-
Research Article
Comorbidity Pattern and Autonomic Nervous System Dysfunction in Patients with Chronic Vulvar Discomfort
Vesna Harni*
,
Damir Babic,
Suzana Ljubojevic Hadzavdic,
Dubravko Barisic,
Magdalena Karadza
Issue:
Volume 12, Issue 6, December 2024
Pages:
118-131
Received:
20 September 2024
Accepted:
10 October 2024
Published:
12 November 2024
DOI:
10.11648/j.jgo.20241206.11
Downloads:
Views:
Abstract: This study examines novel concepts of comorbidity in patients with chronic vulvar discomfort using data from the DATRIV (Diagnostic Accuracy of Three Rings Vulvoscopy) study, which involved 328 participants categorized into four groups: asymptomatic individuals with normal or impaired vulvar skin and patients with chronic vulvar discomfort, classified as either vulvodynia or vulvar dermatosis. Clinical data were collected through a structured questionnaire and analyzed using statistical software, including StatSoft (Dell, Austin, TX, USA), Statistica 12 (TIBCO®, Palo Alto, CA, USA), and SPSS 20 (IBM, Armonk, NY, USA). The study received approval from the Institutional Review Board of Polyclinic Harni, and all participants provided written informed consent. The findings reveal significantly higher comorbidity rates in patients with chronic vulvar discomfort compared to other groups (p = 0.0000). A substantial percentage of asymptomatic participants with both normal (63.4%) and impaired (70.7%) vulvar skin also reported comorbid conditions. Analysis of comorbidity curves revealed distinct patterns of symptom progression, with a gradual increase in frequency from asymptomatic individuals to patients with vulvodynia, followed by a decline in vulvar dermatosis cases. These patterns highlight the central role of autonomic nervous system (ANS) dysfunction, where sympathetic hyperactivity and parasympathetic depression contribute to separate comorbidity chains. These dysfunctions may act independently or concurrently, leading to various health issues. The elevated comorbidity rates and overlapping symptomatology suggest complex pathophysiology driven by ANS dysregulation. Further research on comorbidity clusters may unveil new therapeutic targets and guide the development of multifaceted treatment strategies.
Abstract: This study examines novel concepts of comorbidity in patients with chronic vulvar discomfort using data from the DATRIV (Diagnostic Accuracy of Three Rings Vulvoscopy) study, which involved 328 participants categorized into four groups: asymptomatic individuals with normal or impaired vulvar skin and patients with chronic vulvar discomfort, classif...
Show More
-
Research Article
Study of Knowledge, Attitudes and Practices of Family Planning: Case of Female Staff of the Communal Medical Center (CMC) of Flamboyants, Conakry, Guinea
Sow Alhassane II*,
Diallo Ibrahima Tangaly,
Bah Ibrahima Koussy,
Keita Massa,
Balde Abdoul Aziz,
Diallo Boubacar Sidy,
Balde Abdoulaye Djibril,
Sylla Aboubacar M’mah,
Balde Boubacar Talibe,
Diallo Abdourahamane,
Balde Ibrahima Sory,
Sy Telly
Issue:
Volume 12, Issue 6, December 2024
Pages:
132-139
Received:
29 September 2024
Accepted:
18 October 2024
Published:
12 November 2024
DOI:
10.11648/j.jgo.20241206.12
Downloads:
Views:
Abstract: Introduction: The aim was to assess the knowledge, attitudes and practices of female staff on family planning at the Flamboyants Communal Medical Center. Methods: This was a 3-month cross-sectional, prospective, descriptive and analytical study involving women (doctors, midwives, laboratory technicians and nurses) working at the Flamboyants CMC and agreeing to participate in the study. Results: The contraceptive prevalence was 61.9%. All respondents were aware of FP (100%). The most commonly cited contraceptive methods were: the intrauterine device (IUD) at 85.7%, the Jadelle implant (79.4%) and the contraceptive pill (68.3%). More than 8 out of 10 respondents (81.0%) were in favor of using family planning. Most of the respondents, 74.5%, discussed family planning with their spouses and 70.2% of the spouses were in favor of FP. The most frequently used method was the pill (59.0%). The factors associated with the use of FP were: dialogue with the spouse on contraception (p = 0.018), marriage (p = 0.012) and good attitude of the spouse towards FP (p = 0.000). Conclusion: Improving this prevalence would require the involvement of spouses and midwives during counseling during antenatal and postpartum follow-up.
Abstract: Introduction: The aim was to assess the knowledge, attitudes and practices of female staff on family planning at the Flamboyants Communal Medical Center. Methods: This was a 3-month cross-sectional, prospective, descriptive and analytical study involving women (doctors, midwives, laboratory technicians and nurses) working at the Flamboyants CMC and...
Show More
-
Research Article
The Effects of Intra-Operative Lidocaine Infusion on Post Operative Pain and Morphine Consumption Following Major Gynaecological Surgeries Under General Anaesthesia
Issue:
Volume 12, Issue 6, December 2024
Pages:
140-149
Received:
1 October 2024
Accepted:
22 October 2024
Published:
12 November 2024
DOI:
10.11648/j.jgo.20241206.13
Downloads:
Views:
Abstract: Introduction: Major gynaecological surgeries are associated with considerable postoperative pain, which remains a challenge for many practitioners. Multimodal forms of analgesia significantly reduce the requirement of opioids for pain management. Despite its local anaesthetic effects, lidocaine infusion improves postoperative pain and morphine consumption following gynaecological surgeries. Materials and methods: Sixty patients were assigned randomly into 2 groups (A and B) with 30 patients per group. Group A received intravenous lidocaine 1.5 mg/kg at induction via a bolus injection and 1.5 mg/kg/hr in normal saline infusion from onset of surgery to the end of surgery, while the control group (Group B) received equal volume of normal saline at the same timelines. Pain scores were assessed postoperatively using the numerical rating scale and the cumulative morphine consumed postoperatively were also measured. Results: The mean pain scores were significantly higher in the Saline Group than in the Lidocaine group. The cumulative morphine consumption after 48 hours was significantly reduced in the study group 4.87 ± 1.80 mg vs 14.13 ± 4.10 mg (P<0.0001). Conclusion: The administration of a bolus dose (1.5 mg/kg) of intravenous lidocaine at induction and a continuous intravenous infusion of 1.5 mg/kg/hr from onset of surgery till skin closure reduced the postoperative pain intensity and morphine consumption in patients undergoing major gynaecological surgeries under general anaesthesia.
Abstract: Introduction: Major gynaecological surgeries are associated with considerable postoperative pain, which remains a challenge for many practitioners. Multimodal forms of analgesia significantly reduce the requirement of opioids for pain management. Despite its local anaesthetic effects, lidocaine infusion improves postoperative pain and morphine cons...
Show More
-
Research Article
Prelacteal Feeding and Associated Factors Among Mothers of Children Aged Less Than Six Months in Gozamen District, 2019: A Community Based Cross Sectional Study
Issue:
Volume 12, Issue 6, December 2024
Pages:
150-160
Received:
25 September 2024
Accepted:
29 October 2024
Published:
22 November 2024
Abstract: Background: Prelacteal feeding (PLF) is administration of any food or fluid other than breast milk before initiation of breast feeding. Optimal breastfeeding including discouraging prelacteal feeding could save 823,000 lives per year among children ages five years old and younger. Despite of this mothers give prelacteal feeding to their child in different part of Ethiopia. However, there is a paucity of information on prevalence of prelacteal feeding and associated factors in the study area. Thus, the current study aimed at determining of the prevalence of prelacteal feeding and associated factors among mothers of children aged less than six months in Gozamen district, East Gojjam zone, North West Ethiopia, 2020. Methods: A community based cross-sectional study was conducted among seven hundred forty-one (741) mothers of children aged less than six months in Gozamen district from August 1 to September 12 /2019. Stratified cluster sampling technique was used to select study participants. Data were collected by face to face interviewer-administered, pretested and semi-structured questionnaire. Descriptive analysis, bi-variable and multivariable logistic regression model were employed. Adjusted odds ratio with 95% confidence interval was used to identify factors associated with prelacteal feeding. Results: In this study the prevalence of prelacteal feeding was found to be 17.1%with 95%CI [14.3, 20]. Mothers who had no ANC follow up [AOR: 7.53, CI; 3.32, 17.05], those mothers who did not discard colostrum [AOR: 0.12, CI; 0.07, 0.12] time of breast feeding initiation [AOR: 3.53, CI; 2.05, 6.11] and mothers who had single ANC visit [AOR: 2.98, CI; 1.52, 5.85] were significant independent factors associated with prelacteal feeding. Conclusion: This study concluded that prelacteal feeding was high in the study area. Therefore, in order to tackle this problem strengthening antenatal follow up, timely initiation of breastfeeding, health education and awarenes creation of the communities are recommended interventions.
Abstract: Background: Prelacteal feeding (PLF) is administration of any food or fluid other than breast milk before initiation of breast feeding. Optimal breastfeeding including discouraging prelacteal feeding could save 823,000 lives per year among children ages five years old and younger. Despite of this mothers give prelacteal feeding to their child in di...
Show More
-
Case Report
Cyclopia Associated with Microcephaly, Hydrocephaly and Clubfoot: A Case Report from Burkina Faso, West Africa
Issue:
Volume 12, Issue 6, December 2024
Pages:
161-164
Received:
25 July 2024
Accepted:
21 August 2024
Published:
28 November 2024
Abstract: Cyclopia is the most severe form of alobar holoprosencephaly, characterized by the fusion of the two orbits into one. It is a genetic disease incompatible with life. It is most often associated with other craniofacial malformations such as microcephaly, cleft lip and palate, nasal agenesis and facial dysmorphia. The incidence of cyclopia varies from 1/13,000 to 1/20,000 births, and the etiology of this malformation has yet to be elucidated. These include genetic factors, multiparity, female gender, unexplained miscarriage, gestational diabetes, infections during pregnancy, UV radiation, smoking and alcohol consumption. It is probably less diagnosed in developing countries, where pregnancies are not normally monitored, and antenatal ultrasound is less common. We report the case of a 22-year-old pregnant woman, third gesture and two pares with two live children. She came on her own for a third-trimester ultrasound. She had a spontaneous pregnancy. She reported no previous history of a spontaneous pregnancy. Morphological ultrasound revealed cyclopia associated with microcephaly and hydrocephaly. We obtained informed consent from the couple. The patient exploded with a female fetus weighing 700 g, her cranial perimeter at 18 cm and thoracic perimeter at 34 cm. A clubfoot was noted on expulsion of the fetus, which is a particular feature of our case.
Abstract: Cyclopia is the most severe form of alobar holoprosencephaly, characterized by the fusion of the two orbits into one. It is a genetic disease incompatible with life. It is most often associated with other craniofacial malformations such as microcephaly, cleft lip and palate, nasal agenesis and facial dysmorphia. The incidence of cyclopia varies fro...
Show More
-
Research Article
Proportion of Low Birth Weight (LBW) Among Newborn Babies Delivered at Dhaka Medical College Hospital
Rukshana Jalil,
Sirajam Munira*,
Sharmeen Sultana,
Beethi Sarker,
Most. Ummey Salma
Issue:
Volume 12, Issue 6, December 2024
Pages:
165-170
Received:
6 October 2024
Accepted:
4 November 2024
Published:
28 November 2024
Abstract: Background: Low birth weight (LBW) remains a major public health problem especially in developing countries like Bangladesh. We assessed the proportion of LBW of the newborn babies delivered at DMCH and its associated maternal factors. Methodology: This cross-sectional descriptive study was conducted among 57 mother and newborn pairs delivered at Postnatal obstetrics wards of Dhaka Medical College Hospital (DMCH), Dhaka. Data was collected from each participants by face to-face interview using a semi-structured pre-tested questionnaire which included socio-demographic information and information about birth weight and its associated maternal factors. Result: This study involved 257 participants with a mean age of 25 years (±4.26), primarily aged 21 to 30 (64.97%). Approximately 38.13% had a monthly family income below 15,000 taka, and 10.98% of mothers were illiterate. One-third received 2 to 4 antenatal visits, with 8.56% having none. Delivery methods were nearly equal, with 49.02% vaginal and 50.97% cesarean. Common complications included PROM (14.39%), pre-term labor (11.67%), and GDM (10.89%). Term pregnancies accounted for 70%, while among preterm births, 20.23% were low birth weight (LBW) and 4.67% very low birth weight (VLBW), surpassing general population rates. Conclusion: Lack of regular antenatal care (ANC) visits and poor maternal diet significantly impact newborn birth weight. To reduce low birth weight (LBW), it is essential to monitor maternal diets and ensure at least four ANC visits for all mothers. LBW infants are at higher risk of mortality and chronic diseases, making its reduction vital for achieving Sustainable Development Goals (SDGs) on infant mortality. Further multi-center studies are needed to accurately assess LBW prevalence in Bangladesh.
Abstract: Background: Low birth weight (LBW) remains a major public health problem especially in developing countries like Bangladesh. We assessed the proportion of LBW of the newborn babies delivered at DMCH and its associated maternal factors. Methodology: This cross-sectional descriptive study was conducted among 57 mother and newborn pairs delivered at P...
Show More
