In this report we describe a patient with sub-acute bacteremic brucellosis complicated by Brucella parotitis with abscess formation as a paradoxical reaction on therapy. A 69 years old male known to have Warthin’s tumor of parotid glands two years before his presentation. He presented with generalized ill-health, body-aches and feeling of further enlargement of his previous swellings at jaw angles for a few weeks. He admitted unpasteurized camels’ milk ingestion. Brucellosis was suspected and proven by a positive blood culture. 10 days after starting anti-brucellosis therapy, he reported back with bilateral parotid abscesses. Patient was diagnosed as sub-acute bacteremic brucellosis with brucella parotitis and abscess formation. The interval enlargement of parotid swellings and abscess formation 10 days after initiation of therapy is explained by paradoxical inflammatory reaction following response to therapy.
| Published in | International Journal of Infectious Diseases and Therapy (Volume 2, Issue 2) |
| DOI | 10.11648/j.ijidt.20170202.14 |
| Page(s) | 44-47 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Brucella Parotitis, Paradoxical Reaction, Brucella Abscess
| [1] | Sara Alsubaie, Maha Almuneef, Mohammed Alshaalan, Hanan Balkhy, Essam Albanyan, Sulaiman Alola, Badria Alotaibi, Ziad A. Memish. Acute brucellosis in Saudi families: Relationship between brucella serology and clinical symptoms. International Journal of Infectious Diseases (2005) 9, 218—224. |
| [2] | Horasan, Elif Sahin; Vaysoglu, Yusuf; Ünal, Murat; Uguz, Mustafa; Kaya, Ali. Brucella melitensis Infection Within Warthin Tumor of the Parotid Gland. Journal of Craniofacial Surgery. 22 (5): 1899-1901, September 2011. |
| [3] | Colin Stewart Brown, Colette Joanne Smith, Ronan Angus MacCormick Breen, Lawrence Peter Ormerod, Rahul Mittal, Marie Fisk, Heather June Milburn, Nicholas Martin Price, Graham Henry Bothamley, Marc Caeroos Isaac Lipman. Determinants of treatment-related paradoxical reactions during antituberculosis therapy: a case control study. BMC Infectious Diseases (2016) 16: 479. |
| [4] | Ronaldo C. B. Gryschek, Ricardo M. Pereira, Adriana Kono, Rosely A. Patzina, Antonia T. Tresoldi, Maria A. Shikanai-Yasuda, Gil Benard. Paradoxical Reaction to Treatment in 2 Patients with Severe Acute Paracoccidioidomycosis: A Previously Unreported Complication and Its Management with Corticosteroids. CID 2010: 50 (15 May). |
| [5] | N. Deborah Friedman, Anthony H. McDonald, Michael E. Robson, Daniel P. O’Brien. Corticosteroid Use for Paradoxical Reactions during Antibiotic Treatment for Mycobacterium ulcerans. Neglected Tropical Diseases. 2 September 2012. Volume 6. Issue 9. |
| [6] | Béraud G, Desbois N, Coyo C, Quist D, Rozé B, Savorit L, Cabié A. Paradoxical response preceding control of Scedosporium apiospermum mycetoma with posaconazole treatment. Infect Dis (Lond). 2015; 47 (11): 830-3. |
| [7] | Vermiglio F, Stassi G, Finocchiaro MD, Trimarchi F. Thyroiditis due to Bruce lla melitensis. J Endocrinol Invest. 1995 Apr; 18 (4): 308-10. |
| [8] | Varona JF, Guerra JM, Guillén V, Guillén S, Menassa A, Palenque E. Isolated cervical lymphadenopathy as unique manifestation of Brucellosis. Scand J Infect Dis. 2002; 34 (7): 538-40. |
| [9] | Kaya O, Akcam FZ, Uyar C, Tuz M, Kapucuoglu N. Neck abscess caused by Brucella sp. Infection. 2007 Dec; 35 (6): 479-80. |
| [10] | Karsen H, Tekin Koruk S, Duygu F, Yapici K, Kati M. Review of 17 cases of neurobrucellosis: clinical manifestations, diagnosis, and management. Arch Iran Med. 2012 Aug; 15 (8): 491-4. |
| [11] | Montazeri M, Sadeghi K, Khalili H, Davoudi S. Fever and psychosis as an early presentation of Brucella-associated meningoencephalitis: a case report. Med Princ Pract. 2013; 22 (5): 506-9. |
| [12] | Mete B, Kurt C, Yilmaz MH, Ertan G, Ozaras R, Mert A, Tabak F, Ozturk R. Vertebral osteomyelitis: eight years' experience of 100 cases. Rheumatol Int. 2012 Nov; 32 (11): 3591-7. |
| [13] | K F Tabbara and H al-Kassimi. Ocular brucellosis. Br J Ophthalmol. 1990 Apr; 74 (4): 249–250. |
| [14] | Gul HC, Akyol I, Sen B, Adayener C, Haholu A. Epididymoorchitis due to Brucella melitensis: review of 19 patients. Urol Int. 2009; 82 (2): 158-61. |
| [15] | Abid L, Frikha Z, Kallel S, Chokri Z, Ismahen B, Amin B, Hammami R, Abid D, Akrout M, Hentati M, Kammoun S. Brucella myocarditis: a rare and life-threatening cardiac complication of brucellosis. Intern Med. 2012; 51 (8): 901-4. |
| [16] | Aksakal E, Sevimli S, Gürlertop Y, Taş H. An intracardiac mobile mass: ruptured left-ventricular false tendon with big vegetation due to Brucella endocarditis. Anadolu Kardiyol Derg. 2010 Dec; 10 (6): 557-8. |
| [17] | Gürsoy S, Baskol M, Ozbakir O, Güven K, Patiroğlu T, Yücesoy M Petrella R, Young EJ. Spontaneous bacterial peritonitis due to Brucella infection. Turk J Gastroenterol. 2003 Jun; 14 (2): 145-7. |
| [18] | Petrella R, Young EJ. Acute brucella ileitis. Am J Gastroenterol. 1988 Jan; 83 (1): 80-2. |
| [19] | Al-Otaibi FE. Acute acalculus cholecystitis and hepatitis caused by Brucella melitensis. J Infect Dev Ctries. 2010 Aug 4; 4 (7): 464-7. |
| [20] | Catakli T, Arikan FI, Acar B, Dallar Y. Cutaneous vasculitis in a patient with acute brucellosis. Clin Exp Dermatol. 2009 Oct; 34 (7): e387-8. |
| [21] | French AM. Immune reconstitution inflammatory syndrome: a reappraisal. Clin Infect Dis 2009; 48: 101–107. |
APA Style
Mohamed Elkarouri, Magid A. Mohamed. (2017). Case Report: Brucella Parotitis with Abscess Formation and Paradoxical Reaction on Therapy. International Journal of Infectious Diseases and Therapy, 2(2), 44-47. https://doi.org/10.11648/j.ijidt.20170202.14
ACS Style
Mohamed Elkarouri; Magid A. Mohamed. Case Report: Brucella Parotitis with Abscess Formation and Paradoxical Reaction on Therapy. Int. J. Infect. Dis. Ther. 2017, 2(2), 44-47. doi: 10.11648/j.ijidt.20170202.14
Share This Article
Twitter
Linked In
Facebook
Copy
Download@article{10.11648/j.ijidt.20170202.14,
author = {Mohamed Elkarouri and Magid A. Mohamed},
title = {Case Report: Brucella Parotitis with Abscess Formation and Paradoxical Reaction on Therapy},
journal = {International Journal of Infectious Diseases and Therapy},
volume = {2},
number = {2},
pages = {44-47},
doi = {10.11648/j.ijidt.20170202.14},
url = {https://doi.org/10.11648/j.ijidt.20170202.14},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijidt.20170202.14},
abstract = {In this report we describe a patient with sub-acute bacteremic brucellosis complicated by Brucella parotitis with abscess formation as a paradoxical reaction on therapy. A 69 years old male known to have Warthin’s tumor of parotid glands two years before his presentation. He presented with generalized ill-health, body-aches and feeling of further enlargement of his previous swellings at jaw angles for a few weeks. He admitted unpasteurized camels’ milk ingestion. Brucellosis was suspected and proven by a positive blood culture. 10 days after starting anti-brucellosis therapy, he reported back with bilateral parotid abscesses. Patient was diagnosed as sub-acute bacteremic brucellosis with brucella parotitis and abscess formation. The interval enlargement of parotid swellings and abscess formation 10 days after initiation of therapy is explained by paradoxical inflammatory reaction following response to therapy.},
year = {2017}
}
TY - JOUR T1 - Case Report: Brucella Parotitis with Abscess Formation and Paradoxical Reaction on Therapy AU - Mohamed Elkarouri AU - Magid A. Mohamed Y1 - 2017/03/17 PY - 2017 N1 - https://doi.org/10.11648/j.ijidt.20170202.14 DO - 10.11648/j.ijidt.20170202.14 T2 - International Journal of Infectious Diseases and Therapy JF - International Journal of Infectious Diseases and Therapy JO - International Journal of Infectious Diseases and Therapy SP - 44 EP - 47 PB - Science Publishing Group SN - 2578-966X UR - https://doi.org/10.11648/j.ijidt.20170202.14 AB - In this report we describe a patient with sub-acute bacteremic brucellosis complicated by Brucella parotitis with abscess formation as a paradoxical reaction on therapy. A 69 years old male known to have Warthin’s tumor of parotid glands two years before his presentation. He presented with generalized ill-health, body-aches and feeling of further enlargement of his previous swellings at jaw angles for a few weeks. He admitted unpasteurized camels’ milk ingestion. Brucellosis was suspected and proven by a positive blood culture. 10 days after starting anti-brucellosis therapy, he reported back with bilateral parotid abscesses. Patient was diagnosed as sub-acute bacteremic brucellosis with brucella parotitis and abscess formation. The interval enlargement of parotid swellings and abscess formation 10 days after initiation of therapy is explained by paradoxical inflammatory reaction following response to therapy. VL - 2 IS - 2 ER -
Information
Email: