,
Kiemtore Sibraogo,
Traore Solo,
Sawadogo Zakaria,
Ouedraogo Mahamoudou,
Dao Blami
Cyclopia is the most severe form of alobar holoprosencephaly, characterized by the fusion of the two orbits into one. It is a genetic disease incompatible with life. It is most often associated with other craniofacial malformations such as microcephaly, cleft lip and palate, nasal agenesis and facial dysmorphia. The incidence of cyclopia varies from 1/13,000 to 1/20,000 births, and the etiology of this malformation has yet to be elucidated. These include genetic factors, multiparity, female gender, unexplained miscarriage, gestational diabetes, infections during pregnancy, UV radiation, smoking and alcohol consumption. It is probably less diagnosed in developing countries, where pregnancies are not normally monitored, and antenatal ultrasound is less common. We report the case of a 22-year-old pregnant woman, third gesture and two pares with two live children. She came on her own for a third-trimester ultrasound. She had a spontaneous pregnancy. She reported no previous history of a spontaneous pregnancy. Morphological ultrasound revealed cyclopia associated with microcephaly and hydrocephaly. We obtained informed consent from the couple. The patient exploded with a female fetus weighing 700 g, her cranial perimeter at 18 cm and thoracic perimeter at 34 cm. A clubfoot was noted on expulsion of the fetus, which is a particular feature of our case.
| Published in | Journal of Gynecology and Obstetrics (Volume 12, Issue 6) |
| DOI | 10.11648/j.jgo.20241206.15 |
| Page(s) | 161-164 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Cyclopia, Holoprosencephaly, Hydrocephaly, Burkina Faso
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APA Style
Dieudonne, L. Y., Sibraogo, K., Solo, T., Zakaria, S., Mahamoudou, O., et al. (2024). Cyclopia Associated with Microcephaly, Hydrocephaly and Clubfoot: A Case Report from Burkina Faso, West Africa. Journal of Gynecology and Obstetrics, 12(6), 161-164. https://doi.org/10.11648/j.jgo.20241206.15
ACS Style
Dieudonne, L. Y.; Sibraogo, K.; Solo, T.; Zakaria, S.; Mahamoudou, O., et al. Cyclopia Associated with Microcephaly, Hydrocephaly and Clubfoot: A Case Report from Burkina Faso, West Africa. J. Gynecol. Obstet. 2024, 12(6), 161-164. doi: 10.11648/j.jgo.20241206.15
AMA Style
Dieudonne LY, Sibraogo K, Solo T, Zakaria S, Mahamoudou O, et al. Cyclopia Associated with Microcephaly, Hydrocephaly and Clubfoot: A Case Report from Burkina Faso, West Africa. J Gynecol Obstet. 2024;12(6):161-164. doi: 10.11648/j.jgo.20241206.15
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Download@article{10.11648/j.jgo.20241206.15,
author = {Lompo Yemboado Dieudonne and Kiemtore Sibraogo and Traore Solo and Sawadogo Zakaria and Ouedraogo Mahamoudou and Dao Blami},
title = {Cyclopia Associated with Microcephaly, Hydrocephaly and Clubfoot: A Case Report from Burkina Faso, West Africa
},
journal = {Journal of Gynecology and Obstetrics},
volume = {12},
number = {6},
pages = {161-164},
doi = {10.11648/j.jgo.20241206.15},
url = {https://doi.org/10.11648/j.jgo.20241206.15},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jgo.20241206.15},
abstract = {Cyclopia is the most severe form of alobar holoprosencephaly, characterized by the fusion of the two orbits into one. It is a genetic disease incompatible with life. It is most often associated with other craniofacial malformations such as microcephaly, cleft lip and palate, nasal agenesis and facial dysmorphia. The incidence of cyclopia varies from 1/13,000 to 1/20,000 births, and the etiology of this malformation has yet to be elucidated. These include genetic factors, multiparity, female gender, unexplained miscarriage, gestational diabetes, infections during pregnancy, UV radiation, smoking and alcohol consumption. It is probably less diagnosed in developing countries, where pregnancies are not normally monitored, and antenatal ultrasound is less common. We report the case of a 22-year-old pregnant woman, third gesture and two pares with two live children. She came on her own for a third-trimester ultrasound. She had a spontaneous pregnancy. She reported no previous history of a spontaneous pregnancy. Morphological ultrasound revealed cyclopia associated with microcephaly and hydrocephaly. We obtained informed consent from the couple. The patient exploded with a female fetus weighing 700 g, her cranial perimeter at 18 cm and thoracic perimeter at 34 cm. A clubfoot was noted on expulsion of the fetus, which is a particular feature of our case.
},
year = {2024}
}
TY - JOUR T1 - Cyclopia Associated with Microcephaly, Hydrocephaly and Clubfoot: A Case Report from Burkina Faso, West Africa AU - Lompo Yemboado Dieudonne AU - Kiemtore Sibraogo AU - Traore Solo AU - Sawadogo Zakaria AU - Ouedraogo Mahamoudou AU - Dao Blami Y1 - 2024/11/28 PY - 2024 N1 - https://doi.org/10.11648/j.jgo.20241206.15 DO - 10.11648/j.jgo.20241206.15 T2 - Journal of Gynecology and Obstetrics JF - Journal of Gynecology and Obstetrics JO - Journal of Gynecology and Obstetrics SP - 161 EP - 164 PB - Science Publishing Group SN - 2376-7820 UR - https://doi.org/10.11648/j.jgo.20241206.15 AB - Cyclopia is the most severe form of alobar holoprosencephaly, characterized by the fusion of the two orbits into one. It is a genetic disease incompatible with life. It is most often associated with other craniofacial malformations such as microcephaly, cleft lip and palate, nasal agenesis and facial dysmorphia. The incidence of cyclopia varies from 1/13,000 to 1/20,000 births, and the etiology of this malformation has yet to be elucidated. These include genetic factors, multiparity, female gender, unexplained miscarriage, gestational diabetes, infections during pregnancy, UV radiation, smoking and alcohol consumption. It is probably less diagnosed in developing countries, where pregnancies are not normally monitored, and antenatal ultrasound is less common. We report the case of a 22-year-old pregnant woman, third gesture and two pares with two live children. She came on her own for a third-trimester ultrasound. She had a spontaneous pregnancy. She reported no previous history of a spontaneous pregnancy. Morphological ultrasound revealed cyclopia associated with microcephaly and hydrocephaly. We obtained informed consent from the couple. The patient exploded with a female fetus weighing 700 g, her cranial perimeter at 18 cm and thoracic perimeter at 34 cm. A clubfoot was noted on expulsion of the fetus, which is a particular feature of our case. VL - 12 IS - 6 ER -
Department of Gynecology-Obstetrics, Regional Hospital of Ziniare, Ouagadougou, Burkina Faso
Department of Gynecology-Obstetrics, Joseph KI ZERBO University, Ouagadougou, Burkina Faso
Department of Medecine, Regional Hospital of Ziniare, Ouagadougou, Burkina Faso
Department of Ophthalmology, Regional Hospital of Ziniare, Ouagadougou, Burkina Faso
Department of Gynecology-Obstetrics, Regional Hospital of Fada N’Gourma, Ouagadougou, Burkina Faso
Department of Gynecology-Obstetrics, Sanou Sourou University hospital, Bobo Dioulasso, Burkina Faso
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