Abstract: This work performs the metrological comparison of two groups of indicators estimating the average level of EEG–potentials. The indirect spectral indicators (ISI) based on amplitude spectrum and power spectrum are contrasted with natural indicators (NI) based on period-amplitude analysis, on EEG absolute value and on EEG envelope. Five major results were obtained: 1) NI give almost equivalent estimates that differ from ISI significantly; 2) NI demonstrate smooth dynamics of their value change at successive epochs whereas ISI are subject to drastic and casual fluctuations; 3) ISI unlike NI do not possess the additivity property of statistical averaging, their estimates depending on number and length of averaged epochs can differ over 3 times in their values; 4) ISI at simulated signals with a known amplitude ratio give estimates that differ 1.4–1.55 times from true value whereas NI show the proper estimates; 5) ISI depending on differences between EEG spectral distribution give estimates which differ over 5 times in their ratios while NI show the same ratios which differ 1.38–3.7 times from ISI. The least reliable results in all comparisons are related to the power spectrum. These conclusions do not allow to qualify metrologically ISI as an analytical tool that is adequate for the nature and peculiarities of EEG potentials. Their use may lead to incompatibility of the results obtained by different researchers and clinicians.Abstract: This work performs the metrological comparison of two groups of indicators estimating the average level of EEG–potentials. The indirect spectral indicators (ISI) based on amplitude spectrum and power spectrum are contrasted with natural indicators (NI) based on period-amplitude analysis, on EEG absolute value and on EEG envelope. Five major results...Show More
Abstract: Melatonin use in clinical psychiatry currently is rife. Efficacy coupled with safety and lack of abuse potential render melatonin an attractive therapeutic option. Data accrues speaking to the idea of a pluripotent molecule beyond a sleep-aid. Here, authors would shed some light on melatonin use in psychiatry.
Hayder Mutter Al-Kuraishy,Maryam Mohammed Hammed,Haider W. Alsarhan
Issue:
Volume 1, Issue 2, October 2016
Pages:
32-39
Received:
6 September 2016
Accepted:
21 September 2016
Published:
11 October 2016
DOI:
10.11648/j.ijpbs.20160102.13
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Abstract: Hearing loss is the most common sensory disability in the world, hearing loss should be early diagnosed and treated since; it leads to speech and language disorders. Auditory brainstem response (ABR) or Auditory evoked potential (AEP) is a neurologic test done by an audiologist to measure auditory evoke potential. Different types of sedation levels are used during auditory brainstem response test. Therefore, the aim of present study was evaluation of the sedative effect of chloral hydrate during auditory brainstem response (ABR) on children with hearing problems. Randomized selection of 160 children with age ranged between 1-5 years with hearing disorders, they were divided into: Group A: Received 20 mg/Kg chloral hydrate orally. Group B: Received 20 mg/Kg chloral hydrate orally plus 0.5 mg/Kg diazepam rectally. Group C: Received 40 mg/Kg chloral hydrate orally. Group D: Received 40 mg/Kg chloral hydrate orally plus 0.5 mg/Kg diazepam rectally. Regarding ABR testing results, positive ABR test was superior in combined group compared to other groups p=0.005 whereas; negative ABR test was low in combined group compared to other groups p=0.006. At the end of ABR testing 118.52±9.88 of testing children in combined group completed the test compared to other groups p=0.0139 while; 98.21±7.22 of testing children in combined group not completed ABR test compared to other groups p=0.005.In conclusion, combined chloral hydrate plus diazepam give more significant sedative effect than chloral hydrate alone during ABR testing in children with hearing disorders.Abstract: Hearing loss is the most common sensory disability in the world, hearing loss should be early diagnosed and treated since; it leads to speech and language disorders. Auditory brainstem response (ABR) or Auditory evoked potential (AEP) is a neurologic test done by an audiologist to measure auditory evoke potential. Different types of sedation levels...Show More
