Tubal factors are associated with infertility. To evaluate the influence of past Chlamydial infections on female fertility with unilateral tubal occlusion, we compared the cumulative pregnancy rate of Chlamydia antibody seropositive women with those who are seronegative. A retrospective, case-controlled study was designed. A total of 54 consecutive infertile women with unilateral tubal occlusion diagnosed by hysterosalpingography (HSG) during January, 2009 to April, 2013 were enrolled in this study. Each patient was followed up for three years. The study group was composed of 19 Chlamydia antibody seropositive women. The control group consisted of 35 who are seronegative. The cumulative pregnancy rate of the study group was 6/19 (31.5%) and that of the control group was 19/35 (54.3%). This suggested that the patients with past Chlamydial infections had more difficulty becoming pregnant than those without prior infections. There were no significant differences of clinical parameters between the two groups. This study suggested that past Chlamydia infection may contribute to lower pregnancy rates in infertile women with unilateral tubal occlusion. Patients with both unilateral tubal occlusion and Chlamydia antibody seropositive may do better to proceed to in vitro fertilization (IVF).
| Published in | Journal of Gynecology and Obstetrics (Volume 4, Issue 6) |
| DOI | 10.11648/j.jgo.20160406.11 |
| Page(s) | 34-37 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2016. Published by Science Publishing Group |
Chlamydia Trachomatis Infection, Unilateral Tubal Occlusion, In Vitro Fertilization (IVF)
| [1] | Haggerty CL, Gottlieb SL, Taylor BD, Low N, Xu F, Ness RB. ‘‘Risk of sequelae after Chlamydia trachomatis genital infection in women’’ J Infect Dis. Vol S1, pp34-55. Jun 2010. |
| [2] | Mascellino MT, Boccia P, Oliva A. ‘‘Immunopathogenesis in Chlamydia trachomatis Infected Women.’’ ISRN Obstet Gynecol, 436936, 2011. |
| [3] | Campbell LA, Patton DL, Moore DE, Cappucio AL. ‘‘Detection of Chlamydia trachomatis deoxyribonucleic acid in women with tubal infertility.” Fertil Steril, Vol 59, pp 45-50, Jan 1993. |
| [4] | Centers for Disease Control (CDC) and Prevention, ‘‘Recommendations for the Laboratory-Based Detection of Chlamydia trachomatis and Neisseria gonorrhoeae.” Vol 63 No2, March 2014. |
| [5] | Farhi J, Ben-Haroush A, Lande Y, Fisch B. ‘‘Role of treatment with ovarian stimulation and intrauterine insemination in women with unilateral tubal occlusion diagnosed by hysterosalpingography.’’ Fertil Steril, Vol 88, pp 396-400, August 2007. |
| [6] | Idahl A, Boman J, Kumlin U, Olofsson JI. “Demonstration of Chlamydia. trachomatis IgG antibodies in the male partner of the infertile couple is correlated with a reduced likelihood of achieving pregnancy.” Hum Reprod. Vol 19, No5, pp 1121-6, 2004. |
| [7] | Denise A. M. Perquin, Matthias F. C. Beersma, Anton J.M.de Craen, Franz M. Helmerhorst, “The value of Chlamydia trachomatis–specific IgG antibody testing and hysterosalpingography for predicting tubal pathology and occurrence of pregnancy.” Fertil Steril. Vol 88, pp 224-6, July 2007. |
| [8] | Batool Hossein Rashidi, Leili Chamani-Tabriz, Fadieh Haghollahi et al. “Effects of Chlamydia trachomatis Infection on Fertility; A Case-Control Study.” J Reprod Infertile, Vol 14, No2, pp 67-72. Apr 2013. |
| [9] | Martin D. Keltz, Puja Sharma Gera. “Chlamydia serology screening in infertility patients.” Fertil Steril. Vol 85, pp 752-4, March 2006. |
| [10] | Practice Committee of the American Society for Reproductive Medicine, Committee opinion “role of tubal surgery in the era of assisted reproductive technology.’’ Fertil Steril. Vol 97, No 3, pp 539-545, Mar 2012. |
| [11] | Broeze KA, Opmeer BC, Van Geloven N, Coppus SF, Collins JA, Den Hartog JE, Van der Linden PJ, Marianowski P, Ng EH, Van der Steeg JW, Steures P, Strandell A, Van der Veen F, Mol BW. ‘‘Are patient characteristics associated with the accuracy of hysterosalpingography in diagnosing tubal pathology? An individual patient data meta-analysis.’’ Hum Reprod Update. Vol 17, No3 pp293-300, May-Jun 2011. |
| [12] | T. J. Laatilainen, A. K, Tenhunen, P. K. Venesmaa, and D. L. Apter. “Factors Influencing the Success of Microsurgery for Distal Tubal Occlusion.” Gynecology and Obstetrics. Vol 243 No2, pp 101-106, 1988. |
| [13] | Mårdh PA. ‘‘Tubal factor infertility, with special regard to chlamydial salpingitis.’’ Curr Opin Infect Dis. Vol 17, No1, pp49-52, Feb 2004. |
| [14] | Mirjana Kessler, Julia Zielecki, Oliver Thieck, et al. ‘‘Chlamydia trachomatis Disturbs Epithelial Tissue Homeostasis in Fallopian Tubes via Paracrine Wnt Signaling.” Am J Pathol. Vol 180, No. 1, pp186-198, January 2012. |
| [15] | Sam vasilevsky, Gillbert Greub, Denise Nardelli-Haefliger, David Baud ‘‘Genital Chlamydia trachomatis: Understanding the Roles of Innate and Adaptive Immunity in Vaccine Research” Clinical Microbiology Reviews Vol 27, No.2, pp 346-370, April 2014. |
APA Style
Satoko Goa, Keiichi Kumasawa, Masaaki Ono, Takeshi Taniguchi. (2016). History of Chlamydia Trachomatis Infection Threatens Fertility in Women with Unilateral Tubal Occlusion. Journal of Gynecology and Obstetrics, 4(6), 34-37. https://doi.org/10.11648/j.jgo.20160406.11
ACS Style
Satoko Goa; Keiichi Kumasawa; Masaaki Ono; Takeshi Taniguchi. History of Chlamydia Trachomatis Infection Threatens Fertility in Women with Unilateral Tubal Occlusion. J. Gynecol. Obstet. 2016, 4(6), 34-37. doi: 10.11648/j.jgo.20160406.11
AMA Style
Satoko Goa, Keiichi Kumasawa, Masaaki Ono, Takeshi Taniguchi. History of Chlamydia Trachomatis Infection Threatens Fertility in Women with Unilateral Tubal Occlusion. J Gynecol Obstet. 2016;4(6):34-37. doi: 10.11648/j.jgo.20160406.11
Share This Article
Twitter
Linked In
Facebook
Copy
Download@article{10.11648/j.jgo.20160406.11,
author = {Satoko Goa and Keiichi Kumasawa and Masaaki Ono and Takeshi Taniguchi},
title = {History of Chlamydia Trachomatis Infection Threatens Fertility in Women with Unilateral Tubal Occlusion},
journal = {Journal of Gynecology and Obstetrics},
volume = {4},
number = {6},
pages = {34-37},
doi = {10.11648/j.jgo.20160406.11},
url = {https://doi.org/10.11648/j.jgo.20160406.11},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jgo.20160406.11},
abstract = {Tubal factors are associated with infertility. To evaluate the influence of past Chlamydial infections on female fertility with unilateral tubal occlusion, we compared the cumulative pregnancy rate of Chlamydia antibody seropositive women with those who are seronegative. A retrospective, case-controlled study was designed. A total of 54 consecutive infertile women with unilateral tubal occlusion diagnosed by hysterosalpingography (HSG) during January, 2009 to April, 2013 were enrolled in this study. Each patient was followed up for three years. The study group was composed of 19 Chlamydia antibody seropositive women. The control group consisted of 35 who are seronegative. The cumulative pregnancy rate of the study group was 6/19 (31.5%) and that of the control group was 19/35 (54.3%). This suggested that the patients with past Chlamydial infections had more difficulty becoming pregnant than those without prior infections. There were no significant differences of clinical parameters between the two groups. This study suggested that past Chlamydia infection may contribute to lower pregnancy rates in infertile women with unilateral tubal occlusion. Patients with both unilateral tubal occlusion and Chlamydia antibody seropositive may do better to proceed to in vitro fertilization (IVF).},
year = {2016}
}
TY - JOUR T1 - History of Chlamydia Trachomatis Infection Threatens Fertility in Women with Unilateral Tubal Occlusion AU - Satoko Goa AU - Keiichi Kumasawa AU - Masaaki Ono AU - Takeshi Taniguchi Y1 - 2016/10/08 PY - 2016 N1 - https://doi.org/10.11648/j.jgo.20160406.11 DO - 10.11648/j.jgo.20160406.11 T2 - Journal of Gynecology and Obstetrics JF - Journal of Gynecology and Obstetrics JO - Journal of Gynecology and Obstetrics SP - 34 EP - 37 PB - Science Publishing Group SN - 2376-7820 UR - https://doi.org/10.11648/j.jgo.20160406.11 AB - Tubal factors are associated with infertility. To evaluate the influence of past Chlamydial infections on female fertility with unilateral tubal occlusion, we compared the cumulative pregnancy rate of Chlamydia antibody seropositive women with those who are seronegative. A retrospective, case-controlled study was designed. A total of 54 consecutive infertile women with unilateral tubal occlusion diagnosed by hysterosalpingography (HSG) during January, 2009 to April, 2013 were enrolled in this study. Each patient was followed up for three years. The study group was composed of 19 Chlamydia antibody seropositive women. The control group consisted of 35 who are seronegative. The cumulative pregnancy rate of the study group was 6/19 (31.5%) and that of the control group was 19/35 (54.3%). This suggested that the patients with past Chlamydial infections had more difficulty becoming pregnant than those without prior infections. There were no significant differences of clinical parameters between the two groups. This study suggested that past Chlamydia infection may contribute to lower pregnancy rates in infertile women with unilateral tubal occlusion. Patients with both unilateral tubal occlusion and Chlamydia antibody seropositive may do better to proceed to in vitro fertilization (IVF). VL - 4 IS - 6 ER -
Information
Email: