Fetomaternal Outcome in Pregnant Women with Acute Hepatitis E

Sadia Asghar; Sadia Maqbool

doi:doi:10.11648/j.jgo.20190706.13

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Fetomaternal Outcome in Pregnant Women with Acute Hepatitis E

Sadia Asghar, Sadia Maqbool

Published in Journal of Gynecology and Obstetrics (Volume 7, Issue 6)

Received: 1 May 2019 Accepted: 21 October 2019 Published: 31 October 2019

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Abstract

Hepatitis E is fairly common among pregnant population and puts a threat to mother and fetal wellbeing. Only limited research is available on association of Hepatitis E infection in pregnancy with feto-maternal outcome. The purpose of the current study was to investigate such patients while carefully eliminating bias by controlling confounders. We aimed to determine the feto-maternal outcome in pregnant women with acute hepatitis E. A descriptive case series was conducted to find feto-maternal outcome in pregnant women with acute hepatitis E. The mean maternal age was 30.05±4.49 years ad mean Gestational age of the patients was 35.73±2.10 months. Most (47%) of the patients were para 3 followed by para 2 (31.8%). 78.8% of the mothers underwent caesarean delivery. Most of the patients had Preterm delivery (69.7%). 16 (24.2%) patients died while majority (75.8%) of the patients survived for more than 30 days after delivery. Most of the mothers (50.0%) died during first 10 days of delivery. 28.8% of patients suffered fetal loss while majority (71.2%) of the neonates survived for more than 7 days. Majority (78.9%) of those who expired died in utero while only a smaller percentage (21.1%) expired in neonatal period. Hepatitis E infection in pregnancy is associated with poor feto-maternal outcome. Careful monitoring and early intervention in the form of caesarean delivery can improve the outcome.

Published in	Journal of Gynecology and Obstetrics (Volume 7, Issue 6)
DOI	10.11648/j.jgo.20190706.13
Page(s)	166-169
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2019. Published by Science Publishing Group

Keywords

Viral Hepatitis, Hepatitis E, Feto-Maternal Outcome

References

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[3]	Kasper L, Fauci J. Actue viral hepatitis Havrison’s princ intern Med. 2015; 2 (18) 2537-2555.
[4]	Lindeman ML, Gabilondo G, Romero B, et al. low prevalence of hepatitis and infection among pregnant women in Madrid spain J Med Virol. 2010; 82: 1666-1668 doi: 10.1002/jmv.201840.
[5]	Purcell R, Emerson S. Hepatitis E: an emerging awareness of an old disease. Journal of hepatology 2008; 48 (3): 494-503.
[6]	Alvi AH, Sabir O, IKram –ul-Haq R, Nawaz AA, Riaz: Acute hepatitits E during pregnancy; maternal and fetal Outcome professional Med. J 2015; 22 (11): 1379-1382 DoI: 10.17957/TPMJ /152748.
[7]	Navaneethan U, Al Mohajer M, Shata MT. Hepatitis E and pregnancy: understanding the pathogenesis. Liver international 2008; 28 (9): 1190-9.
[8]	Rerou C, goket, locher C, moumenA T, timbely O, savany J. Prospective study of hepatis E virus infection among pregnant women in france. virol J 2014; 11: 11-68.
[9]	Borkaoti J, Hazam R J, MOhamad A, kumar A, kar P. Does high viral load of Hepatis E virus infuse the severisity and prognosis of acute level faiure during pregnancy. J Med virol. 2013 april; 85 (4); 620-6. doi: 10.1002/jmv23508. Epub 2012 Dec 26.
[10]	Shrestha NS, Shrestha SK, Singh A, Malla K, Thapa LB. Maternal and perinatal outcome of pregnancy with hepatitis E infection. Journal of South Asian Federation of Obstetrics and Gynecology 2011; 3 (1): 17-20.
[11]	Mansoor M, Raza H, Tariq R. Feto-maternal outcome in HEV infection. Annals of King Edward Medical University 2011; 17 (1): 86-90.
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[14]	Kose V, Joshi S. Pregnancy Outcome in Viral Hepatitis. Journal of South Asian Federation of Obstetrics and Gynaecology 2013; 5 (2): 60-3.
[15]	Bassam AA, Ahmed Y. Outcome of Viral Hepatitis in pregnancy. J Iraq Gastroent 2007; 1 (2): 48-53.
[16]	Yasmeen T, Hashmi HA, Taj A. Fetomaternal outcome with hepatitis e in pregnancy. J Coll Physicians Surg Pak 2013; 23 (10): 711-4.

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APA Style

Sadia Asghar, Sadia Maqbool. (2019). Fetomaternal Outcome in Pregnant Women with Acute Hepatitis E. Journal of Gynecology and Obstetrics, 7(6), 166-169. https://doi.org/10.11648/j.jgo.20190706.13

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ACS Style

Sadia Asghar; Sadia Maqbool. Fetomaternal Outcome in Pregnant Women with Acute Hepatitis E. J. Gynecol. Obstet. 2019, 7(6), 166-169. doi: 10.11648/j.jgo.20190706.13

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AMA Style

Sadia Asghar, Sadia Maqbool. Fetomaternal Outcome in Pregnant Women with Acute Hepatitis E. J Gynecol Obstet. 2019;7(6):166-169. doi: 10.11648/j.jgo.20190706.13

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@article{10.11648/j.jgo.20190706.13,
  author = {Sadia Asghar and Sadia Maqbool},
  title = {Fetomaternal Outcome in Pregnant Women with Acute Hepatitis E},
  journal = {Journal of Gynecology and Obstetrics},
  volume = {7},
  number = {6},
  pages = {166-169},
  doi = {10.11648/j.jgo.20190706.13},
  url = {https://doi.org/10.11648/j.jgo.20190706.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jgo.20190706.13},
  abstract = {Hepatitis E is fairly common among pregnant population and puts a threat to mother and fetal wellbeing. Only limited research is available on association of Hepatitis E infection in pregnancy with feto-maternal outcome. The purpose of the current study was to investigate such patients while carefully eliminating bias by controlling confounders. We aimed to determine the feto-maternal outcome in pregnant women with acute hepatitis E. A descriptive case series was conducted to find feto-maternal outcome in pregnant women with acute hepatitis E. The mean maternal age was 30.05±4.49 years ad mean Gestational age of the patients was 35.73±2.10 months. Most (47%) of the patients were para 3 followed by para 2 (31.8%). 78.8% of the mothers underwent caesarean delivery. Most of the patients had Preterm delivery (69.7%). 16 (24.2%) patients died while majority (75.8%) of the patients survived for more than 30 days after delivery. Most of the mothers (50.0%) died during first 10 days of delivery. 28.8% of patients suffered fetal loss while majority (71.2%) of the neonates survived for more than 7 days. Majority (78.9%) of those who expired died in utero while only a smaller percentage (21.1%) expired in neonatal period. Hepatitis E infection in pregnancy is associated with poor feto-maternal outcome. Careful monitoring and early intervention in the form of caesarean delivery can improve the outcome.},
 year = {2019}
}

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TY - JOUR
T1 - Fetomaternal Outcome in Pregnant Women with Acute Hepatitis E
AU - Sadia Asghar
AU - Sadia Maqbool
Y1 - 2019/10/31
PY - 2019
N1 - https://doi.org/10.11648/j.jgo.20190706.13
DO - 10.11648/j.jgo.20190706.13
T2 - Journal of Gynecology and Obstetrics
JF - Journal of Gynecology and Obstetrics
JO - Journal of Gynecology and Obstetrics
SP - 166
EP - 169
PB - Science Publishing Group
SN - 2376-7820
UR - https://doi.org/10.11648/j.jgo.20190706.13
AB - Hepatitis E is fairly common among pregnant population and puts a threat to mother and fetal wellbeing. Only limited research is available on association of Hepatitis E infection in pregnancy with feto-maternal outcome. The purpose of the current study was to investigate such patients while carefully eliminating bias by controlling confounders. We aimed to determine the feto-maternal outcome in pregnant women with acute hepatitis E. A descriptive case series was conducted to find feto-maternal outcome in pregnant women with acute hepatitis E. The mean maternal age was 30.05±4.49 years ad mean Gestational age of the patients was 35.73±2.10 months. Most (47%) of the patients were para 3 followed by para 2 (31.8%). 78.8% of the mothers underwent caesarean delivery. Most of the patients had Preterm delivery (69.7%). 16 (24.2%) patients died while majority (75.8%) of the patients survived for more than 30 days after delivery. Most of the mothers (50.0%) died during first 10 days of delivery. 28.8% of patients suffered fetal loss while majority (71.2%) of the neonates survived for more than 7 days. Majority (78.9%) of those who expired died in utero while only a smaller percentage (21.1%) expired in neonatal period. Hepatitis E infection in pregnancy is associated with poor feto-maternal outcome. Careful monitoring and early intervention in the form of caesarean delivery can improve the outcome.
VL - 7
IS - 6
ER -

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Author Information

Sadia Asghar

Department of Obstetrics and Gynecology, Rai Medical College, Sargodha, Pakistan
Sadia Maqbool

Department of Obstetrics and Gynecology, Ganga Ram Hospital, Lahore, Pakistan

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Plain Text BibTeX RIS

APA Style

Sadia Asghar, Sadia Maqbool. (2019). Fetomaternal Outcome in Pregnant Women with Acute Hepatitis E. Journal of Gynecology and Obstetrics, 7(6), 166-169. https://doi.org/10.11648/j.jgo.20190706.13

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ACS Style

Sadia Asghar; Sadia Maqbool. Fetomaternal Outcome in Pregnant Women with Acute Hepatitis E. J. Gynecol. Obstet. 2019, 7(6), 166-169. doi: 10.11648/j.jgo.20190706.13

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AMA Style

Sadia Asghar, Sadia Maqbool. Fetomaternal Outcome in Pregnant Women with Acute Hepatitis E. J Gynecol Obstet. 2019;7(6):166-169. doi: 10.11648/j.jgo.20190706.13

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@article{10.11648/j.jgo.20190706.13,
  author = {Sadia Asghar and Sadia Maqbool},
  title = {Fetomaternal Outcome in Pregnant Women with Acute Hepatitis E},
  journal = {Journal of Gynecology and Obstetrics},
  volume = {7},
  number = {6},
  pages = {166-169},
  doi = {10.11648/j.jgo.20190706.13},
  url = {https://doi.org/10.11648/j.jgo.20190706.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jgo.20190706.13},
  abstract = {Hepatitis E is fairly common among pregnant population and puts a threat to mother and fetal wellbeing. Only limited research is available on association of Hepatitis E infection in pregnancy with feto-maternal outcome. The purpose of the current study was to investigate such patients while carefully eliminating bias by controlling confounders. We aimed to determine the feto-maternal outcome in pregnant women with acute hepatitis E. A descriptive case series was conducted to find feto-maternal outcome in pregnant women with acute hepatitis E. The mean maternal age was 30.05±4.49 years ad mean Gestational age of the patients was 35.73±2.10 months. Most (47%) of the patients were para 3 followed by para 2 (31.8%). 78.8% of the mothers underwent caesarean delivery. Most of the patients had Preterm delivery (69.7%). 16 (24.2%) patients died while majority (75.8%) of the patients survived for more than 30 days after delivery. Most of the mothers (50.0%) died during first 10 days of delivery. 28.8% of patients suffered fetal loss while majority (71.2%) of the neonates survived for more than 7 days. Majority (78.9%) of those who expired died in utero while only a smaller percentage (21.1%) expired in neonatal period. Hepatitis E infection in pregnancy is associated with poor feto-maternal outcome. Careful monitoring and early intervention in the form of caesarean delivery can improve the outcome.},
 year = {2019}
}

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