Utility of PCT, CRP, CD64, N/L and N% in Diagnosis of Bacterial Pneumonia in Adults: Based on the Data of 199 Bacterial Pneumonia

Jin Hua; Ma Nanzhen; Bai Haihua; Wu Nanding; Zhang Liping; Liu Guoli

doi:doi:10.11648/j.ijidt.20210602.15

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Utility of PCT, CRP, CD64, N/L and N% in Diagnosis of Bacterial Pneumonia in Adults: Based on the Data of 199 Bacterial Pneumonia

Jin Hua, Ma Nanzhen, Bai Haihua, Wu Nanding, Zhang Liping, Liu Guoli

Published in International Journal of Infectious Diseases and Therapy (Volume 6, Issue 2)

Received: 26 May 2021 Accepted: 8 June 2021 Published: 21 June 2021

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Abstract

In the background of inefficient indicators for early diagnosis of pneumonia in adults, Objective Explore the utility of PCT, CRP, CD64 and Routine Blood Parameter in diagnosis of bacterial pneumonia in adults. Methods From January 1, 2019 to December 31, 2019, 191 adult bacterial pneumonia patients diagnosed and treated in the affiliated Hospital of Inner Mongolia University for Nationalities and 99 healthy people were selected as study subjects. A total of 191 adult bacterial pneumonia patients were treated as the case group, and 99 healthy physical examination patients were treated as the control group. PCT, CRP, CD64 and blood routine test parameters were compared between them. Correlation analysis and multiple linear regression analysis were used to explore the differential factors of adult bacterial pneumonia, and ROC curve was used to analyze the effectiveness of each indicator in the differential diagnosis of adult bacterial pneumonia. Results PCT (4.95±2.462), CRP (33.53±9.342), CD64 (9.26±4.023), N/L (9.54±3.878) and N% (1.16±0.632) in the case group were significantly higher than (0.22±0.059), (3.29±1.712), (1.91±0.600), (2.66±0.665) and (0.66±0.158), those of the control group. There were no statistically significant differences in other indicators. Adult bacterial pneumonia was significantly correlated with PCT, CRP, CD64, N/L and N%, but not with WBC. PCT, CRP, CD64, N/L and N% were correlated with each other, and the correlation was statistically significant. The results of multiple linear regression model showed that PCT, CRP, CD64, N/L and N% indexes were used for the differential diagnosis of adult bacterial pneumonia are trustworthy. The AUC (95%CI) of PCT, CRP, CD64, N/L, and N% were 0.916 (0.877, 0.954), 0.995 (0.000, 1.000), 0.980 (0.962, 0.997), 0.949 (0.921, 0.976), and 0.865 (0.822, 0.908), respectively. We conclude that PCT, CRP, CD64, N/L and N% indexes are comprehensive indexes for the differential diagnosis of adult bacterial pneumonia, which have certain significance and reference value in the early identification and diagnosis of adult bacterial pneumonia.

Published in	International Journal of Infectious Diseases and Therapy (Volume 6, Issue 2)
DOI	10.11648/j.ijidt.20210602.15
Page(s)	69-74
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Bacterial Pneumonia, PCT, CRP, CD64

References

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Jin Hua, Ma Nanzhen, Bai Haihua, Wu Nanding, Zhang Liping, et al. (2021). Utility of PCT, CRP, CD64, N/L and N% in Diagnosis of Bacterial Pneumonia in Adults: Based on the Data of 199 Bacterial Pneumonia. International Journal of Infectious Diseases and Therapy, 6(2), 69-74. https://doi.org/10.11648/j.ijidt.20210602.15

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ACS Style

Jin Hua; Ma Nanzhen; Bai Haihua; Wu Nanding; Zhang Liping, et al. Utility of PCT, CRP, CD64, N/L and N% in Diagnosis of Bacterial Pneumonia in Adults: Based on the Data of 199 Bacterial Pneumonia. Int. J. Infect. Dis. Ther. 2021, 6(2), 69-74. doi: 10.11648/j.ijidt.20210602.15

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AMA Style

Jin Hua, Ma Nanzhen, Bai Haihua, Wu Nanding, Zhang Liping, et al. Utility of PCT, CRP, CD64, N/L and N% in Diagnosis of Bacterial Pneumonia in Adults: Based on the Data of 199 Bacterial Pneumonia. Int J Infect Dis Ther. 2021;6(2):69-74. doi: 10.11648/j.ijidt.20210602.15

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@article{10.11648/j.ijidt.20210602.15,
  author = {Jin Hua and Ma Nanzhen and Bai Haihua and Wu Nanding and Zhang Liping and Liu Guoli},
  title = {Utility of PCT, CRP, CD64, N/L and N% in Diagnosis of Bacterial Pneumonia in Adults: Based on the Data of 199 Bacterial Pneumonia},
  journal = {International Journal of Infectious Diseases and Therapy},
  volume = {6},
  number = {2},
  pages = {69-74},
  doi = {10.11648/j.ijidt.20210602.15},
  url = {https://doi.org/10.11648/j.ijidt.20210602.15},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijidt.20210602.15},
  abstract = {In the background of inefficient indicators for early diagnosis of pneumonia in adults, Objective Explore the utility of PCT, CRP, CD64 and Routine Blood Parameter in diagnosis of bacterial pneumonia in adults. Methods From January 1, 2019 to December 31, 2019, 191 adult bacterial pneumonia patients diagnosed and treated in the affiliated Hospital of Inner Mongolia University for Nationalities and 99 healthy people were selected as study subjects. A total of 191 adult bacterial pneumonia patients were treated as the case group, and 99 healthy physical examination patients were treated as the control group. PCT, CRP, CD64 and blood routine test parameters were compared between them. Correlation analysis and multiple linear regression analysis were used to explore the differential factors of adult bacterial pneumonia, and ROC curve was used to analyze the effectiveness of each indicator in the differential diagnosis of adult bacterial pneumonia. Results PCT (4.95±2.462), CRP (33.53±9.342), CD64 (9.26±4.023), N/L (9.54±3.878) and N% (1.16±0.632) in the case group were significantly higher than (0.22±0.059), (3.29±1.712), (1.91±0.600), (2.66±0.665) and (0.66±0.158), those of the control group. There were no statistically significant differences in other indicators. Adult bacterial pneumonia was significantly correlated with PCT, CRP, CD64, N/L and N%, but not with WBC. PCT, CRP, CD64, N/L and N% were correlated with each other, and the correlation was statistically significant. The results of multiple linear regression model showed that PCT, CRP, CD64, N/L and N% indexes were used for the differential diagnosis of adult bacterial pneumonia are trustworthy. The AUC (95%CI) of PCT, CRP, CD64, N/L, and N% were 0.916 (0.877, 0.954), 0.995 (0.000, 1.000), 0.980 (0.962, 0.997), 0.949 (0.921, 0.976), and 0.865 (0.822, 0.908), respectively. We conclude that PCT, CRP, CD64, N/L and N% indexes are comprehensive indexes for the differential diagnosis of adult bacterial pneumonia, which have certain significance and reference value in the early identification and diagnosis of adult bacterial pneumonia.},
 year = {2021}
}

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TY  - JOUR
T1  - Utility of PCT, CRP, CD64, N/L and N% in Diagnosis of Bacterial Pneumonia in Adults: Based on the Data of 199 Bacterial Pneumonia
AU  - Jin Hua
AU  - Ma Nanzhen
AU  - Bai Haihua
AU  - Wu Nanding
AU  - Zhang Liping
AU  - Liu Guoli
Y1  - 2021/06/21
PY  - 2021
N1  - https://doi.org/10.11648/j.ijidt.20210602.15
DO  - 10.11648/j.ijidt.20210602.15
T2  - International Journal of Infectious Diseases and Therapy
JF  - International Journal of Infectious Diseases and Therapy
JO  - International Journal of Infectious Diseases and Therapy
SP  - 69
EP  - 74
PB  - Science Publishing Group
SN  - 2578-966X
UR  - https://doi.org/10.11648/j.ijidt.20210602.15
AB  - In the background of inefficient indicators for early diagnosis of pneumonia in adults, Objective Explore the utility of PCT, CRP, CD64 and Routine Blood Parameter in diagnosis of bacterial pneumonia in adults. Methods From January 1, 2019 to December 31, 2019, 191 adult bacterial pneumonia patients diagnosed and treated in the affiliated Hospital of Inner Mongolia University for Nationalities and 99 healthy people were selected as study subjects. A total of 191 adult bacterial pneumonia patients were treated as the case group, and 99 healthy physical examination patients were treated as the control group. PCT, CRP, CD64 and blood routine test parameters were compared between them. Correlation analysis and multiple linear regression analysis were used to explore the differential factors of adult bacterial pneumonia, and ROC curve was used to analyze the effectiveness of each indicator in the differential diagnosis of adult bacterial pneumonia. Results PCT (4.95±2.462), CRP (33.53±9.342), CD64 (9.26±4.023), N/L (9.54±3.878) and N% (1.16±0.632) in the case group were significantly higher than (0.22±0.059), (3.29±1.712), (1.91±0.600), (2.66±0.665) and (0.66±0.158), those of the control group. There were no statistically significant differences in other indicators. Adult bacterial pneumonia was significantly correlated with PCT, CRP, CD64, N/L and N%, but not with WBC. PCT, CRP, CD64, N/L and N% were correlated with each other, and the correlation was statistically significant. The results of multiple linear regression model showed that PCT, CRP, CD64, N/L and N% indexes were used for the differential diagnosis of adult bacterial pneumonia are trustworthy. The AUC (95%CI) of PCT, CRP, CD64, N/L, and N% were 0.916 (0.877, 0.954), 0.995 (0.000, 1.000), 0.980 (0.962, 0.997), 0.949 (0.921, 0.976), and 0.865 (0.822, 0.908), respectively. We conclude that PCT, CRP, CD64, N/L and N% indexes are comprehensive indexes for the differential diagnosis of adult bacterial pneumonia, which have certain significance and reference value in the early identification and diagnosis of adult bacterial pneumonia.
VL  - 6
IS  - 2
ER  -

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Author Information

Jin Hua

Inner Mongolia University for Nationalities, Affiliated Hospital, Nationalities, Tongliao, China
Ma Nanzhen

Anhui Medical University, Affiliated Hospital, Hefei, China
Bai Haihua

Inner Mongolia University for Nationalities, Affiliated Hospital, Nationalities, Tongliao, China
Wu Nanding

Inner Mongolia University for Nationalities, Affiliated Hospital, Nationalities, Tongliao, China
Zhang Liping

School of Humanistic Medicine, Anhui Medical University, Hefei, China
Liu Guoli

Inner Mongolia University for Nationalities, Affiliated Hospital, Nationalities, Tongliao, China

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APA Style

Jin Hua, Ma Nanzhen, Bai Haihua, Wu Nanding, Zhang Liping, et al. (2021). Utility of PCT, CRP, CD64, N/L and N% in Diagnosis of Bacterial Pneumonia in Adults: Based on the Data of 199 Bacterial Pneumonia. International Journal of Infectious Diseases and Therapy, 6(2), 69-74. https://doi.org/10.11648/j.ijidt.20210602.15

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Jin Hua; Ma Nanzhen; Bai Haihua; Wu Nanding; Zhang Liping, et al. Utility of PCT, CRP, CD64, N/L and N% in Diagnosis of Bacterial Pneumonia in Adults: Based on the Data of 199 Bacterial Pneumonia. Int. J. Infect. Dis. Ther. 2021, 6(2), 69-74. doi: 10.11648/j.ijidt.20210602.15

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AMA Style

Jin Hua, Ma Nanzhen, Bai Haihua, Wu Nanding, Zhang Liping, et al. Utility of PCT, CRP, CD64, N/L and N% in Diagnosis of Bacterial Pneumonia in Adults: Based on the Data of 199 Bacterial Pneumonia. Int J Infect Dis Ther. 2021;6(2):69-74. doi: 10.11648/j.ijidt.20210602.15

Copy | Download

@article{10.11648/j.ijidt.20210602.15,
  author = {Jin Hua and Ma Nanzhen and Bai Haihua and Wu Nanding and Zhang Liping and Liu Guoli},
  title = {Utility of PCT, CRP, CD64, N/L and N% in Diagnosis of Bacterial Pneumonia in Adults: Based on the Data of 199 Bacterial Pneumonia},
  journal = {International Journal of Infectious Diseases and Therapy},
  volume = {6},
  number = {2},
  pages = {69-74},
  doi = {10.11648/j.ijidt.20210602.15},
  url = {https://doi.org/10.11648/j.ijidt.20210602.15},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijidt.20210602.15},
  abstract = {In the background of inefficient indicators for early diagnosis of pneumonia in adults, Objective Explore the utility of PCT, CRP, CD64 and Routine Blood Parameter in diagnosis of bacterial pneumonia in adults. Methods From January 1, 2019 to December 31, 2019, 191 adult bacterial pneumonia patients diagnosed and treated in the affiliated Hospital of Inner Mongolia University for Nationalities and 99 healthy people were selected as study subjects. A total of 191 adult bacterial pneumonia patients were treated as the case group, and 99 healthy physical examination patients were treated as the control group. PCT, CRP, CD64 and blood routine test parameters were compared between them. Correlation analysis and multiple linear regression analysis were used to explore the differential factors of adult bacterial pneumonia, and ROC curve was used to analyze the effectiveness of each indicator in the differential diagnosis of adult bacterial pneumonia. Results PCT (4.95±2.462), CRP (33.53±9.342), CD64 (9.26±4.023), N/L (9.54±3.878) and N% (1.16±0.632) in the case group were significantly higher than (0.22±0.059), (3.29±1.712), (1.91±0.600), (2.66±0.665) and (0.66±0.158), those of the control group. There were no statistically significant differences in other indicators. Adult bacterial pneumonia was significantly correlated with PCT, CRP, CD64, N/L and N%, but not with WBC. PCT, CRP, CD64, N/L and N% were correlated with each other, and the correlation was statistically significant. The results of multiple linear regression model showed that PCT, CRP, CD64, N/L and N% indexes were used for the differential diagnosis of adult bacterial pneumonia are trustworthy. The AUC (95%CI) of PCT, CRP, CD64, N/L, and N% were 0.916 (0.877, 0.954), 0.995 (0.000, 1.000), 0.980 (0.962, 0.997), 0.949 (0.921, 0.976), and 0.865 (0.822, 0.908), respectively. We conclude that PCT, CRP, CD64, N/L and N% indexes are comprehensive indexes for the differential diagnosis of adult bacterial pneumonia, which have certain significance and reference value in the early identification and diagnosis of adult bacterial pneumonia.},
 year = {2021}
}

Copy | Download

TY  - JOUR
T1  - Utility of PCT, CRP, CD64, N/L and N% in Diagnosis of Bacterial Pneumonia in Adults: Based on the Data of 199 Bacterial Pneumonia
AU  - Jin Hua
AU  - Ma Nanzhen
AU  - Bai Haihua
AU  - Wu Nanding
AU  - Zhang Liping
AU  - Liu Guoli
Y1  - 2021/06/21
PY  - 2021
N1  - https://doi.org/10.11648/j.ijidt.20210602.15
DO  - 10.11648/j.ijidt.20210602.15
T2  - International Journal of Infectious Diseases and Therapy
JF  - International Journal of Infectious Diseases and Therapy
JO  - International Journal of Infectious Diseases and Therapy
SP  - 69
EP  - 74
PB  - Science Publishing Group
SN  - 2578-966X
UR  - https://doi.org/10.11648/j.ijidt.20210602.15
AB  - In the background of inefficient indicators for early diagnosis of pneumonia in adults, Objective Explore the utility of PCT, CRP, CD64 and Routine Blood Parameter in diagnosis of bacterial pneumonia in adults. Methods From January 1, 2019 to December 31, 2019, 191 adult bacterial pneumonia patients diagnosed and treated in the affiliated Hospital of Inner Mongolia University for Nationalities and 99 healthy people were selected as study subjects. A total of 191 adult bacterial pneumonia patients were treated as the case group, and 99 healthy physical examination patients were treated as the control group. PCT, CRP, CD64 and blood routine test parameters were compared between them. Correlation analysis and multiple linear regression analysis were used to explore the differential factors of adult bacterial pneumonia, and ROC curve was used to analyze the effectiveness of each indicator in the differential diagnosis of adult bacterial pneumonia. Results PCT (4.95±2.462), CRP (33.53±9.342), CD64 (9.26±4.023), N/L (9.54±3.878) and N% (1.16±0.632) in the case group were significantly higher than (0.22±0.059), (3.29±1.712), (1.91±0.600), (2.66±0.665) and (0.66±0.158), those of the control group. There were no statistically significant differences in other indicators. Adult bacterial pneumonia was significantly correlated with PCT, CRP, CD64, N/L and N%, but not with WBC. PCT, CRP, CD64, N/L and N% were correlated with each other, and the correlation was statistically significant. The results of multiple linear regression model showed that PCT, CRP, CD64, N/L and N% indexes were used for the differential diagnosis of adult bacterial pneumonia are trustworthy. The AUC (95%CI) of PCT, CRP, CD64, N/L, and N% were 0.916 (0.877, 0.954), 0.995 (0.000, 1.000), 0.980 (0.962, 0.997), 0.949 (0.921, 0.976), and 0.865 (0.822, 0.908), respectively. We conclude that PCT, CRP, CD64, N/L and N% indexes are comprehensive indexes for the differential diagnosis of adult bacterial pneumonia, which have certain significance and reference value in the early identification and diagnosis of adult bacterial pneumonia.
VL  - 6
IS  - 2
ER  -

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