Effect of Halawa Tahinia Alone or with Ginger and Cinnamon on Sex Hormones in Adult Male Rats

Naeem M. Rabeh

doi:doi:10.11648/j.ijnfs.20160503.19

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Effect of Halawa Tahinia Alone or with Ginger and Cinnamon on Sex Hormones in Adult Male Rats

Naeem M. Rabeh

Published in International Journal of Nutrition and Food Sciences (Volume 5, Issue 3)

Received: 1 April 2016 Accepted: 11 April 2016 Published: 10 May 2016

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Abstract

This study was performed to investigate the effect of halawa tahinia alone or in combination with ginger and cinnamon on sex hormones as well as serum antioxidant levels. Thirty Wistar adult male rat were divided into five groups, control group fed on basal diet only and test groups (n=24) divided into 4 groups as follow, group (1) fed on basal diet supplemented with halawa tahinia at the level of (15%), while the other three groups were fed on basal diet supplemented with halawa tahinia (15%) and were given orally (500 mg/kg/day) dried ginger, (500 mg/kg/day) dried cinnamon, both dried ginger and cinnamon (500 mg/kg/day) respectively for 8 weeks. The results indicated that, halawa tahinia have a high nutritive value. The obtained results revealed also that, oral administration of ginger and/ or cinnamon with halawa tahinia caused a significant (p<0.05) protective effects on testes due to increasing the levels of serum total testosterones, follicular stimulating hormone (FSH) and luteinizing hormone (LH) also increasing serum total antioxidants capacity (TAC) levels with decreasing malondialdehyde (MDA) level as well as have no deleterious effects on liver functions as compared to control group. Moreover, both ginger and cinnamon administration has a synergistic effect on infertility due to their antioxidant properties. In conclusion: These results provide scientific evidence to substantiate the traditional use of cinnamon and ginger as a drink as well as Halawa tahinia in improving infertility in male rats which might be a product for their potent antioxidant properties and androgenic activities.

Published in	International Journal of Nutrition and Food Sciences (Volume 5, Issue 3)
DOI	10.11648/j.ijnfs.20160503.19
Page(s)	211-219
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2016. Published by Science Publishing Group

Keywords

Sesame Seeds, Ginger, Cinnamon, Sex Hormones, Antioxidants

References

[1]	Kamali, M.; Kashfi, F.; Baghestani, A. R.; Kashani, H.; Tavajohi, S. H. and Amirchaghmaghi, E. (2006). The epidemiologic survey on causes of infertility in patients referred to Royan Institute. Med. J. Tabriz Univ. Med. Sci., 28(1): 103-5.
[2]	Esmaeilzadeh, S.; Farsi, M. and Nazari, T. (2002). The cause of infertility frequency in the patients referring to Babol township Fatemeh Zahra Infertility Center from May 1996 to May 1998. J. Mazandaran Univ. Med. Sci., 12(35): 29-34.
[3]	Mosher, W. D. and Pratt, W. F. (1991). Fecundity and infertility in the United States: incidence and trends. J Fertil Steril; 56: 192-193.
[4]	Kahraman, T.; Issa, G. k.; Ozmen, G. and Buyukunal S. (2010). Microbiological and chemical quality of tahini halva. British Food Journal., 112 Iss (6): 608-616.
[5]	Davidson, A. (2006). The Oxford companion to food A-Z. In: Jaine T., ed. The Oxford companion to food. 2nd ed. Oxford, UK; New York, NY, USA: Oxford University Press, 1-869.
[6]	Sanja, O.; Naira, M.; Spaho, N.; Jasmina T.; Akagić A. and Džafić A. (2015). Effects of Production and Ingredients on Tahini Halvah Quality Journal of Food Science and Engineering., 5: 122-129.
[7]	Abu-Jdayil, B.; Al-Malah, K. and Asoud, H. (2002). Rheological characterization of milled sesame (tehineh). Food Hydrocolloids., 16: 55-61.
[8]	Yamani, M. I. and Isa, J. K. (2006). Microbiological quality of tehena and development of a generic HACCP plan for its production. World Journal of Agricultural Sciences., 2: 290-7.
[9]	Martinchik, AN. (2011). Nutritional value of sesame seeds. Vopr Pitan 80: 41-3.
[10]	Thompson, L.; Robb, P.; Serraino, M. and Cheung, F. (1991). Mammalian lignan production from various foods., Nutr. Cancer, 16(1): 43-52.
[11]	Yamashita, K.; Iizuka, Y.; Imai, T. and Namiki, M. (1995). Sesame seed and its lignans produce marked enhancement of Vitamin E activity in rats fed a low alpha-tocopherol diet. Lipids., 30: 1019-28.
[12]	Morimoto, S.; Akimoto, K. and Tanaka, T. (1998). Antihypertensive effect of sesamin. III. Protection against development and maintenance of hypertension in stroke-prone spontaneously hypertensive rats. Biol Pharm Bull., 21: 469-73.
[13]	Abou-Gharbia, H. A.; Shehata A. A. and Shaidi, F., (2000). Effects of processing on oxidative stability and lipid classes of sesame oil. Food Research International., 33: 331-340.
[14]	Lu, P.; Lai, B. S.; Liang, P.; Chen, Z. T. and Shun, S. Q. (2003). Antioxidation activity and protective effection of ginger oil on DNA damage in vitro. J Zhongguo Zhong Yao Za Zhi., 28: 873-875.
[15]	Grzanna, R.; Lindmark, L. and Frondoza, C. G. (2005). Ginger an herbal medicinal product with broad anti-inflammatory actions. J Med Food., 8: 125-132.
[16]	Jedlinska-Krakowska, M.; Bomba, G.; Jakubowski, K.; Rotkiewicz, T.; Jana, B. and Penkowski, A. (2006). Impact of oxidative stress and supplementation with Vitamins E and C on testes morphology in rats. J Reprod Dev., 52: 203-209.
[17]	Rajeev, K.; Gagan, G. and Narmada P. (2006). Therapy for Idiopathic Male Infertility: Rationale Versus Evidence. J of Urology; 176: 1307-1312.
[18]	Yang, H. S.; Han, D. K.; Kim, J. R. and Sim, J. C. (2006). Effects of alphatocopherol on cadmium-induced toxicity in rat testis and spermatogenesis. J Korean Med Sci., 21: 445-451.
[19]	Sekiwa, Y.; Kubota, K. and Kobayashi, A. (2000). Isolation of novel glucosides related to gingerdiol from ginger and their antioxidative activities. Journal of Agricultural and Food Chemistry., 48: 373-377.
[20]	Zancan KC, Marques MO, Petenate A, Meireless MA (2002). Extraction of ginger (Z. O Roscoe) oleoresin with CO2 and co-solvent: a study of the antioxidant action of the extracts. J. Supercrit. Flu., 24: 57-76.
[21]	Fathiazad, F.; Khaki, A. and Ahmadnejad, B. (2012). Protective Effect of Ginger on Gentamicin-Induced Apoptosis in Testis of Rats Afshin Zahedi. Advanced Pharmaceutical Bulletin., 2(2): 197-200.
[22]	Fisher–Rasmussen, W.; Kjaer, S.; Dahl, C. and Asping, U. (1991). Ginger treatment of Hyperemesis gravidarm. European Journal of Obstetrics & Gynecology and Reproductive Biology., 38 19-24.
[23]	Sharma, J.; Srivastava, K. and Gan, E. (1994). Suppressive effects of eugenol and ginger oil on arthritic rats. Pharmacology., 49 314-8.
[24]	Kamtchouing, P.; Mbongue Fandio, G. Y.; Dimo, T. and Jatsa, H.B. (2002). Evaluation of angrogenic activity of Zingiberofficinale and pentadiplandrabrazzeana in male rats. Asian Journal of Andrology., 4 299-301.
[25]	Khan, M. S.; Safdar, M.; Khan, M. M.; Khattak, K. N. and Anderson, R.A. (2003). Cinnamon improves glucose and lipids of people with type 2 diabetes. Diabetes Care., 26: 3215-3218.
[26]	Shobana, S. and Naidu, K. A. (2000). Antioxidant activity of selected Indian spices. Prostaglandins Leukot Essent Fatty Acids., 62: 107-110.
[27]	Shalaby, M. A. and Samar, M. M. (2010). Effect of Zingiber officinale Roots and Cinnamon zeylanicum Bark on Fertility of Male Diabetic Rats. Global Veterinaria., 5 (6): 341-347.
[28]	AOAC, (2000). Association of Official Analytical Chemists. Official Methods 965.33. Official Methods of Analysis, 17 Ed., Gaithersburg, MD.
[29]	Pellet, P. I. and S. Sossy, (1970). Food Composition Tables for use in the Middle East. American University of Beirut, Beirut- Lebanon.
[30]	Reeves, P. G.; Nielsen, F. H. and Fahey, G. C. (1993). AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. J Nutr., 123: 1939-51.
[31]	Wilke, T. J. and Utley, D. J. (1987). Total testosterone, free androgenic index and calculated free testosterone by analog RIA method. Clinical Chemistry, 33: 1372-1375.
[32]	Loraine, J. A. and Bell, E. T. (1976). Hormone Assays and their Clinical Application. The 2 Edition, Churchill Livingstone. New York, pp: 221.
[33]	Miller, C.; Rice-Evans, M. J.; Davis, V.; Gopinathan, Q. A. and Milner, A. (1993). A novel method for measuring antioxidant capacity and its application to monitoring antioxidant status in premature neonates. Clin. Sci., 84: 407-412.
[34]	Draper, H. H. and Hadley, M. (1990). Malondialdehyde determination as index of lipid peroxidation. Methods Enzymol., 186: 421-431.
[35]	Bergmeyer, H. U.; Schreiber, P. and Wahlefeld, A. W. (1978). Optimization of methods for aspartate and alanine aminotransferase. Clinical Chemistry., 24: 58-61.
[36]	Belfield, A. and Goldberg. D. M. (1971). Revised assay for serum phenyl phosphatase activity using 4- amino-antipyrine-enzyme.; 12: 561-573.
[37]	SPSS, (1986).Statistical package for social science, version 19. SPSS Inc., II. U. S. A.
[38]	Modaresi, M.; Mesripour, M.; AsadiMargh Maleki, M. and Hamedanian, M. K. (2008).The effect of saffron extract on testis tissue. Iranian journal of medicinal and aromatic plants., 24: 237-243.
[39]	Yiming, L.; Tran V.; Duke C. and Roufogalis B. (2012). Preventive and Protective Properties of Zingiber officinale (Ginger) in Diabetes Mellitus, Diabetic Complications, and Associated Lipid and Other Metabolic Disorders: A Brief Review. Evid Based Complement Alternat Med., 516870.
[40]	Dashak, D. A. and Fali, C. N., (1993). Chemical composition of four varieties of Nigerian bennised (Sesamum indicum). Food Chem., 47: 253-255.
[41]	El Khier, M.; Ishag K. E. A. and Yagoub, A. A. (2008). Chemical composition and oil characteristics of sesame seed cultivars grown in Sudan. Research J. Agriculture and Biological Sci., 4(6): 761-766.
[42]	Nzikou, J. M.; Matos, L.; Bouanga-Kalou, G. and et al., (2009). Chemical Composition on the Seeds and Oil of Sesame (Sesamum indicum L.) Grown in Congo-Brazzaville. Advance Journal of Food Science and Technology., 1(1): 6-11.
[43]	Mohammed, N.; Alyemeni, A.; Basahy, Y. and Sher, H. (2011). Physico-chemical analysis and mineral composition of some sesame seeds (Sesamum indicum L.) grown in the Gizan area of Saudi Arabia. Journal of Medicinal Plants Research., 5(2): 270-274.
[44]	Shyu, Y. S. and Hwang, L. S. (2002). Antioxidative activity of the crude extract of lignan glycosides from unroasted Burma black sesame meal. Food Research International., 35: 357-365.
[45]	Martinchik, A. N. (2011). Nutritional value of sesame seeds., Vopr Pitan., 80(3): 41-3.
[46]	Shittu, L.; Shittu, R. K.; Adesite, S. O.; Ajala, M. O.; Bankole, M. A.; Benebo, A. S.; et al. (2008). Sesame radiatum Phytoestrogens Stimulate Spermatogenic Activity and Improve Sperm Quality in Adult Male Sprague Dawley Rat Testis. Int. J. Morphol., 26(3): 643-52.
[47]	Alyemeni, M.; Basahy, A. and Sher, H. (2011). Physico-chemical analysis and mineral composition of some sesame seeds (Sesamum indicum L.) grown in the Gizan area of Saudi Arabia .Journal of Medicinal Plants Research., 5(2): 270-274.
[48]	Amini, J.; Hassani H.; Nikzad, H.; Taherian, A. and Salehi, M. (2013). Effect of Diet Contains Sesame Seed on Adult Wistar Rat Testis., Int. J. Morphol., 31(1): 197-202.
[49]	Suleiman, S. A.; Ali, M. E.; Zaki, Z. M.; El-Malik, E. M. and Nasr, M. A. (1996). Lipid peroxidation and human sperm motility: protective role of Vitamin E. J Androl., 17: 530-537.
[50]	Eskenazi, B.; Kidd, S. A.; Marks, A. R.; Sloter, E.; Block, G. and Wyrobek, A. J. (2005). Antioxidant intake is associated with semen quality in healthy men. Hum Reprod., 20(4): 1006-1012.
[51]	Rengaraj, D. and Hong, Y. (2015). Effects of Dietary Vitamin E on Fertility Functions in Poultry Species., Int. J. Mol. Sci., 16: 9910-9921.
[52]	Grzanna, R.; Lindmark, L. and Frondoza, C. G. (2005). Ginger An Herbal Medicinal Product with Broad Anti-Inflammatory Actions. Journal of Medicinal Food., 8(2): 125-132.
[53]	Khaki, A.; Fathiazad, F.; Nouri, M.; Khaki, A. A.; Chelar, C. O.; Ghafari-Novin, M. and Hamadeh, M. (2009). The Effects of Ginger on Spermatogenesis and Sperm parameters of Rat. Iranian Journal of Reproductive Medicine., 7(1): 7-12.
[54]	Rajeev, K.; Gagan, G. and Narmada, P. (2006). Drug Therapy for Idiopathic Male Infertility: Rationale Versus Evidence. Journal of Urology., 176: 1307-1312.
[55]	Yang, H. S.; Han, D. K.; Kim, J. R. and Sim, J. C. (2006). Effects of alpha-tocopherol on cadmium-induced toxicity in rat testis and spermatogenesis. Journal of Korean Medical Science., 21: 445-451.
[56]	Mares, W. and Najam, W. (2012). The effect of Ginger on semen parameters and serum FSH, LH & testosterone of infertile men. Tikrit Medical Journal., 18(2): 322-329.
[57]	Memudu, A.; Akinrinade, I. D.; Ogundele, O. M., and Duru, F. (2012). Effects of long and short term treatment of aqueous extract of ginger (Zingibier Officinale) on male reproductive function of adult Sprague dawley rats. Journal of Medicine and Medical Science., 3(11): 692-696.
[58]	Raji, Y.; Udoh, U. S.; Mewoyaka, O. O.; Ononye, F. C. and Bolarinwa, A. F. (2003). Implication of reproductive endocrine malfunction in male antifertility efficacy of Azadirachta indica extract in rats. Afri. J. Med. Med. Sci., 32: 159-165.
[59]	Hemayatkhah, J.; Farzam.; Dehghani K. and Momeni, H. (2012). Effect of cinnamon extract on male reproductive physiology in mice. Advances in Environmental Biology., 6(10): 2731-2734.
[60]	Riaz, F.; Khan, U. A.; Ayub, M. and Shaukat, S. (2011). Protective role of ginger on lead induced derangement in plasma testosterone and luteinizing hormone levels of male Sprague Dawley rats. J Ayub Med Coll Abbottabad., 23(4): 24-7.
[61]	Onwuka, F. C.; Erhabor, O.; Eteng, M. U. and Umoh, I. B. (2011). Protective effects of ginger toward cadmium-induced testes and kidney lipid peroxidation and hematological impairment in albino rats. J Med Food., 14(7-8): 817-21.
[62]	Mashhadi, N. S.; Ghiasvand, R.; Hariri, M.; Askari, G.; Feizi, A.; Darvishi, L.; Hajishafiee, M. and Barani, A. (2013). Effect of ginger and cinnamon intake on oxidative stress and exercise performance and body composition in Iranian female athletes. Int J Prev Med., 4 (Suppl 1): S31-5.
[63]	Khaki, A.; Khaki, A.; Hajhosseini, L.; Golzar, F. and Ainehchi, N. (2014). The Anti-Oxidant Effects of Ginger and Cinnamon on Spermatogenesis Dys-function of Diabetes Rats., Afr J Tradit Complement Altern Med.; 11(4): 1-8.
[64]	Arikawe, A. P.; Oyerinde, A.; Olatunji-Bello, I. I. and Obika, L. F. (2012). Streptozotocin diabetes and insulin resistance impairment of spermatogenesis in adult rat testis: central vs. local mechanism. Niger J Physiol Sci., 27(2): 171-9.
[65]	Zhang, X.; Yamamoto, N.; Soramoto, S. and Takenaka I. (2001). Cisplatin-induced germ cell apoptosis in mouse testes. Arch Androl. 46: 43-49.
[66]	Sikka, S. C.; Rajasekaran, M. and Hellstrom, W. (1995). Role of oxidative stress and antioxidants in male infertility. J Androl.16: 464-8.
[67]	Sharma, R. K. and Agarwal, A. (1996). Role of reactive oxygen species in male infertility. Urology. 48: 835-50.
[68]	Shahidi, F.; Janitha, P. K. and Wanasundara, P. D. (1992). Critical Reviews in Food Science and Nutrition; 32: 67-103.
[69]	Jayalekshmy, A.; Arumugham, C. and Suja, K. P. (2001). Process for extraction of antioxidants from sesame seed/cake. US Patent. Appl., 60/04.004.
[70]	Shittu, L. (2006). The effect of the aqueous crude leaves extract of Sesamum radiatum compared to Mesterolone (proviron) on the adult male Sprague Dawley rats testis and epididymis., MSc Dissertation. Lagos State University, College of Medicine, Ikeja, Nigeria.
[71]	Abbasi, Z.; Tabatabaei, S.; Mazaheri, Y.; Barati, F. and Morovvati, H. (2013). Effects of Sesame Oil on the Reproductive Parameters of Diabetes Mellitus-Induced Male Rats., World J Mens Health.,31(2): 141-149.
[72]	Fathiazad, F.; Khaki, A.; Nouri, M. and Khaki, A. A. (2013). Effect of Cinnamon zeylanicum on serum Testosterone and anti-oxidants levels in Rats. IJWHRS 1: 29-35.
[73]	Moselhy, W. A.; Helmy, N. A.; Abdel-Halim, B. R.; Nabil, T. M., and Abdel-Hamid, M. I. (2012). Role of ginger against the reproductive toxicity of aluminium chloride in albino male rats. Reprod Domest Anim. 47(2): 335-43.
[74]	Adel, S. and Prakash, J. (2010). Chemical composition and antioxidant properties of ginger root (Zingiber officinale)., Journal of Medicinal Plants Research, 4(24): 2674-2679.
[75]	Stoilova, I.; Krastanov, A.; Stoyanova, A.; Denev, P. and Gargova, S. (2007). Antioxidant activity of a ginger extract (Zingiber officinale). Food Chemistry., 102: 764-770.
[76]	Hesham, N.; Moemen, L. A. and Abu Elela, M. H. (2008). Studying the levels of malondialdehyde and antioxidant parameters in normal and abnormal human seminal plasma. Aust J Basic Appl Sci., 2: 773-778.
[77]	Ikeda S.; Toyoshima K. and Yamashita K. (2001). Dietary Sesame Seeds Elevate a- and g-Tocotrienol Concentrations in Skin and Adipose Tissue of Rats Fed the Tocotrienol-Rich Fraction Extracted from Palm Oil., J. Nutr. 131: 2892-2897.
[78]	Yamashita K; Ikeda S. and Obayashi M. (2003). Comparative effects of flaxseed and sesame seed on Vitamin E and cholesterol levels in rats., Lipids., 38(12): 1249-55.
[79]	Jedlinska, M.; Bomba, G.; Jakubowski, K; Rotkiewicz, T.; Jana, B. and Penkowski, A. (2006). Impact of oxidative stress and supplementation with Vitamins E and C on testes morphology in rats. J. Reproduc., 52: 203-209.
[80]	Morakinyo, O. A.; Achema, P. and Adegoke, O. (2010). Effect of Zingiber Officinale (Ginger) on Sodium Arseniteae Induced Reproductive Toxicity in Male Rats. African Journal of Biomedical Research. 13(1): 39-45.
[81]	Kessopoulou, E.; Powers, H. J.; Sharma, K. K.; Pearson, M. J.; Russel, J. M. Cooke, I. D. and Barratt, C. L. (1995). A double-blind randomized placebo cross-over controlled trial using the antioxidant Vitamin E to treat reactive oxygen species associated male infertility. Fertil Steril. 64(4): 825-831.
[82]	Bolle, P.; Evandri, M. G. and Saso, L. (2002) The controversial efficacy of Vitamin E for human male infertility. Contraception. 65: 313-315.
[83]	Jayaprakasha, G. K.; Negi, P. S.; Jena, B. S. and Jagan, L. (2007). Antioxidant and antimutagenic activities of Cinnamomum zeylanicum fruit extracts. Journal of Food Composition and Analysis; 20: 330-336.
[84]	Roussel, A.; Hininger, F.; Benaraba, R.; Ziegenfuss, T. and Anderson, R. (2009). Antioxidant Effects of a Cinnamon Extract in People with Impaired Fasting Glucose That Are Overweight or Obese., Journal of the American College of Nutrition., 28(1): 16-21.
[85]	Taha, N.; Mandour A.; Mohamed M. and Emarha R. (2014). Effect of Sesame Oil on Serum and Liver Lipid Profile in Hyperlipidemic Rats. Alexandria Journal of Veterinary Sciences, 42: 17-25.
[86]	Rao, P. and Gan, S. (2014). Cinnamon: A Multifaceted Medicinal Plant. Evidence-Based Complementary and Alternative Medicine., 1-12.
[87]	Haniadka, R.; Saxena, A.; Shivashankara, A.; Fayad, R. and et al., (2013). Ginger Protects the Liver against the Toxic Effects of Xenobiotic Compounds: Preclinical Observations., Haniadka et al., J Nutr Food Sci, 3(5): 1-6.

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Naeem M. Rabeh. (2016). Effect of Halawa Tahinia Alone or with Ginger and Cinnamon on Sex Hormones in Adult Male Rats. International Journal of Nutrition and Food Sciences, 5(3), 211-219. https://doi.org/10.11648/j.ijnfs.20160503.19

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Naeem M. Rabeh. Effect of Halawa Tahinia Alone or with Ginger and Cinnamon on Sex Hormones in Adult Male Rats. Int. J. Nutr. Food Sci. 2016, 5(3), 211-219. doi: 10.11648/j.ijnfs.20160503.19

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Naeem M. Rabeh. Effect of Halawa Tahinia Alone or with Ginger and Cinnamon on Sex Hormones in Adult Male Rats. Int J Nutr Food Sci. 2016;5(3):211-219. doi: 10.11648/j.ijnfs.20160503.19

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@article{10.11648/j.ijnfs.20160503.19,
  author = {Naeem M. Rabeh},
  title = {Effect of Halawa Tahinia Alone or with Ginger and Cinnamon on Sex Hormones in Adult Male Rats},
  journal = {International Journal of Nutrition and Food Sciences},
  volume = {5},
  number = {3},
  pages = {211-219},
  doi = {10.11648/j.ijnfs.20160503.19},
  url = {https://doi.org/10.11648/j.ijnfs.20160503.19},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijnfs.20160503.19},
  abstract = {This study was performed to investigate the effect of halawa tahinia alone or in combination with ginger and cinnamon on sex hormones as well as serum antioxidant levels. Thirty Wistar adult male rat were divided into five groups, control group fed on basal diet only and test groups (n=24) divided into 4 groups as follow, group (1) fed on basal diet supplemented with halawa tahinia at the level of (15%), while the other three groups were fed on basal diet supplemented with halawa tahinia (15%) and were given orally (500 mg/kg/day) dried ginger, (500 mg/kg/day) dried cinnamon, both dried ginger and cinnamon (500 mg/kg/day) respectively for 8 weeks. The results indicated that, halawa tahinia have a high nutritive value. The obtained results revealed also that, oral administration of ginger and/ or cinnamon with halawa tahinia caused a significant (p<0.05) protective effects on testes due to increasing the levels of serum total testosterones, follicular stimulating hormone (FSH) and luteinizing hormone (LH) also increasing serum total antioxidants capacity (TAC) levels with decreasing malondialdehyde (MDA) level as well as have no deleterious effects on liver functions as compared to control group. Moreover, both ginger and cinnamon administration has a synergistic effect on infertility due to their antioxidant properties. In conclusion: These results provide scientific evidence to substantiate the traditional use of cinnamon and ginger as a drink as well as Halawa tahinia in improving infertility in male rats which might be a product for their potent antioxidant properties and androgenic activities.},
 year = {2016}
}

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TY  - JOUR
T1  - Effect of Halawa Tahinia Alone or with Ginger and Cinnamon on Sex Hormones in Adult Male Rats
AU  - Naeem M. Rabeh
Y1  - 2016/05/10
PY  - 2016
N1  - https://doi.org/10.11648/j.ijnfs.20160503.19
DO  - 10.11648/j.ijnfs.20160503.19
T2  - International Journal of Nutrition and Food Sciences
JF  - International Journal of Nutrition and Food Sciences
JO  - International Journal of Nutrition and Food Sciences
SP  - 211
EP  - 219
PB  - Science Publishing Group
SN  - 2327-2716
UR  - https://doi.org/10.11648/j.ijnfs.20160503.19
AB  - This study was performed to investigate the effect of halawa tahinia alone or in combination with ginger and cinnamon on sex hormones as well as serum antioxidant levels. Thirty Wistar adult male rat were divided into five groups, control group fed on basal diet only and test groups (n=24) divided into 4 groups as follow, group (1) fed on basal diet supplemented with halawa tahinia at the level of (15%), while the other three groups were fed on basal diet supplemented with halawa tahinia (15%) and were given orally (500 mg/kg/day) dried ginger, (500 mg/kg/day) dried cinnamon, both dried ginger and cinnamon (500 mg/kg/day) respectively for 8 weeks. The results indicated that, halawa tahinia have a high nutritive value. The obtained results revealed also that, oral administration of ginger and/ or cinnamon with halawa tahinia caused a significant (p<0.05) protective effects on testes due to increasing the levels of serum total testosterones, follicular stimulating hormone (FSH) and luteinizing hormone (LH) also increasing serum total antioxidants capacity (TAC) levels with decreasing malondialdehyde (MDA) level as well as have no deleterious effects on liver functions as compared to control group. Moreover, both ginger and cinnamon administration has a synergistic effect on infertility due to their antioxidant properties. In conclusion: These results provide scientific evidence to substantiate the traditional use of cinnamon and ginger as a drink as well as Halawa tahinia in improving infertility in male rats which might be a product for their potent antioxidant properties and androgenic activities.
VL  - 5
IS  - 3
ER  -

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Naeem M. Rabeh

Nutrition and Food Science Dept., Faculty of Home Economics, Helwan University, Cairo, Egypt

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Naeem M. Rabeh. (2016). Effect of Halawa Tahinia Alone or with Ginger and Cinnamon on Sex Hormones in Adult Male Rats. International Journal of Nutrition and Food Sciences, 5(3), 211-219. https://doi.org/10.11648/j.ijnfs.20160503.19

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Naeem M. Rabeh. Effect of Halawa Tahinia Alone or with Ginger and Cinnamon on Sex Hormones in Adult Male Rats. Int. J. Nutr. Food Sci. 2016, 5(3), 211-219. doi: 10.11648/j.ijnfs.20160503.19

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AMA Style

Naeem M. Rabeh. Effect of Halawa Tahinia Alone or with Ginger and Cinnamon on Sex Hormones in Adult Male Rats. Int J Nutr Food Sci. 2016;5(3):211-219. doi: 10.11648/j.ijnfs.20160503.19

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@article{10.11648/j.ijnfs.20160503.19,
  author = {Naeem M. Rabeh},
  title = {Effect of Halawa Tahinia Alone or with Ginger and Cinnamon on Sex Hormones in Adult Male Rats},
  journal = {International Journal of Nutrition and Food Sciences},
  volume = {5},
  number = {3},
  pages = {211-219},
  doi = {10.11648/j.ijnfs.20160503.19},
  url = {https://doi.org/10.11648/j.ijnfs.20160503.19},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijnfs.20160503.19},
  abstract = {This study was performed to investigate the effect of halawa tahinia alone or in combination with ginger and cinnamon on sex hormones as well as serum antioxidant levels. Thirty Wistar adult male rat were divided into five groups, control group fed on basal diet only and test groups (n=24) divided into 4 groups as follow, group (1) fed on basal diet supplemented with halawa tahinia at the level of (15%), while the other three groups were fed on basal diet supplemented with halawa tahinia (15%) and were given orally (500 mg/kg/day) dried ginger, (500 mg/kg/day) dried cinnamon, both dried ginger and cinnamon (500 mg/kg/day) respectively for 8 weeks. The results indicated that, halawa tahinia have a high nutritive value. The obtained results revealed also that, oral administration of ginger and/ or cinnamon with halawa tahinia caused a significant (p<0.05) protective effects on testes due to increasing the levels of serum total testosterones, follicular stimulating hormone (FSH) and luteinizing hormone (LH) also increasing serum total antioxidants capacity (TAC) levels with decreasing malondialdehyde (MDA) level as well as have no deleterious effects on liver functions as compared to control group. Moreover, both ginger and cinnamon administration has a synergistic effect on infertility due to their antioxidant properties. In conclusion: These results provide scientific evidence to substantiate the traditional use of cinnamon and ginger as a drink as well as Halawa tahinia in improving infertility in male rats which might be a product for their potent antioxidant properties and androgenic activities.},
 year = {2016}
}

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TY  - JOUR
T1  - Effect of Halawa Tahinia Alone or with Ginger and Cinnamon on Sex Hormones in Adult Male Rats
AU  - Naeem M. Rabeh
Y1  - 2016/05/10
PY  - 2016
N1  - https://doi.org/10.11648/j.ijnfs.20160503.19
DO  - 10.11648/j.ijnfs.20160503.19
T2  - International Journal of Nutrition and Food Sciences
JF  - International Journal of Nutrition and Food Sciences
JO  - International Journal of Nutrition and Food Sciences
SP  - 211
EP  - 219
PB  - Science Publishing Group
SN  - 2327-2716
UR  - https://doi.org/10.11648/j.ijnfs.20160503.19
AB  - This study was performed to investigate the effect of halawa tahinia alone or in combination with ginger and cinnamon on sex hormones as well as serum antioxidant levels. Thirty Wistar adult male rat were divided into five groups, control group fed on basal diet only and test groups (n=24) divided into 4 groups as follow, group (1) fed on basal diet supplemented with halawa tahinia at the level of (15%), while the other three groups were fed on basal diet supplemented with halawa tahinia (15%) and were given orally (500 mg/kg/day) dried ginger, (500 mg/kg/day) dried cinnamon, both dried ginger and cinnamon (500 mg/kg/day) respectively for 8 weeks. The results indicated that, halawa tahinia have a high nutritive value. The obtained results revealed also that, oral administration of ginger and/ or cinnamon with halawa tahinia caused a significant (p<0.05) protective effects on testes due to increasing the levels of serum total testosterones, follicular stimulating hormone (FSH) and luteinizing hormone (LH) also increasing serum total antioxidants capacity (TAC) levels with decreasing malondialdehyde (MDA) level as well as have no deleterious effects on liver functions as compared to control group. Moreover, both ginger and cinnamon administration has a synergistic effect on infertility due to their antioxidant properties. In conclusion: These results provide scientific evidence to substantiate the traditional use of cinnamon and ginger as a drink as well as Halawa tahinia in improving infertility in male rats which might be a product for their potent antioxidant properties and androgenic activities.
VL  - 5
IS  - 3
ER  -

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