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Biostimulation of Knee Cartilage Using Autologous Micro-Grafts: A Preliminary Study of the Rigenera Protocol in Osteochondral Lesions of the Knee
Agustín Dorta Fernández,
Ana Baroni Luengo
Issue:
Volume 3, Issue 1, March 2018
Pages:
8-12
Received:
26 September 2017
Accepted:
23 January 2018
Published:
23 January 2018
Abstract: Osteochondral pathologies are associated with cartilage loss. Autologous micro-grafts, obtained from various tissues containing mesenchymal stem cells, has proven regenerative properties in various tissues. The study included patients with osteochondral pathology not responding to conventional therapies and considered suitable for treatment with autologous micro-graft. Fifteen days before the intervention, patients started treatment with chondroitin sulfate and supplementary vitamin C and zinc. Autologous micro-grafts were obtained from ear skin and cartilage, disaggregated using the Rigenera system, and injected into the knee under local anesthesia. After the intervention, patients underwent six-week rehabilitation program based on non-weight bearing exercises. Nine patients were enrolled into the study. The autologous graft transfer was successful in all patients, and no severe complications were recorded, including aesthetical defects in the donor site. Eight patients (88.9%) experienced an improvement in all subdomains of the WOMAC scale. The median (IR) improvement in the WOMAC scale was 22.0 (10.0 – 40.0) points. The MRI examination revealed the absence of space-occupying lesions in the knee and the surrounding soft tissues in all patients. An edema reduction was observed in 8 of 9 patients (88.9%); 3 patients (33.3%) showed a thickening of the cartilage line. Autologous micro-graft transfer using the Rigenera system is safe and has promising results in the treatment of chondral injuries associated with pain and function limiting.
Abstract: Osteochondral pathologies are associated with cartilage loss. Autologous micro-grafts, obtained from various tissues containing mesenchymal stem cells, has proven regenerative properties in various tissues. The study included patients with osteochondral pathology not responding to conventional therapies and considered suitable for treatment with au...
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Joint Functional Screening (JFS): Movement for Optimal Health and Body Function: Perspective Clinical Examination
Issue:
Volume 3, Issue 1, March 2018
Pages:
13-16
Received:
9 January 2018
Accepted:
25 January 2018
Published:
12 February 2018
Abstract: Background: Body’s locomotor system, at any given age, need to be pain-free, agile, stable and energetic, symmetrical in joint functional system and muscle power. Joint Functional Screening (JFS) is a musculo-skeletal profiling program via a systematic clinical examination with clinical reasoning of the entire human joints’ functional system, with or without causative limitation to derive a holistic analysis to give a health provider, the strength, flexibility, and stability indicators of the musculoskeletal system. Objective: The purpose of this study was to introduce a feasible and an affordable clinical examination package as Joint Functional Screening. Method: This package including clinical tools to analysis and screen all body joints which can determine muscular imbalances and body abnormalities. Conclusion: JFS is an innovation program to profile a normal musculoskeletal state to decode any underlying anomalies of the body, in an otherwise normal subject, who might be preparing to take up any sporty or gym activities in one’s lifespan that could elicit or uproot an injury which could be otherwise prevented.
Abstract: Background: Body’s locomotor system, at any given age, need to be pain-free, agile, stable and energetic, symmetrical in joint functional system and muscle power. Joint Functional Screening (JFS) is a musculo-skeletal profiling program via a systematic clinical examination with clinical reasoning of the entire human joints’ functional system, with ...
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Critical Appraisal on Randomized Factorial Trial of Falls Prevention Among Older People Living in Their Own Homes
Nadia Mahmoud Ali Abuzied
Issue:
Volume 3, Issue 1, March 2018
Pages:
17-22
Received:
12 November 2017
Accepted:
2 January 2018
Published:
23 February 2018
Abstract: Objective To test the effectiveness of, and explore interactions between, three interventions to prevent falls among older people. Design a randomized controlled trial with a full factorial design. Setting Urban community in Melbourne, Australia. Participants1090 aged 70 years and over and living at home. Most were Australian born and rated their health as good to excellent; just over half lived alone. Interventions Three interventions (group based exercise, home hazard management, and vision improvement) delivered to eight groups defined by the presence or absence of each intervention. Main outcome measure Time to first fall ascertained by an 18 month falls calendar and analyzed with survival analysis techniques. Changes to targeted risk factors were assessed by using measures of quadriceps strength, balance, vision, and number of hazards in the home. Results the rate ratio for exercise was 0.82 (95% confidence interval 0.70 to 0.97, P=0.02), and a significant effect (P < 0.05) was observed for the combinations of interventions that involved exercise. Balance measures improved significantly among the exercise group. Neither home hazard management nor treatment of poor vision showed a significant effect. The strongest effect was observed for all three interventions combined (rate ratio 0.67 (0.51 to 0.88, P=0.004)), producing an estimated 14.0% reduction in the annual fall rate. The number of people needed to be treated to prevent one fall a year ranged from 32 for home hazard management to 7 for all three interventions combined. Conclusions group based exercise was the most potent single intervention tested, and the reduction in falls among this group seems to have been associated with improved balance. Falls were further reduced by the addition of home hazard management or reduce division management, or both of these. Cost effectiveness is yet to be examined. These findings are most applicable to Australian born adults aged 70-84 years living at home who rate their health as good.
Abstract: Objective To test the effectiveness of, and explore interactions between, three interventions to prevent falls among older people. Design a randomized controlled trial with a full factorial design. Setting Urban community in Melbourne, Australia. Participants1090 aged 70 years and over and living at home. Most were Australian born and rated their h...
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Evaluation of Environmental Health Knowledge and Practice Among Youth Football Players in Benghazi, Libya
Isam Denna,
Mohamed H.,
Gawili H.,
Bumakthtra A.,
Buihjar S.,
Salem M.,
Alhassi S.,
Ahmed A.,
Gasibat Q.
Issue:
Volume 3, Issue 1, March 2018
Pages:
23-27
Received:
7 February 2018
Accepted:
25 February 2018
Published:
24 March 2018
Abstract: Environmental health issues and practices are important in sport to reduce the risk of diseases occurrence and transmission. However, there is lack of a data about them among football players in Libya. This study aims to assess the environmental health knowledge and practices among youth football players in Benghazi, Libya. The study involves 182 participants who were involved from five youth football clubs with age means (17 ± 1.3ys). Players filled self-prepared questionnaire, which contained two sections: environmental knowledge and practices. The collected data was analyzed using SPSS. Almost 62% of the participants had not attend any lecture about environmental health. Markedly, 58% of players sharing their tools with others; in particular towels and water bottles. 75% of the sample were non-familiar with the hazards of sharing tools and 65% did not know about blood-born infections and their transmission mode. 81% of participants did not receive vaccinations, and 125 did not receive any acclimation programs about playing in changed temperature environment. In this study, there was a lake of knowledge about essential environmental health issues as well as poor practices regarding to sharing tools, vaccinations and acclimation practices. Hence, establishment of environmental health education programs among footballer players is of great significant.
Abstract: Environmental health issues and practices are important in sport to reduce the risk of diseases occurrence and transmission. However, there is lack of a data about them among football players in Libya. This study aims to assess the environmental health knowledge and practices among youth football players in Benghazi, Libya. The study involves 182 p...
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