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Increased Anti-mullerian Hormone (AMH) After Delivery: Case Report

Received: 15 June 2016     Accepted: 25 June 2016     Published: 15 July 2016
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Abstract

Anti-mullerian hormone (AMH) is mainly produced by antral follicles. AMH is widely used as a useful biomarker to reflect ovarian reserve and it was reported to reveal less changes during the course of pregnancy and early puerperium. A 29-year old woman visited our hospital for infertility treatment. Her serum level of AMH was 1.12ng/ml, which was lower for her age. She conceived by intra-uterine sperm insemination (IUI) treatment with clomiphen citrate. About 6 months after delivery, her serum level of AMH rose up to 3.34ng/ml, which was about the average level for her age. This result indicated that even if the serum AMH level is low initially, there is the possibility for higher levels of serum AMH at a later date.

Published in Journal of Gynecology and Obstetrics (Volume 4, Issue 3)
DOI 10.11648/j.jgo.20160403.12
Page(s) 17-18
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2016. Published by Science Publishing Group

Keywords

Anti-mullerian Hormone (AMH), Ovarian Reserve, Pregnancy, Delivery

References
[1] B. F. van Rooij IA, Scheffer GJ, Looman CW, Habbema JD, de Jong FH, Fauser BJ, Themmen AP, te Velde ER ''Serum antimullerian hormone levels best reflect the reproductive decline with age in normal women with proven fertility: a longitudinal study'' Fertil Steril, Vol 83, pp 979-987, Apr 2005.
[2] K. S. Al-Azemi M 1, Duffy S, Pye C, Refaat B, Hill N, Ledger W ''Multi-marker assessment of ovarian reserve predicts oocyte yield after ovulation induction.'' Hum Reprod Vol 26, pp 414-422, Feb 2011.
[3] H. G. Hansen KR 1, Knowlton N, Craig LB ''Correlation of ovarian reserve tests with histologically determined primordial follicle number.'' Fertil Steril, Vol 95, pp 170-175 Jan 2011.
[4] V. J. Lie Fong S, Welt CK, de Rijke YB, Eijkemans MJ, Broekmans FJ, Rose EM, Peters WH, Hokken-Koelega AC, Fauser BC, Themmen AP, de Jong FH, Schipper I, Laven JS ''Serum anti-müllerian hormone levels in healthy females: a nomogram ranging from Infancy to adulthood'' J Clin Endocrinol Metab Vo. 97, pp 4650-4655, Dec 2012.
[5] G. S. La Marca A, Orvieto R, De Leo V, Volpe A ''Anti-Müllerian hormone concentrations in maternal serum during pregnancy'' Hum Reprod, Vol 20, pp 1569-1572, Jan 2005.
[6] K. A. Köninger A 1, Schmidt B, Schmidt M, Yerlikaya, G, Kasimir-Bauer S, Kimmig R, Birdir C ''Anti-Mullerian-hormone levels during pregnancy and postpartum'', Reprod Biol Endocrinol, Jul 2013.
[7] F. P. Massé V 1, Boucoiran I, Delotte J, Isnard V, Bongain A ''Normal serum concentrations of anti-Mullerian hormone in a population of fertile women in their first trimester of pregnancy'' Hum Reprod, Vol 26, pp 3431-3436, Dec 2011.
[8] d. M. J. Streuli I 1, Paccolat C 3, Chapron C 4, Petignat P 3, Irion OP 3, de Ziegler D 2 '' AMH concentration is not related to effective time to pregnancy in women who conceive naturally'' Reprod Biomed Online, Feb 2014.
[9] E. S. DeFranco EA, Muglia LJ ''Influence of interpregnancy interval on birth timing'' BJOG Vol 121, pp 1633-1640, Dec 2014.
[10] H. W. Iwase A, Goto M, Takikawa S, Nagatomo Y, Nakahara T, Manabe S, Kikkawa F., ''Serum anti-Müllerian hormone level is a useful marker for evaluating the impact of laparoscopic cystectomy on ovarian reserve'' Fertil Steril, Vol 94, pp 2846-2849 Dec 2010.
Cite This Article
  • APA Style

    Keiichi Kumasawa, Yuri Yasui, Hitomi Nakamura, Tadashi Kimura. (2016). Increased Anti-mullerian Hormone (AMH) After Delivery: Case Report. Journal of Gynecology and Obstetrics, 4(3), 17-18. https://doi.org/10.11648/j.jgo.20160403.12

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    ACS Style

    Keiichi Kumasawa; Yuri Yasui; Hitomi Nakamura; Tadashi Kimura. Increased Anti-mullerian Hormone (AMH) After Delivery: Case Report. J. Gynecol. Obstet. 2016, 4(3), 17-18. doi: 10.11648/j.jgo.20160403.12

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    AMA Style

    Keiichi Kumasawa, Yuri Yasui, Hitomi Nakamura, Tadashi Kimura. Increased Anti-mullerian Hormone (AMH) After Delivery: Case Report. J Gynecol Obstet. 2016;4(3):17-18. doi: 10.11648/j.jgo.20160403.12

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  • @article{10.11648/j.jgo.20160403.12,
      author = {Keiichi Kumasawa and Yuri Yasui and Hitomi Nakamura and Tadashi Kimura},
      title = {Increased Anti-mullerian Hormone (AMH) After Delivery: Case Report},
      journal = {Journal of Gynecology and Obstetrics},
      volume = {4},
      number = {3},
      pages = {17-18},
      doi = {10.11648/j.jgo.20160403.12},
      url = {https://doi.org/10.11648/j.jgo.20160403.12},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jgo.20160403.12},
      abstract = {Anti-mullerian hormone (AMH) is mainly produced by antral follicles. AMH is widely used as a useful biomarker to reflect ovarian reserve and it was reported to reveal less changes during the course of pregnancy and early puerperium. A 29-year old woman visited our hospital for infertility treatment. Her serum level of AMH was 1.12ng/ml, which was lower for her age. She conceived by intra-uterine sperm insemination (IUI) treatment with clomiphen citrate. About 6 months after delivery, her serum level of AMH rose up to 3.34ng/ml, which was about the average level for her age. This result indicated that even if the serum AMH level is low initially, there is the possibility for higher levels of serum AMH at a later date.},
     year = {2016}
    }
    

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    AU  - Keiichi Kumasawa
    AU  - Yuri Yasui
    AU  - Hitomi Nakamura
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    T2  - Journal of Gynecology and Obstetrics
    JF  - Journal of Gynecology and Obstetrics
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    AB  - Anti-mullerian hormone (AMH) is mainly produced by antral follicles. AMH is widely used as a useful biomarker to reflect ovarian reserve and it was reported to reveal less changes during the course of pregnancy and early puerperium. A 29-year old woman visited our hospital for infertility treatment. Her serum level of AMH was 1.12ng/ml, which was lower for her age. She conceived by intra-uterine sperm insemination (IUI) treatment with clomiphen citrate. About 6 months after delivery, her serum level of AMH rose up to 3.34ng/ml, which was about the average level for her age. This result indicated that even if the serum AMH level is low initially, there is the possibility for higher levels of serum AMH at a later date.
    VL  - 4
    IS  - 3
    ER  - 

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Author Information
  • Division of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan

  • Division of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan

  • Division of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan

  • Division of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan

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