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Management of Bilateral Borderline Ovarian Tumor in a 26-year-old Patient in a Resource-Limited Setting

Received: 19 April 2024     Accepted: 8 May 2024     Published: 20 May 2024
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Abstract

Background: borderline ovarian tumors are rare epithelial tumors, more common before the age of 40, with challenging preoperative diagnosis. Our aim is to describe the management of a case in a resource-limited context in Burkina Faso. Case report: a 26-year-old primigravida with a 4-year-old child presented with an abdominal mass evolving over one year in the context of secondary amenorrhea. Clinical examination revealed weight loss, cutaneous-mucosal pallor, increased abdominal volume with tender deep palpation, and an irregular, mildly firm mass around the umbilicus extending to the iliac fossae, with a depressed area along the midline. Speculum examination was normal. On vaginal examination, the cervix was unremarkable, the uterus was of normal size, but the lateral fornices and Douglas pouch were filled. Further investigations revealed microcytic hypochromic anemia and a borderline normal CA 125 level. The rest of the laboratory tests were normal. Abdominal and pelvic ultrasound and CT revealed a strong suspicion of a bilateral ovarian tumour, with no signs of secondary localisation. MRI was not available. The diagnosis of probably malignant bilateral ovarian tumour was retained, and laparotomy was indicated. When the parietal peritoneum was opened, two ovarian tumours with a budding appearance occupied the entire lower half of the abdomen. A part of the omentum was in contact with both masses. Bilateral adnexectomy, total hysterectomy and partial omentectomy were performed in the absence of an extemporaneous histological study. Histological study of the surgical specimens concluded that the tumour was borderline ovarian. Follow-up at 3 years showed no signs of recurrence or tumour extension. Conclusion: borderline ovarian tumours are managed surgically, and the choice of conservative or radical surgery is not easy when there is a desire to have children, and when the ovaries are bilaterally involved. Fortunately, the vital prognosis is favourable.

Published in Journal of Gynecology and Obstetrics (Volume 12, Issue 3)
DOI 10.11648/j.jgo.20241203.11
Page(s) 52-56
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Ovary, Borderline Tumour, Abdominal Mass, Amenorrhoea, Burkina Faso

References
[1] Morice P, Camatte S, Pautier P, Lhommé C, Duvillard P, Castaigne D. Pronostic factors and treatment of borderline ovarian tumors. La Lettre du Cancérologue - Volume XIV - n° 5 - septembre-octobre 2005. p 228-39.
[2] Childress KJ, Patil NM, Muscal JA, Dietrich JE, Venkatramani R. Borderline Ovarian Tumor in the Pediatric and Adolescent Population: A Case Series and Literature Review. J Pediatr Adolesc Gynecol. févr 2018; 31(1): 48-54.
[3] Querleu D, Leblanc E, Dubreucq S, Narducci F, Papageorgiou T, Lambaudie E. Early stage borderline ovarian tumours. La Lettre du Gynécologue - n° 272 - mai 2002; p 19-25.
[4] Della Corte L, Mercorio A, Serafino P, Viciglione F, Palumbo M, De Angelis MC, Borgo M, Buonfantino C, Tesorone M, Bifulco G, Giampaolino P. The challenging management of borderline ovarian tumors (BOTs) in women of childbearing age. Front Surg. 2022 Aug 23; 9: 973034.
[5] Morice P, Camatte S, Lhommé C, Pautier P, Duvillard P, Castaigne D. Prognostic factors and surgical treatment of borderline ovarian tumours. In: Ovarian cancers. Paris: Springer-Verlag; 2006. p. 447-64.
[6] Chaqchaq Z. Borderline ovarian tumours (About 14 cases). Doctoral thesis, Hassane II University, 2016.
[7] Xu M, Wang B, Shi Y. Borderline ovarian tumor in the pediatric and adolescent population: a clinopathologic analysis of fourteen cases. Int J Clin Exp Pathol. 2020; 13(5): 1053-9.
[8] Basse-Normandie Regional Cancer Network. Rare malignant ovarian tumors: diagnostic and therapeutic management. Consulted on February 4, 2023, at:
[9] Eymerit-Morin C, Brun JL, Vabret O, Devouassoux-Shisheboran M. Borderline ovarian tumours: CNGOF Guidelines for clinical practice – Biopathology of ovarian borderline tumors. Gynécologie Obstétrique Fertil Sénologie. mars 2020; 48(3): 304-13.
[10] Duvillard P. Classification anatomopathologiques des tumeurs de l’ovaire, Reproduction humaine et hormones 1998; 11: 619-28.
[11] Franceschia T, Devouassoux-Shisheborana M, Ovarian carcinomas histoseminar. Case 1. Consulted on February 4, 2023, at:
[12] Trillsch F, Mahner S, Woelber L, Vettorazzi E, Reuss A, Ewald-Riegler N, et al. Age-dependent differences in borderline ovarian tumours (BOT) regarding clinical characteristics and outcome: results from a sub-analysis of the Arbeitsgemeinschaft Gynaekologische Onkologie (AGO) ROBOT study. Ann Oncol Off J Eur Soc Med Oncol. juill 2014; 25(7): 1320-7.
[13] Carbonnel M, Layoun L, Poulain M, Tourne M, Murtada R, Grynberg M, Feki A, Ayoubi JM. Serous borderline ovarian tumor diagnosis, management and fertility preservation in young women. J Clin Med. 2021 Sep 18; 10(18): 4233.
[14] Malpica A, Longacre TA. Prognostic indicators in ovarian serous borderline tumours. Pathology (Phila). febr 2018; 50(2): 205-13.
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    Sib, S. R., Savadogo, I., Sanogo, M., Ouedraogo, I., Ouedraogo, S., et al. (2024). Management of Bilateral Borderline Ovarian Tumor in a 26-year-old Patient in a Resource-Limited Setting. Journal of Gynecology and Obstetrics, 12(3), 52-56. https://doi.org/10.11648/j.jgo.20241203.11

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    ACS Style

    Sib, S. R.; Savadogo, I.; Sanogo, M.; Ouedraogo, I.; Ouedraogo, S., et al. Management of Bilateral Borderline Ovarian Tumor in a 26-year-old Patient in a Resource-Limited Setting. J. Gynecol. Obstet. 2024, 12(3), 52-56. doi: 10.11648/j.jgo.20241203.11

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    AMA Style

    Sib SR, Savadogo I, Sanogo M, Ouedraogo I, Ouedraogo S, et al. Management of Bilateral Borderline Ovarian Tumor in a 26-year-old Patient in a Resource-Limited Setting. J Gynecol Obstet. 2024;12(3):52-56. doi: 10.11648/j.jgo.20241203.11

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  • @article{10.11648/j.jgo.20241203.11,
      author = {Sansan Rodrigue Sib and Ibrahim Savadogo and Moussa Sanogo and Issa Ouedraogo and Salam Ouedraogo and Alexandre Tarnagada and Françoise Millogo/Traore and Ali Ouedraogo},
      title = {Management of Bilateral Borderline Ovarian Tumor in a 26-year-old Patient in a Resource-Limited Setting
    },
      journal = {Journal of Gynecology and Obstetrics},
      volume = {12},
      number = {3},
      pages = {52-56},
      doi = {10.11648/j.jgo.20241203.11},
      url = {https://doi.org/10.11648/j.jgo.20241203.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jgo.20241203.11},
      abstract = {Background: borderline ovarian tumors are rare epithelial tumors, more common before the age of 40, with challenging preoperative diagnosis. Our aim is to describe the management of a case in a resource-limited context in Burkina Faso. Case report: a 26-year-old primigravida with a 4-year-old child presented with an abdominal mass evolving over one year in the context of secondary amenorrhea. Clinical examination revealed weight loss, cutaneous-mucosal pallor, increased abdominal volume with tender deep palpation, and an irregular, mildly firm mass around the umbilicus extending to the iliac fossae, with a depressed area along the midline. Speculum examination was normal. On vaginal examination, the cervix was unremarkable, the uterus was of normal size, but the lateral fornices and Douglas pouch were filled. Further investigations revealed microcytic hypochromic anemia and a borderline normal CA 125 level. The rest of the laboratory tests were normal. Abdominal and pelvic ultrasound and CT revealed a strong suspicion of a bilateral ovarian tumour, with no signs of secondary localisation. MRI was not available. The diagnosis of probably malignant bilateral ovarian tumour was retained, and laparotomy was indicated. When the parietal peritoneum was opened, two ovarian tumours with a budding appearance occupied the entire lower half of the abdomen. A part of the omentum was in contact with both masses. Bilateral adnexectomy, total hysterectomy and partial omentectomy were performed in the absence of an extemporaneous histological study. Histological study of the surgical specimens concluded that the tumour was borderline ovarian. Follow-up at 3 years showed no signs of recurrence or tumour extension. Conclusion: borderline ovarian tumours are managed surgically, and the choice of conservative or radical surgery is not easy when there is a desire to have children, and when the ovaries are bilaterally involved. Fortunately, the vital prognosis is favourable.
    },
     year = {2024}
    }
    

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    T1  - Management of Bilateral Borderline Ovarian Tumor in a 26-year-old Patient in a Resource-Limited Setting
    
    AU  - Sansan Rodrigue Sib
    AU  - Ibrahim Savadogo
    AU  - Moussa Sanogo
    AU  - Issa Ouedraogo
    AU  - Salam Ouedraogo
    AU  - Alexandre Tarnagada
    AU  - Françoise Millogo/Traore
    AU  - Ali Ouedraogo
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    JF  - Journal of Gynecology and Obstetrics
    JO  - Journal of Gynecology and Obstetrics
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    EP  - 56
    PB  - Science Publishing Group
    SN  - 2376-7820
    UR  - https://doi.org/10.11648/j.jgo.20241203.11
    AB  - Background: borderline ovarian tumors are rare epithelial tumors, more common before the age of 40, with challenging preoperative diagnosis. Our aim is to describe the management of a case in a resource-limited context in Burkina Faso. Case report: a 26-year-old primigravida with a 4-year-old child presented with an abdominal mass evolving over one year in the context of secondary amenorrhea. Clinical examination revealed weight loss, cutaneous-mucosal pallor, increased abdominal volume with tender deep palpation, and an irregular, mildly firm mass around the umbilicus extending to the iliac fossae, with a depressed area along the midline. Speculum examination was normal. On vaginal examination, the cervix was unremarkable, the uterus was of normal size, but the lateral fornices and Douglas pouch were filled. Further investigations revealed microcytic hypochromic anemia and a borderline normal CA 125 level. The rest of the laboratory tests were normal. Abdominal and pelvic ultrasound and CT revealed a strong suspicion of a bilateral ovarian tumour, with no signs of secondary localisation. MRI was not available. The diagnosis of probably malignant bilateral ovarian tumour was retained, and laparotomy was indicated. When the parietal peritoneum was opened, two ovarian tumours with a budding appearance occupied the entire lower half of the abdomen. A part of the omentum was in contact with both masses. Bilateral adnexectomy, total hysterectomy and partial omentectomy were performed in the absence of an extemporaneous histological study. Histological study of the surgical specimens concluded that the tumour was borderline ovarian. Follow-up at 3 years showed no signs of recurrence or tumour extension. Conclusion: borderline ovarian tumours are managed surgically, and the choice of conservative or radical surgery is not easy when there is a desire to have children, and when the ovaries are bilaterally involved. Fortunately, the vital prognosis is favourable.
    
    VL  - 12
    IS  - 3
    ER  - 

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Author Information
  • Health Sciences Training and Research Unit, Ouahigouya University, Ouahigouya, Burkina Faso

  • Health Sciences Training and Research Unit, Ouahigouya University, Ouahigouya, Burkina Faso

  • Department of Obstetrics and Gynecology, Ouahigouya Regional University Hospital, Ouahigouya, Burkina Faso

  • Health Sciences Training and Research Unit, Ouahigouya University, Ouahigouya, Burkina Faso

  • Health Sciences Training and Research Unit, Ouahigouya University, Ouahigouya, Burkina Faso

  • Department of Obstetrics and Gynecology, Ouahigouya Regional University Hospital, Ouahigouya, Burkina Faso

  • Health Sciences Training and Research Unit, Joseph Ki-Zerbo University, Ouagadougou, Burkina Faso

  • Health Sciences Training and Research Unit, Joseph Ki-Zerbo University, Ouagadougou, Burkina Faso

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