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Melatonin “Pearls” in Psychiatry

Received: 16 July 2016     Accepted: 16 August 2016     Published: 7 September 2016
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Abstract

Melatonin use in clinical psychiatry currently is rife. Efficacy coupled with safety and lack of abuse potential render melatonin an attractive therapeutic option. Data accrues speaking to the idea of a pluripotent molecule beyond a sleep-aid. Here, authors would shed some light on melatonin use in psychiatry.

Published in International Journal of Psychological and Brain Sciences (Volume 1, Issue 2)
DOI 10.11648/j.ijpbs.20160102.12
Page(s) 29-31
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2016. Published by Science Publishing Group

Keywords

Melatonin, ASD, ADHD, Bipolar, Schizophrenia, AD, TD, Metabolic Syndrome

References
[1] Sanchez-Barcelo EJ, Mediavilla MD, Reiter RJ. Clinical Uses of Melatonin in Pediatrics. Int J Pediatr. 2011; 2011: 892624.
[2] Wright B, Sims D, Smart S, et al. Melatonin versus placebo in children with autism spectrum conditions and severe sleep problems not amenable to behaviour management strategies: a randomised controlled crossover trial. J Autism Dev Disord. 2011; 41 (2): 175-84.
[3] Malow BA, Adkins KW, Mc Grew SG, et al. Melatonin for Sleep in Children with Autism: A Controlled Trial Examining Dose, Tolerability, and Outcomes. J Autism Dev Disord. 2012; 42 (8): 1729-1737
[4] Van der Heijden KB, Smits MG, Van Someren EJ, et al. Effect of melatonin on sleep, behaviour, and cognition in ADHD and chronic sleep-onset insomnia. J Am Acad Child Adolesc Psychiatry. 2007; 46 (2): 233-41.
[5] Niederhofer H, Staffen W, Mair A, et al. Brief report: melatonin facilitates sleep in individuals with mental retardation and insomnia. J Autism Dev Disord. 2003; 33 (4): 469-72.
[6] Jain S, Besag FM. Does Melatonin affect epileptic seizures? Drug Saf. 2013; 36 (4): 207-15.
[7] Naguy A, Francis K. Melatonin: A New Game-Changer in Juvenile Bipolar Disorders? Psychiatr Res. 2016 (in Press).
[8] Bersani, G., Garavini, A. Melatonin add-on in manic patients with treatment resistent insomnia. Prog Neuropsychopharmacol Biol Psychiatry. 2000; 24 (2): 185-91.
[9] Robertson JM, Tanguay PE. Case Study: The Use of Melatonin in a Boy With Refractory Bipolar Disorder. J Am Acad Child Adolesc Psychiatry. 1997; 36 (6): 822-825.
[10] Anderson, G., Maes, M. Melatonin: an overlooked factor in schizophrenia and in the inhibition of anti-psychotic side effects. Metab Brain Dis. 2012; 27 (2): 113-119.
[11] Morera-Fumero AL, Abreu-Gonzalez P. Role of Melatonin in Schizophrenia. Int J Mol Sci. 2013; 14 (5): 9037-9050.
[12] Cardinali DP, Furio AM, Brusco LI. Clinical Aspects of Melatonin Intervention in Alzheimer’s Disease Progression. Curr Neuropharmacol 2010; 8 (3): 218-227.
[13] Chen S, Shi L, Liang F, et al. Exogenous Melatonin for Delirium Prevention: a Meta-analysis of Randomized Controlled Trials. Mol Neurobiol. 2016; 53 (6): 4046-53.
[14] Shamir E, Barak Y, Shalman I, et al. Melatonin treatment for tardive dyskinesia: a double-blind, placebo-controlled, crossover study. Arch Gen Psychiatry. 2001; 58 (11): 1049-52.
[15] Romo-Nava, F., Gonzalez, D., Fresan-Orellana, A., et al. Melatonin attenuates antipsychotic metabolic effects: an eight-week randomized, double-blind, parallel-group, placebo-controlled clinical trial. Bipolar Disord. 2014; 16 (4): 410-421.
[16] Goyal, A., Terry, P. D., Superak, H. M et al. Melatonin supplementation to treat the metabolic syndrome: a randomized controlled trial. Diabetol Met Synd. 2014; 6: 124.
Cite This Article
  • APA Style

    Ahmed Naguy, Pavly Samir. (2016). Melatonin “Pearls” in Psychiatry. International Journal of Psychological and Brain Sciences, 1(2), 29-31. https://doi.org/10.11648/j.ijpbs.20160102.12

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    ACS Style

    Ahmed Naguy; Pavly Samir. Melatonin “Pearls” in Psychiatry. Int. J. Psychol. Brain Sci. 2016, 1(2), 29-31. doi: 10.11648/j.ijpbs.20160102.12

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    AMA Style

    Ahmed Naguy, Pavly Samir. Melatonin “Pearls” in Psychiatry. Int J Psychol Brain Sci. 2016;1(2):29-31. doi: 10.11648/j.ijpbs.20160102.12

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  • @article{10.11648/j.ijpbs.20160102.12,
      author = {Ahmed Naguy and Pavly Samir},
      title = {Melatonin “Pearls” in Psychiatry},
      journal = {International Journal of Psychological and Brain Sciences},
      volume = {1},
      number = {2},
      pages = {29-31},
      doi = {10.11648/j.ijpbs.20160102.12},
      url = {https://doi.org/10.11648/j.ijpbs.20160102.12},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijpbs.20160102.12},
      abstract = {Melatonin use in clinical psychiatry currently is rife. Efficacy coupled with safety and lack of abuse potential render melatonin an attractive therapeutic option. Data accrues speaking to the idea of a pluripotent molecule beyond a sleep-aid. Here, authors would shed some light on melatonin use in psychiatry.},
     year = {2016}
    }
    

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Author Information
  • Al-Manara CAP Centre, Kuwait Centre for Mental Health (KCMH), Jamal Abdul-Nassir St, Shuwaikh, State of Kuwait

  • Ibrahim Bin Hamad Obaidullah Hospital, Ras Al-Khaimah, United Arab of Emirates

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