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The Importance of the Acute and Subacute Interdisciplinary Management of a Patient with Conus Medullaris Syndrome: Case Report
Salim Torres Yamil Yasser,
Linares Mora Ricardo Andrés,
Sánchez Parra Pedro Santiago,
Campo Álvarez Jessica Paola
Issue:
Volume 8, Issue 3, June 2022
Pages:
33-37
Received:
16 December 2021
Accepted:
6 January 2022
Published:
10 May 2022
Abstract: Background: One of the main components in spinal cord injury´s management lies in the early and adequate interventions, as well as the possible outcomes considering the time from the trauma to every step afterwards. This case reports the course of action taken in an adult previously healthy that was diagnosed with conus medullaris syndrome because of falling from a considerable height. Intraoperative Monitoring can help us to look after the early changes that may occur in surgical correction and allows giving prognostic value to neurophysiological changes that will affect the patient's quality of life. Diagnostic images are also essential for a proper surgical approach, and an adequate follow-up of the patient. All these tools facilitate the rehabilitation treatment, in whom our final objective will be to achieve the best global functionality. Objective: Based on a case, we seek to describe the importance of the acute and subacute interdisciplinary management of a patient with Conus Medullaris Syndrome. Methods: Case report, the information was extracted from the medical history. Results: The result was positive due to the fast and adequate response given from a first level health center to the operation room and the rehabilitation phase. Conclusion: An adequate interdisciplinary conduct approaches each individual with specific and realistic objectives, with continuous assessments and always considering the possible progressions and/or variations of the patient’s state. Explaining the complications inherent to the surgical and non-surgical component, for an optimal result according to the conditions and resources available.
Abstract: Background: One of the main components in spinal cord injury´s management lies in the early and adequate interventions, as well as the possible outcomes considering the time from the trauma to every step afterwards. This case reports the course of action taken in an adult previously healthy that was diagnosed with conus medullaris syndrome because ...
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Frequency of Allo-Immunization in Sickle Cell Disease: Case of the Patients at the Laquintinie Hospital in Douala-Cameroon
Celianthe Guegang Guegang,
Romaric De Manfouo Tuono,
Simon Ngamli Fewou,
Lazare Kaptue
Issue:
Volume 8, Issue 3, June 2022
Pages:
38-43
Received:
7 April 2022
Accepted:
21 April 2022
Published:
10 May 2022
Abstract: Background: Allo-immunization is an immune response to foreign antigens after exposure to genetically different cells or tissues. Allo-immunized patients with sickle cell disease (SCD) appear to experience worse survival compared to non allo-immunized patients. Therefore, to contribute to the management of patients living with SCD and improve the blood transfusion process, we aimed to determine the frequency of allo-immunization in SCD’s patients. To realize this study, we carry out a cross sectional study in one Hospital of Douala-Cameroon. Method: Plasma was prepared from collected blood sample, electrophoresis was done and depending on the migration on the gel; the type of electrophoresis was determine. Blood group ABO/Rh was done. After electrophoresis, depending on the result obtained those that was not homozygote (SS) and heterozygote sickle cell anemia (AS) was discarded. The check for irregular agglutinins was done using the indirect Coombs test. Clinical and biological characteristics of the different participants were studied and analyzed using a Statview statistical software. Result: We obtained 104 sickle cell patient, out of these we had 55% of positive RAI, with an average transfusion of 7.35. Also 83 patients were homozygote sickle cell anemia for a mean age of 15.75 years old (ranging from 1 to 52 years). The result obtained shows that the number of blood transfusion for homozygote sickle cell patient increases with age and that homozygote sickle cell patient received more blood transfusion than heterozygote patient. It can also be said that allo-immunization in these patients originate from the multiple blood transfusion received that were not fully compatible and that it affects more children (from 1 – 15), they accounted for about 53.85% of the total population. Our result obtained implies that in the future, sickle cell patient will have difficulty in finding compatible blood for treatment and is a real problem since transfusion is the major standard of care for patient suffering from sickle cell anemia in Cameroon. The absence of treatment may lead to the death of the patient. To help reduced allo-immunization, extended compatibility test in all the red blood cell system and routinely screening for the presence of irregulars agglutinins may reduce the frequency of allo-immunization.
Abstract: Background: Allo-immunization is an immune response to foreign antigens after exposure to genetically different cells or tissues. Allo-immunized patients with sickle cell disease (SCD) appear to experience worse survival compared to non allo-immunized patients. Therefore, to contribute to the management of patients living with SCD and improve the b...
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Estimation of COVID-19 Prevalence in a Tertiary Care Hospital in Bangladesh & Impact of COVID-19 Vaccine
Aklima Akter,
Md. Arifur Rahman,
Md. Zakiur Rahman,
Mirtyunjoy Acharjee,
Farjana Sultana,
Saurab Kishore Munshi
Issue:
Volume 8, Issue 3, June 2022
Pages:
44-48
Received:
21 May 2022
Accepted:
6 June 2022
Published:
16 June 2022
Abstract: The corona virus disease-2019 (COVID-19), also known as the corona pandemic, is an ongoing public health emergency caused by coronavirus 2019 (COVID-19), which is spread by the transmission of coronavirus-2, which causes severe acute respiratory syndrome. The first incidence of COVID-19 in Bangladesh was reported on March 7, 2020. There were 450,273,828 diagnoses worldwide as of March 9, 2022, with 1,948,471 in Bangladesh. To better understand the current state of COVID-19 in Brahmanbaria, a retrospective study was done at Brahmanbaria Medical College with COVID-19-suspected patients. Methods: A total of 600 oropharyngeal and nasopharyngeal swab samples were taken from COVID-19 suspected person, as well as the appropriate proceedings were identified using a reverse transcriptase–polymerase chain reaction assay. We found 193 (32%) of positive cases that represent similarity with national. Among 193 positive cases which 127 (66%) was male that is greater amount from female. Out of 193 positive cases 114 were symptomatic that is 59% and 79 were asymptomatic which is 41%. Asymptomatic infection is more frightening because it is difficult to identify patients. And Odds ratio is 0.9, it indicates a protective effect of vaccination against COVID-19. That reduced risk is 1-odds so will be 10 percent reduced risk of exposure.
Abstract: The corona virus disease-2019 (COVID-19), also known as the corona pandemic, is an ongoing public health emergency caused by coronavirus 2019 (COVID-19), which is spread by the transmission of coronavirus-2, which causes severe acute respiratory syndrome. The first incidence of COVID-19 in Bangladesh was reported on March 7, 2020. There were 450,27...
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Interleukin-6 ELISA in the Early Diagnosis of Neonatal Sepsis: Feasibility Within a Poor Setting in Bafoussam, Cameroon
Palmer Masumbe Netongo,
Marie Christine Magne Nzuno,
Severin Donald Kamdem,
Desire Keptcheu,
Armel Herve Nwabo Kamdje,
Irene Ane Anyangwe
Issue:
Volume 8, Issue 3, June 2022
Pages:
49-54
Received:
23 May 2022
Accepted:
20 June 2022
Published:
30 June 2022
Abstract: Introduction: Neonatal sepsis is a leading cause of mortality in Cameroon. Diagnosis still relies heavily on the detection of C reactive protein (CRP) levels, whereas other biomarkers like interleukin 6 (IL-6), could improve the early diagnosis of neonatal sepsis in comparison to CRP. This study aimed to assess the efficacy and feasibility of IL-6 ELISA as an early diagnostic tool within a Cameroonian context with the hope of its applicability in other poor income settings and in other diseases like COVID-19. Methods: We enrolled thirty-two (32) neonates equally distributed between a septic group (including infants with risk factors and clinical signs of sepsis) and a control group (infants without clinical signs of infections) in the study. We performed Full Blood Count, C-reactive protein and IL-6 ELISA on all blood samples. Thirty-five (35) medical personnel were interviewed in order to assess acceptability, practicality (cost and duration) and a limited-efficacy of IL-6 ELISA testing at the Bafoussam regional Hospital, Cameroon. Results: The mean age of participants was 2.81 days. IL-6 ELSIA showed a sensitivity, specificity, positive predictive value and negative predictive value of 56.20%, 100%, 100% and 69.56% respectively while CRP was reported to be highly specific (81.25%). Despite a longer testing time of IL-6 ELISA compared to CRP (p = 0.0385), the IL-6 was acceptable (p = 0.008), affordable (p = 0.006) and could be promising for use within this poor setting. Conclusion: Though we did not see a strong correlation between its levels and the apparition of disease, IL-6 ELISA testing was feasible as a highly specific marker for an early diagnosis neonatal sepsis in Bafoussam, and could acceptably be used as an early diagnostic marker for other diseases like COVID-19 within that context.
Abstract: Introduction: Neonatal sepsis is a leading cause of mortality in Cameroon. Diagnosis still relies heavily on the detection of C reactive protein (CRP) levels, whereas other biomarkers like interleukin 6 (IL-6), could improve the early diagnosis of neonatal sepsis in comparison to CRP. This study aimed to assess the efficacy and feasibility of IL-6 ...
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