Background: Pregnant women are exposed to toxic trace elements (TE) from mining plants. The aim of this study was to determine the incidence of morbid conditions among pregnant women and their relations to blood’s concentration of TE and their exposure factors in Lubumbashi. Methodology: A prospective cohort study of 378 mothers and 378 newborns exposed to TE was conducted from November 30, 2018, to May 30, 2019. The groups were constituted whether the TE concentration was higher or lower than the reference value. (Determined by ICP- OES Optima 8300 at the laboratory of the OCC/Lubumbashi). Correlation between the morbid conditions in the two groups and with each exposure factors by calculating chi square and the relative risk were obtained. (p ˂ 0.05) Results: Among pregnant women 61.4% had malaria, 47.6% anemia, 21.2% hypertension, 11% IUGR newborns and 8.7% a premature birth. Geophagia increased two times the risk of anemia [RR: 2.127 (1.410-3.209)] and hypertension [RR: 1.958 (1.177-3.259)]. The proximity to mining plants increased three times the risk of anemia [RR: 2.887 (1.830-5.554)] and hypertension [RR: 3.126 (1.876-5.208)]. The use of well water for drinking and housework increased two times the risk of hypertension [RR: 2.308 (1.385-3.845)] and IUGR newborn [RR: 1.752 (1.232-2.490)]. Biomass used for cooking increased three times the risk of hypertension [RR: 3.204 (1.114-9.212)]. Women working in mining plants had two times the risk of malaria: [RR 1.725 (1.145-2.599)]. Women whose husband worked in mining plants had three times the risk of premature birth [RR: 3.204 (1.552-6.616)]. High lead concentration increased five times the risk of anemia [RR: 4.63 (2.933-7.310)]; height times the risk of hypertension [RR: 8.170 (4.657-14.333)]; three times the risk of a IUGR newborn [RR: 2.601 (2.078-3.256)]. The linear correlation between lead and maternal hemoglobin was negative (r -0.335). High maternal concentration of cobalt, arsenic and cadmium increased two times the risk of hypertension. High maternal magnesium and high neonate cadmium concentrations increased two times the risk of premature births. High neonate lead, cobalt, zinc, and magnesium’ concentrations increased two times the risk of maternal anemia. But high neonate selenium concentration reduced to 60% [RR: 0.59 (0.360-0.978)] this risk. Low neonate selenium concentration increased four times the risk of IUGR neonate [RR: 4.116 (2.004-8.452)]. Conclusion: High concentration of toxic TE and low concentration of some essential TE in the blood of pregnant women are associated to morbid conditions such as anemia, malaria, maternal hypertension, IUGR and prematurity.
| Published in | Journal of Gynecology and Obstetrics (Volume 10, Issue 5) |
| DOI | 10.11648/j.jgo.20221005.12 |
| Page(s) | 221-230 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2022. Published by Science Publishing Group |
Trace Elements, Maternal Morbidity, Exposure Factors, Mining Plants, Lubumbashi
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APA Style
Cham Lubamba Chamy, Mwembo Tambwe Albert, Ngwe Thaba Jules, Kakudji Luhete Prosper, Mpoyo Wembonyama, et al. (2022). Maternal Morbidity Associated to Exposure to Trace Elements in Lubumbashi. Journal of Gynecology and Obstetrics, 10(5), 221-230. https://doi.org/10.11648/j.jgo.20221005.12
ACS Style
Cham Lubamba Chamy; Mwembo Tambwe Albert; Ngwe Thaba Jules; Kakudji Luhete Prosper; Mpoyo Wembonyama, et al. Maternal Morbidity Associated to Exposure to Trace Elements in Lubumbashi. J. Gynecol. Obstet. 2022, 10(5), 221-230. doi: 10.11648/j.jgo.20221005.12
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author = {Cham Lubamba Chamy and Mwembo Tambwe Albert and Ngwe Thaba Jules and Kakudji Luhete Prosper and Mpoyo Wembonyama and Mukendi Mutshimbe Richard and Momat Kitenge Felix and Kimbala Shimpiko Julien and Nsambi Bulanda Jospeh and Malonga Kaj Francoise and Kaniki Tshamala Arthur and Kinekinda Kalume Xavier and Kalenga Muenze Kayamba and Kakoma Sakatolo Zambeze},
title = {Maternal Morbidity Associated to Exposure to Trace Elements in Lubumbashi},
journal = {Journal of Gynecology and Obstetrics},
volume = {10},
number = {5},
pages = {221-230},
doi = {10.11648/j.jgo.20221005.12},
url = {https://doi.org/10.11648/j.jgo.20221005.12},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jgo.20221005.12},
abstract = {Background: Pregnant women are exposed to toxic trace elements (TE) from mining plants. The aim of this study was to determine the incidence of morbid conditions among pregnant women and their relations to blood’s concentration of TE and their exposure factors in Lubumbashi. Methodology: A prospective cohort study of 378 mothers and 378 newborns exposed to TE was conducted from November 30, 2018, to May 30, 2019. The groups were constituted whether the TE concentration was higher or lower than the reference value. (Determined by ICP- OES Optima 8300 at the laboratory of the OCC/Lubumbashi). Correlation between the morbid conditions in the two groups and with each exposure factors by calculating chi square and the relative risk were obtained. (p ˂ 0.05) Results: Among pregnant women 61.4% had malaria, 47.6% anemia, 21.2% hypertension, 11% IUGR newborns and 8.7% a premature birth. Geophagia increased two times the risk of anemia [RR: 2.127 (1.410-3.209)] and hypertension [RR: 1.958 (1.177-3.259)]. The proximity to mining plants increased three times the risk of anemia [RR: 2.887 (1.830-5.554)] and hypertension [RR: 3.126 (1.876-5.208)]. The use of well water for drinking and housework increased two times the risk of hypertension [RR: 2.308 (1.385-3.845)] and IUGR newborn [RR: 1.752 (1.232-2.490)]. Biomass used for cooking increased three times the risk of hypertension [RR: 3.204 (1.114-9.212)]. Women working in mining plants had two times the risk of malaria: [RR 1.725 (1.145-2.599)]. Women whose husband worked in mining plants had three times the risk of premature birth [RR: 3.204 (1.552-6.616)]. High lead concentration increased five times the risk of anemia [RR: 4.63 (2.933-7.310)]; height times the risk of hypertension [RR: 8.170 (4.657-14.333)]; three times the risk of a IUGR newborn [RR: 2.601 (2.078-3.256)]. The linear correlation between lead and maternal hemoglobin was negative (r -0.335). High maternal concentration of cobalt, arsenic and cadmium increased two times the risk of hypertension. High maternal magnesium and high neonate cadmium concentrations increased two times the risk of premature births. High neonate lead, cobalt, zinc, and magnesium’ concentrations increased two times the risk of maternal anemia. But high neonate selenium concentration reduced to 60% [RR: 0.59 (0.360-0.978)] this risk. Low neonate selenium concentration increased four times the risk of IUGR neonate [RR: 4.116 (2.004-8.452)]. Conclusion: High concentration of toxic TE and low concentration of some essential TE in the blood of pregnant women are associated to morbid conditions such as anemia, malaria, maternal hypertension, IUGR and prematurity.},
year = {2022}
}
TY - JOUR T1 - Maternal Morbidity Associated to Exposure to Trace Elements in Lubumbashi AU - Cham Lubamba Chamy AU - Mwembo Tambwe Albert AU - Ngwe Thaba Jules AU - Kakudji Luhete Prosper AU - Mpoyo Wembonyama AU - Mukendi Mutshimbe Richard AU - Momat Kitenge Felix AU - Kimbala Shimpiko Julien AU - Nsambi Bulanda Jospeh AU - Malonga Kaj Francoise AU - Kaniki Tshamala Arthur AU - Kinekinda Kalume Xavier AU - Kalenga Muenze Kayamba AU - Kakoma Sakatolo Zambeze Y1 - 2022/09/27 PY - 2022 N1 - https://doi.org/10.11648/j.jgo.20221005.12 DO - 10.11648/j.jgo.20221005.12 T2 - Journal of Gynecology and Obstetrics JF - Journal of Gynecology and Obstetrics JO - Journal of Gynecology and Obstetrics SP - 221 EP - 230 PB - Science Publishing Group SN - 2376-7820 UR - https://doi.org/10.11648/j.jgo.20221005.12 AB - Background: Pregnant women are exposed to toxic trace elements (TE) from mining plants. The aim of this study was to determine the incidence of morbid conditions among pregnant women and their relations to blood’s concentration of TE and their exposure factors in Lubumbashi. Methodology: A prospective cohort study of 378 mothers and 378 newborns exposed to TE was conducted from November 30, 2018, to May 30, 2019. The groups were constituted whether the TE concentration was higher or lower than the reference value. (Determined by ICP- OES Optima 8300 at the laboratory of the OCC/Lubumbashi). Correlation between the morbid conditions in the two groups and with each exposure factors by calculating chi square and the relative risk were obtained. (p ˂ 0.05) Results: Among pregnant women 61.4% had malaria, 47.6% anemia, 21.2% hypertension, 11% IUGR newborns and 8.7% a premature birth. Geophagia increased two times the risk of anemia [RR: 2.127 (1.410-3.209)] and hypertension [RR: 1.958 (1.177-3.259)]. The proximity to mining plants increased three times the risk of anemia [RR: 2.887 (1.830-5.554)] and hypertension [RR: 3.126 (1.876-5.208)]. The use of well water for drinking and housework increased two times the risk of hypertension [RR: 2.308 (1.385-3.845)] and IUGR newborn [RR: 1.752 (1.232-2.490)]. Biomass used for cooking increased three times the risk of hypertension [RR: 3.204 (1.114-9.212)]. Women working in mining plants had two times the risk of malaria: [RR 1.725 (1.145-2.599)]. Women whose husband worked in mining plants had three times the risk of premature birth [RR: 3.204 (1.552-6.616)]. High lead concentration increased five times the risk of anemia [RR: 4.63 (2.933-7.310)]; height times the risk of hypertension [RR: 8.170 (4.657-14.333)]; three times the risk of a IUGR newborn [RR: 2.601 (2.078-3.256)]. The linear correlation between lead and maternal hemoglobin was negative (r -0.335). High maternal concentration of cobalt, arsenic and cadmium increased two times the risk of hypertension. High maternal magnesium and high neonate cadmium concentrations increased two times the risk of premature births. High neonate lead, cobalt, zinc, and magnesium’ concentrations increased two times the risk of maternal anemia. But high neonate selenium concentration reduced to 60% [RR: 0.59 (0.360-0.978)] this risk. Low neonate selenium concentration increased four times the risk of IUGR neonate [RR: 4.116 (2.004-8.452)]. Conclusion: High concentration of toxic TE and low concentration of some essential TE in the blood of pregnant women are associated to morbid conditions such as anemia, malaria, maternal hypertension, IUGR and prematurity. VL - 10 IS - 5 ER -
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