Ameliorative Role of <i>Jania Rubens</i> Alga Against Toxicity of Heavy Metal Polluted Water in Male Rats

Soha Mohamed Hamdy; Amany Mohamed Shaban; Yasmeen Saeid Abdel Aziz; Atef Mohamed Mahmoud; Leqaa Abdel Aziz Moemen; Wael Mohamed Ibrahim; Nahed Shafik Gad

doi:doi:10.11648/j.stpp.20180202.13

Ameliorative Role of Jania Rubens Alga Against Toxicity of Heavy Metal Polluted Water in Male Rats

Soha Mohamed Hamdy, Amany Mohamed Shaban, Yasmeen Saeid Abdel Aziz, Atef Mohamed Mahmoud, Leqaa Abdel Aziz Moemen, Wael Mohamed Ibrahim, Nahed Shafik Gad

Published in Science, Technology & Public Policy (Volume 2, Issue 2)

Received: 17 November 2018 Accepted: 4 December 2018 Published: 3 January 2019

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Abstract

Elimination of heavy metals from contaminated water is a significant issue. Algae can be used as the detoxifying agent of these metals. This study was achieved to assess the efficacy of red marine alga (Jania Rubens) opposed to the initial modifications that may be concerning the toxicity of heavy metal-polluted water on male rats. 45 male Wistar rats were separated into 3 groups (15 rat/ group): Group I (control); Group II (Heavy metal group) and Group III (Treated group). There were significant increases in the levels of SGPT, SGOT, ALP, creatinine, urea, UA, malondialdehyde (MDA), glutathione peroxidase (GPx), protein carbonyl (PC) and significant decrease of body weights& levels of blood hemoglobin, total protein, albumin, catalase, SOD, and GSH in the heavy metal group in comparison with control. Meanwhile, the administration of treated water to rats restores all parameters to normal level in the treated group. Highly significant increase in Metallothionein (MT) levels in hepatic and renal tissue of heavy metal group compared to control, that restored to normal in the treated group. Also, Ni, Cd and Pb metals accumulated in liver, kidney and brain tissues were measured in all studied groups. Our results suggested the ameliorative effect of red marine algae treated water opposed to the toxicity of heavy metals in liver, kidney and brain tissues.

Published in	Science, Technology & Public Policy (Volume 2, Issue 2)
DOI	10.11648/j.stpp.20180202.13
Page(s)	38-46
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2019. Published by Science Publishing Group

Keywords

Heavy Metals, Water Treatment, Red Marine Algae, Metallothionein, Oxidative Stress

References

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Soha Mohamed Hamdy, Amany Mohamed Shaban, Yasmeen Saeid Abdel Aziz, Atef Mohamed Mahmoud, Leqaa Abdel Aziz Moemen, et al. (2019). Ameliorative Role of Jania Rubens Alga Against Toxicity of Heavy Metal Polluted Water in Male Rats. Science, Technology & Public Policy, 2(2), 38-46. https://doi.org/10.11648/j.stpp.20180202.13

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ACS Style

Soha Mohamed Hamdy; Amany Mohamed Shaban; Yasmeen Saeid Abdel Aziz; Atef Mohamed Mahmoud; Leqaa Abdel Aziz Moemen, et al. Ameliorative Role of Jania Rubens Alga Against Toxicity of Heavy Metal Polluted Water in Male Rats. Sci. Technol. Public Policy 2019, 2(2), 38-46. doi: 10.11648/j.stpp.20180202.13

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AMA Style

Soha Mohamed Hamdy, Amany Mohamed Shaban, Yasmeen Saeid Abdel Aziz, Atef Mohamed Mahmoud, Leqaa Abdel Aziz Moemen, et al. Ameliorative Role of Jania Rubens Alga Against Toxicity of Heavy Metal Polluted Water in Male Rats. Sci Technol Public Policy. 2019;2(2):38-46. doi: 10.11648/j.stpp.20180202.13

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@article{10.11648/j.stpp.20180202.13,
  author = {Soha Mohamed Hamdy and Amany Mohamed Shaban and Yasmeen Saeid Abdel Aziz and Atef Mohamed Mahmoud and Leqaa Abdel Aziz Moemen and Wael Mohamed Ibrahim and Nahed Shafik Gad},
  title = {Ameliorative Role of Jania Rubens Alga Against Toxicity of Heavy Metal Polluted Water in Male Rats},
  journal = {Science, Technology & Public Policy},
  volume = {2},
  number = {2},
  pages = {38-46},
  doi = {10.11648/j.stpp.20180202.13},
  url = {https://doi.org/10.11648/j.stpp.20180202.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.stpp.20180202.13},
  abstract = {Elimination of heavy metals from contaminated water is a significant issue. Algae can be used as the detoxifying agent of these metals. This study was achieved to assess the efficacy of red marine alga (Jania Rubens) opposed to the initial modifications that may be concerning the toxicity of heavy metal-polluted water on male rats. 45 male Wistar rats were separated into 3 groups (15 rat/ group): Group I (control); Group II (Heavy metal group) and Group III (Treated group). There were significant increases in the levels of SGPT, SGOT, ALP, creatinine, urea, UA, malondialdehyde (MDA), glutathione peroxidase (GPx), protein carbonyl (PC) and significant decrease of body weights& levels of blood hemoglobin, total protein, albumin, catalase, SOD, and GSH in the heavy metal group in comparison with control. Meanwhile, the administration of treated water to rats restores all parameters to normal level in the treated group. Highly significant increase in Metallothionein (MT) levels in hepatic and renal tissue of heavy metal group compared to control, that restored to normal in the treated group. Also, Ni, Cd and Pb metals accumulated in liver, kidney and brain tissues were measured in all studied groups. Our results suggested the ameliorative effect of red marine algae treated water opposed to the toxicity of heavy metals in liver, kidney and brain tissues.},
 year = {2019}
}

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TY  - JOUR
T1  - Ameliorative Role of Jania Rubens Alga Against Toxicity of Heavy Metal Polluted Water in Male Rats
AU  - Soha Mohamed Hamdy
AU  - Amany Mohamed Shaban
AU  - Yasmeen Saeid Abdel Aziz
AU  - Atef Mohamed Mahmoud
AU  - Leqaa Abdel Aziz Moemen
AU  - Wael Mohamed Ibrahim
AU  - Nahed Shafik Gad
Y1  - 2019/01/03
PY  - 2019
N1  - https://doi.org/10.11648/j.stpp.20180202.13
DO  - 10.11648/j.stpp.20180202.13
T2  - Science, Technology & Public Policy
JF  - Science, Technology & Public Policy
JO  - Science, Technology & Public Policy
SP  - 38
EP  - 46
PB  - Science Publishing Group
SN  - 2640-4621
UR  - https://doi.org/10.11648/j.stpp.20180202.13
AB  - Elimination of heavy metals from contaminated water is a significant issue. Algae can be used as the detoxifying agent of these metals. This study was achieved to assess the efficacy of red marine alga (Jania Rubens) opposed to the initial modifications that may be concerning the toxicity of heavy metal-polluted water on male rats. 45 male Wistar rats were separated into 3 groups (15 rat/ group): Group I (control); Group II (Heavy metal group) and Group III (Treated group). There were significant increases in the levels of SGPT, SGOT, ALP, creatinine, urea, UA, malondialdehyde (MDA), glutathione peroxidase (GPx), protein carbonyl (PC) and significant decrease of body weights& levels of blood hemoglobin, total protein, albumin, catalase, SOD, and GSH in the heavy metal group in comparison with control. Meanwhile, the administration of treated water to rats restores all parameters to normal level in the treated group. Highly significant increase in Metallothionein (MT) levels in hepatic and renal tissue of heavy metal group compared to control, that restored to normal in the treated group. Also, Ni, Cd and Pb metals accumulated in liver, kidney and brain tissues were measured in all studied groups. Our results suggested the ameliorative effect of red marine algae treated water opposed to the toxicity of heavy metals in liver, kidney and brain tissues.
VL  - 2
IS  - 2
ER  -

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Author Information

Soha Mohamed Hamdy

Chemistry Department, Faculty of Science, Fayoum University, El- Fayoum, Egypt
Amany Mohamed Shaban

Chemistry Department, Faculty of Science, Fayoum University, El- Fayoum, Egypt
Yasmeen Saeid Abdel Aziz

Pollution Department, National Institute of Oceanography and Fisheries, Cairo, Egypt
Atef Mohamed Mahmoud

Medical Biochemistry Department, Research Institute of Ophthalmology, Cairo, Egypt
Leqaa Abdel Aziz Moemen

Medical Biochemistry Department, Research Institute of Ophthalmology, Cairo, Egypt
Wael Mohamed Ibrahim

Botany Department, Faculty of Science, Damanhour University, Beheira, Egypt
Nahed Shafik Gad

Pollution Department, National Institute of Oceanography and Fisheries, Cairo, Egypt

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Soha Mohamed Hamdy, Amany Mohamed Shaban, Yasmeen Saeid Abdel Aziz, Atef Mohamed Mahmoud, Leqaa Abdel Aziz Moemen, et al. (2019). Ameliorative Role of Jania Rubens Alga Against Toxicity of Heavy Metal Polluted Water in Male Rats. Science, Technology & Public Policy, 2(2), 38-46. https://doi.org/10.11648/j.stpp.20180202.13

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Soha Mohamed Hamdy; Amany Mohamed Shaban; Yasmeen Saeid Abdel Aziz; Atef Mohamed Mahmoud; Leqaa Abdel Aziz Moemen, et al. Ameliorative Role of Jania Rubens Alga Against Toxicity of Heavy Metal Polluted Water in Male Rats. Sci. Technol. Public Policy 2019, 2(2), 38-46. doi: 10.11648/j.stpp.20180202.13

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AMA Style

Soha Mohamed Hamdy, Amany Mohamed Shaban, Yasmeen Saeid Abdel Aziz, Atef Mohamed Mahmoud, Leqaa Abdel Aziz Moemen, et al. Ameliorative Role of Jania Rubens Alga Against Toxicity of Heavy Metal Polluted Water in Male Rats. Sci Technol Public Policy. 2019;2(2):38-46. doi: 10.11648/j.stpp.20180202.13

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@article{10.11648/j.stpp.20180202.13,
  author = {Soha Mohamed Hamdy and Amany Mohamed Shaban and Yasmeen Saeid Abdel Aziz and Atef Mohamed Mahmoud and Leqaa Abdel Aziz Moemen and Wael Mohamed Ibrahim and Nahed Shafik Gad},
  title = {Ameliorative Role of Jania Rubens Alga Against Toxicity of Heavy Metal Polluted Water in Male Rats},
  journal = {Science, Technology & Public Policy},
  volume = {2},
  number = {2},
  pages = {38-46},
  doi = {10.11648/j.stpp.20180202.13},
  url = {https://doi.org/10.11648/j.stpp.20180202.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.stpp.20180202.13},
  abstract = {Elimination of heavy metals from contaminated water is a significant issue. Algae can be used as the detoxifying agent of these metals. This study was achieved to assess the efficacy of red marine alga (Jania Rubens) opposed to the initial modifications that may be concerning the toxicity of heavy metal-polluted water on male rats. 45 male Wistar rats were separated into 3 groups (15 rat/ group): Group I (control); Group II (Heavy metal group) and Group III (Treated group). There were significant increases in the levels of SGPT, SGOT, ALP, creatinine, urea, UA, malondialdehyde (MDA), glutathione peroxidase (GPx), protein carbonyl (PC) and significant decrease of body weights& levels of blood hemoglobin, total protein, albumin, catalase, SOD, and GSH in the heavy metal group in comparison with control. Meanwhile, the administration of treated water to rats restores all parameters to normal level in the treated group. Highly significant increase in Metallothionein (MT) levels in hepatic and renal tissue of heavy metal group compared to control, that restored to normal in the treated group. Also, Ni, Cd and Pb metals accumulated in liver, kidney and brain tissues were measured in all studied groups. Our results suggested the ameliorative effect of red marine algae treated water opposed to the toxicity of heavy metals in liver, kidney and brain tissues.},
 year = {2019}
}

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TY  - JOUR
T1  - Ameliorative Role of Jania Rubens Alga Against Toxicity of Heavy Metal Polluted Water in Male Rats
AU  - Soha Mohamed Hamdy
AU  - Amany Mohamed Shaban
AU  - Yasmeen Saeid Abdel Aziz
AU  - Atef Mohamed Mahmoud
AU  - Leqaa Abdel Aziz Moemen
AU  - Wael Mohamed Ibrahim
AU  - Nahed Shafik Gad
Y1  - 2019/01/03
PY  - 2019
N1  - https://doi.org/10.11648/j.stpp.20180202.13
DO  - 10.11648/j.stpp.20180202.13
T2  - Science, Technology & Public Policy
JF  - Science, Technology & Public Policy
JO  - Science, Technology & Public Policy
SP  - 38
EP  - 46
PB  - Science Publishing Group
SN  - 2640-4621
UR  - https://doi.org/10.11648/j.stpp.20180202.13
AB  - Elimination of heavy metals from contaminated water is a significant issue. Algae can be used as the detoxifying agent of these metals. This study was achieved to assess the efficacy of red marine alga (Jania Rubens) opposed to the initial modifications that may be concerning the toxicity of heavy metal-polluted water on male rats. 45 male Wistar rats were separated into 3 groups (15 rat/ group): Group I (control); Group II (Heavy metal group) and Group III (Treated group). There were significant increases in the levels of SGPT, SGOT, ALP, creatinine, urea, UA, malondialdehyde (MDA), glutathione peroxidase (GPx), protein carbonyl (PC) and significant decrease of body weights& levels of blood hemoglobin, total protein, albumin, catalase, SOD, and GSH in the heavy metal group in comparison with control. Meanwhile, the administration of treated water to rats restores all parameters to normal level in the treated group. Highly significant increase in Metallothionein (MT) levels in hepatic and renal tissue of heavy metal group compared to control, that restored to normal in the treated group. Also, Ni, Cd and Pb metals accumulated in liver, kidney and brain tissues were measured in all studied groups. Our results suggested the ameliorative effect of red marine algae treated water opposed to the toxicity of heavy metals in liver, kidney and brain tissues.
VL  - 2
IS  - 2
ER  -

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