
| [5] | Rudan I, Boschi-Pinto C, Biloglav Z, Mulholland K, Campbell H. Epidemiology and etiology of childhood pneumonia. Bulletin World Health Organization 2008; 86: 408–416. |
| [6] | National Institute of Population Research and Training (NIPORT), Mitra and Associates, Macro International. Bangladesh Demographic and Health Survey, 2007; Dhaka, Bangladesh and Calverton, Maryland, USA: National Institute of Population Research and Training, Mitra and Associates, and Macro International, 2009. |
| [7] | Walker CL, Rudan I, Liu L, Nair H, Theodoratou E, Bhutta ZA, O'Brien KL, Campbell H, Black RE. Global burden of childhood pneumonia and diarrhea. Lancet 2013; 381 (9875): 1405-16. |
| [8] | Landry ML, Ferguson D. SimulFluor respiratory screen specimens by immunofluorescence staining for rapid detection of multiple respiratory viruses in the clinical specimen. J Clin Microbiol 2000; 35: 708-711. |
| [9] | Halstead DC, Todd S, Fritch G. Evaluation of five methods for respiratory syncytial virus detection. J Clin Microbiol 1990; 28: 1021-1025. |
| [10] | Chattopadhyay D, Chatterjee R, Anand VK, Kumari S, Patwari AK. Lower respiratory tract infection in hospitalized children due to the respiratory syncytial (RS) virus during a suspected epidemic period of RS virus in Delhi. J Trop Paediatr 1992; 38; 68-73. |
| [11] | Lukšić I, Kearns PK, Scott F, Rudan I, Campbell H, Nair H. Viral etiology of hospitalized acute lower respiratory infections in children under 5 years of age–a systematic review and meta-analysis. Croatian Med J 2013; 54 (2): 122-34. |
| [12] | Jackson S, Mathews KH, Pulanić D, Falconer R, Rudan I, Campbell H, Nair H. Risk factors for severe acute lower respiratory infections in children–a systematic review and meta-analysis. Croatian Med J 2013; 54 (2): 110-21. |
| [13] | Fan J, Henrickson KJ, Savatski LL. Rapid simultaneous diagnosis of infections with respiratory syncytial viruses A and B, influenza viruses A and B, human parainfluenza virus types 1,2, and 3 by multiplex quantitative reverse transcription-polymerase chain reaction -enzyme hybridization assay (Hexaplex). Clin Infect Dis 1998; 26: 1397-1402. |
| [14] | Maitreyi RS, Kabra SK, Ghosh M, Dar L, Seth P, Prasad AK. Rapid detection methods for diagnosis of acute lower respiratory tract infections in young children due to respiratory syncytial virus. Indian J Med Microbiol 1999; 17 (1): 10-13. |
| [15] | Hijazi Z, Picasa A. Gharbawy FE, Chugh EssaTD S, Shazli AE, SalamRAE. Acute lower respiratory tract infections in children in Kuwait. Ann of Trop Paediatr 1997; 17: 127-134. |
| [16] | Forgie IM, Campbell H, Evans NL, Leinonen M, Neil KPO, Saikku P, Whittle HC, Greenwood BM. Etiology of acute lower respiratory tract infections in children in a rural community in the Gambia. Pediatr Infect Dis J 1992; ll: 446-73. |
| [17] | Guerrier G, Goyette S, Chheng ET, Rampart B, Brand L, Te V, Try PL, Sarah R, Cavailler P, Mayaud C, Guillard B. Acute viral lower respiratory tract infections in Cambodian children: clinical and epidemiologic characteristics. Pediatric Infect Dis J 2013; 32 (1): e8-13. |
| [18] | Feng L, Li Z, Zhao S, Nair H, Lai S, Xu W, Li M, Wu J, Ren L, Liu W, Yuan Z. Viral etiologies of hospitalized acute lower respiratory infection patients in China, 2009-2013. PloS one 2014; 9 (6): e99419. |
| [19] | Hacimustafaoglu M, Çelebi S, Bozdemir SE, Özgür T, Özcan İ, Güray A, Cakir D. RSV frequency in children below 2 years hospitalized for lower respiratory tract infections. Turkish J Pediatric 2013; 55 (2): 130. |
APA Style
Rashida Akter Khanam, Md. Nazrul Islam, Shahina Tabassum, Ahmed Sharif, Md. Abdullah Yusuf, et al. (2017). Frequency and Distribution of Viruses Causing Acute Lower Respiratory Tract Infection Among Under-Five Children in Dhaka City. International Journal of Infectious Diseases and Therapy, 2(2), 40-43. https://doi.org/10.11648/j.ijidt.20170202.13
ACS Style
Rashida Akter Khanam; Md. Nazrul Islam; Shahina Tabassum; Ahmed Sharif; Md. Abdullah Yusuf, et al. Frequency and Distribution of Viruses Causing Acute Lower Respiratory Tract Infection Among Under-Five Children in Dhaka City. Int. J. Infect. Dis. Ther. 2017, 2(2), 40-43. doi: 10.11648/j.ijidt.20170202.13
AMA Style
Rashida Akter Khanam, Md. Nazrul Islam, Shahina Tabassum, Ahmed Sharif, Md. Abdullah Yusuf, et al. Frequency and Distribution of Viruses Causing Acute Lower Respiratory Tract Infection Among Under-Five Children in Dhaka City. Int J Infect Dis Ther. 2017;2(2):40-43. doi: 10.11648/j.ijidt.20170202.13
Share This Article
Twitter
Linked In
Facebook
Copy
Download@article{10.11648/j.ijidt.20170202.13,
author = {Rashida Akter Khanam and Md. Nazrul Islam and Shahina Tabassum and Ahmed Sharif and Md. Abdullah Yusuf and Mohammad Mashudur Rahman},
title = {Frequency and Distribution of Viruses Causing Acute Lower Respiratory Tract Infection Among Under-Five Children in Dhaka City},
journal = {International Journal of Infectious Diseases and Therapy},
volume = {2},
number = {2},
pages = {40-43},
doi = {10.11648/j.ijidt.20170202.13},
url = {https://doi.org/10.11648/j.ijidt.20170202.13},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijidt.20170202.13},
abstract = {Acute lower respiratory tract infection is a common disease among the under five children. The purpose of the present study was to see the frequency and distribution of viruses causing acute lower respiratory tract infection among under-five children. This cross-sectional study was conducted in the Department of Virology at Bangabandhu Sheikh Mujib Medical University, Dhaka from July 2002 to June 2003 for a period of one year. The children with the age group of below five (5) years presented with the clinical manifestations of acute lower respiratory tract infection (ALRI) who were visited or were admitted to Dhaka Medical College Hospital (DMCH), Dhaka were selected as the study population. Nasopharyngeal aspirates were collected. Viruses were detected by cell line culture and direct immunofluorescence method. The study was carried out among 100 children aged from newborn to 60 months with acute lower respiratory tract infection (ALRI). The highest rate (47.6%) of isolation was obtained among children between 0 to 5 months of age followed by 6 to 12 months of age group (23.80%). There was a significant reduction in the number of cases in older children in 25 to 60 months of age group. Out of 57 patients, 12 were positive for respiratory viruses in the case of a male, while 43 of specimens from a female, 9 were positive. The most common virus isolated from the under-five children was a respiratory syncytial virus which was 20(95.2%). Adenovirus was isolated in only 1(4.8%) case. No other viruses were found in this study. In conclusion, the most common virus isolated from the under-five children is respiratory syncytial virus. Adenovirus is also found.},
year = {2017}
}
TY - JOUR T1 - Frequency and Distribution of Viruses Causing Acute Lower Respiratory Tract Infection Among Under-Five Children in Dhaka City AU - Rashida Akter Khanam AU - Md. Nazrul Islam AU - Shahina Tabassum AU - Ahmed Sharif AU - Md. Abdullah Yusuf AU - Mohammad Mashudur Rahman Y1 - 2017/03/09 PY - 2017 N1 - https://doi.org/10.11648/j.ijidt.20170202.13 DO - 10.11648/j.ijidt.20170202.13 T2 - International Journal of Infectious Diseases and Therapy JF - International Journal of Infectious Diseases and Therapy JO - International Journal of Infectious Diseases and Therapy SP - 40 EP - 43 PB - Science Publishing Group SN - 2578-966X UR - https://doi.org/10.11648/j.ijidt.20170202.13 AB - Acute lower respiratory tract infection is a common disease among the under five children. The purpose of the present study was to see the frequency and distribution of viruses causing acute lower respiratory tract infection among under-five children. This cross-sectional study was conducted in the Department of Virology at Bangabandhu Sheikh Mujib Medical University, Dhaka from July 2002 to June 2003 for a period of one year. The children with the age group of below five (5) years presented with the clinical manifestations of acute lower respiratory tract infection (ALRI) who were visited or were admitted to Dhaka Medical College Hospital (DMCH), Dhaka were selected as the study population. Nasopharyngeal aspirates were collected. Viruses were detected by cell line culture and direct immunofluorescence method. The study was carried out among 100 children aged from newborn to 60 months with acute lower respiratory tract infection (ALRI). The highest rate (47.6%) of isolation was obtained among children between 0 to 5 months of age followed by 6 to 12 months of age group (23.80%). There was a significant reduction in the number of cases in older children in 25 to 60 months of age group. Out of 57 patients, 12 were positive for respiratory viruses in the case of a male, while 43 of specimens from a female, 9 were positive. The most common virus isolated from the under-five children was a respiratory syncytial virus which was 20(95.2%). Adenovirus was isolated in only 1(4.8%) case. No other viruses were found in this study. In conclusion, the most common virus isolated from the under-five children is respiratory syncytial virus. Adenovirus is also found. VL - 2 IS - 2 ER -
Information
Email: