Cantrell Syndrome – A Rare Complex Congenital Anomaly: A Case Report and Literature Review

B. Ennadif; N. Marzouki; F. Alaoui Inboui; S. Salimi; B. Slaoui; Elkorchi; K. Chbani

doi:doi:10.11648/ajp.20241001.13

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Cantrell Syndrome – A Rare Complex Congenital Anomaly: A Case Report and Literature Review

B. Ennadif^*, N. Marzouki, F. Alaoui Inboui, S. Salimi, B. Slaoui, Elkorchi, K. Chbani

Published in American Journal of Pediatrics (Volume 10, Issue 1)

Received: 10 January 2024 Accepted: 29 January 2024 Published: 5 February 2024

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Abstract

Cantrell’s pentalogy is a rare and complex white line congenital anomaly, it is first described by Cantrell et al. in 1958. It affects 5.5 children per 1,000,000 live births worldwide. The full spectrum of this syndrome includes five anomalies: an anterior diaphragm defect, a medial supraumbilical abdominal wall defect, a diaphragmatic pericardium defect, a lower sternum defect with intracardiac anomalies. The complete form that associates the five malformations of the Cantrell pentalogy is less common than the incomplete form. The embryogenesis of Cantrell's pentalogy can be caused by a problem in isolation of the frontal mesoderm around 14-18 days of gravidity; The etiopathogenesis of this pattern isn't yet fully understood, numerous factors can be indicted. The prognosis depends on the complexity of the cardiac malformation. We report the case of a 3 month old infant with a complete Cantrell pentalogy and complex congenital hear desease as this is the first case that has been reported in Morocco. And we highlight through our work the importance of prenatal diagnosis for early care. This case highlights the value of gestation monitoring and antenatal comforting and perfecting the quality of complaint operation services during the first days of life.

Published in	American Journal of Pediatrics (Volume 10, Issue 1)
DOI	10.11648/ajp.20241001.13
Page(s)	13-17
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Congenital Heart Disease, Thoracoabdominal Wall Defect, Ectopia Cordis, Complete Form, Pentalogy of Cantrell

References

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APA Style

Ennadif, B., Marzouki, N., Inboui, F. A., Salimi, S., Slaoui, B., et al. (2024). Cantrell Syndrome – A Rare Complex Congenital Anomaly: A Case Report and Literature Review. American Journal of Pediatrics, 10(1), 13-17. https://doi.org/10.11648/ajp.20241001.13

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ACS Style

Ennadif, B.; Marzouki, N.; Inboui, F. A.; Salimi, S.; Slaoui, B., et al. Cantrell Syndrome – A Rare Complex Congenital Anomaly: A Case Report and Literature Review. Am. J. Pediatr. 2024, 10(1), 13-17. doi: 10.11648/ajp.20241001.13

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AMA Style

Ennadif B, Marzouki N, Inboui FA, Salimi S, Slaoui B, et al. Cantrell Syndrome – A Rare Complex Congenital Anomaly: A Case Report and Literature Review. Am J Pediatr. 2024;10(1):13-17. doi: 10.11648/ajp.20241001.13

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@article{10.11648/ajp.20241001.13,
  author = {B. Ennadif and N. Marzouki and F. Alaoui Inboui and S. Salimi and B. Slaoui and Elkorchi and K. Chbani},
  title = {Cantrell Syndrome – A Rare Complex Congenital Anomaly: A Case Report and Literature Review},
  journal = {American Journal of Pediatrics},
  volume = {10},
  number = {1},
  pages = {13-17},
  doi = {10.11648/ajp.20241001.13},
  url = {https://doi.org/10.11648/ajp.20241001.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.ajp.20241001.13},
  abstract = {Cantrell’s pentalogy is a rare and complex white line congenital anomaly, it is first described by Cantrell et al. in 1958. It affects 5.5 children per 1,000,000 live births worldwide. The full spectrum of this syndrome includes five anomalies: an anterior diaphragm defect, a medial supraumbilical abdominal wall defect, a diaphragmatic pericardium defect, a lower sternum defect with intracardiac anomalies. The complete form that associates the five malformations of the Cantrell pentalogy is less common than the incomplete form. The embryogenesis of Cantrell's pentalogy can be caused by a problem in isolation of the frontal mesoderm around 14-18 days of gravidity; The etiopathogenesis of this pattern isn't yet fully understood, numerous factors can be indicted. The prognosis depends on the complexity of the cardiac malformation. We report the case of a 3 month old infant with a complete Cantrell pentalogy and complex congenital hear desease as this is the first case that has been reported in Morocco. And we highlight through our work the importance of prenatal diagnosis for early care. This case highlights the value of gestation monitoring and antenatal comforting and perfecting the quality of complaint operation services during the first days of life.
},
 year = {2024}
}

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TY - JOUR
T1 - Cantrell Syndrome – A Rare Complex Congenital Anomaly: A Case Report and Literature Review
AU - B. Ennadif
AU - N. Marzouki
AU - F. Alaoui Inboui
AU - S. Salimi
AU - B. Slaoui
AU - Elkorchi
AU - K. Chbani
Y1 - 2024/02/05
PY - 2024
N1 - https://doi.org/10.11648/ajp.20241001.13
DO - 10.11648/ajp.20241001.13
T2 - American Journal of Pediatrics
JF - American Journal of Pediatrics
JO - American Journal of Pediatrics
SP - 13
EP - 17
PB - Science Publishing Group
SN - 2472-0909
UR - https://doi.org/10.11648/ajp.20241001.13
AB - Cantrell’s pentalogy is a rare and complex white line congenital anomaly, it is first described by Cantrell et al. in 1958. It affects 5.5 children per 1,000,000 live births worldwide. The full spectrum of this syndrome includes five anomalies: an anterior diaphragm defect, a medial supraumbilical abdominal wall defect, a diaphragmatic pericardium defect, a lower sternum defect with intracardiac anomalies. The complete form that associates the five malformations of the Cantrell pentalogy is less common than the incomplete form. The embryogenesis of Cantrell's pentalogy can be caused by a problem in isolation of the frontal mesoderm around 14-18 days of gravidity; The etiopathogenesis of this pattern isn't yet fully understood, numerous factors can be indicted. The prognosis depends on the complexity of the cardiac malformation. We report the case of a 3 month old infant with a complete Cantrell pentalogy and complex congenital hear desease as this is the first case that has been reported in Morocco. And we highlight through our work the importance of prenatal diagnosis for early care. This case highlights the value of gestation monitoring and antenatal comforting and perfecting the quality of complaint operation services during the first days of life.

VL - 10
IS - 1
ER -

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Author Information

B. Ennadif

Pediatrics II Department, A. Harouchi Children’s Hospital, IBN ROCHD University Hospital Center, Faculty of Medicine, Hassan II University Casablanca, Casablanca, Morocco

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N. Marzouki

Pediatrics II Department, A. Harouchi Children’s Hospital, IBN ROCHD University Hospital Center, Faculty of Medicine, Hassan II University Casablanca, Casablanca, Morocco
F. Alaoui Inboui

Pediatrics II Department, A. Harouchi Children’s Hospital, IBN ROCHD University Hospital Center, Faculty of Medicine, Hassan II University Casablanca, Casablanca, Morocco
S. Salimi

Pediatrics II Department, A. Harouchi Children’s Hospital, IBN ROCHD University Hospital Center, Faculty of Medicine, Hassan II University Casablanca, Casablanca, Morocco
B. Slaoui

Pediatrics II Department, A. Harouchi Children’s Hospital, IBN ROCHD University Hospital Center, Faculty of Medicine, Hassan II University Casablanca, Casablanca, Morocco
Elkorchi

Radiology Department, A. Harouchi Children’s Hospital, IBN ROCHD University Hospital Center, Faculty of Medicine, Hassan II University Casablanca, Casablanca, Morocco
K. Chbani

Radiology Department, A. Harouchi Children’s Hospital, IBN ROCHD University Hospital Center, Faculty of Medicine, Hassan II University Casablanca, Casablanca, Morocco

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APA Style

Ennadif, B., Marzouki, N., Inboui, F. A., Salimi, S., Slaoui, B., et al. (2024). Cantrell Syndrome – A Rare Complex Congenital Anomaly: A Case Report and Literature Review. American Journal of Pediatrics, 10(1), 13-17. https://doi.org/10.11648/ajp.20241001.13

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ACS Style

Ennadif, B.; Marzouki, N.; Inboui, F. A.; Salimi, S.; Slaoui, B., et al. Cantrell Syndrome – A Rare Complex Congenital Anomaly: A Case Report and Literature Review. Am. J. Pediatr. 2024, 10(1), 13-17. doi: 10.11648/ajp.20241001.13

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AMA Style

Ennadif B, Marzouki N, Inboui FA, Salimi S, Slaoui B, et al. Cantrell Syndrome – A Rare Complex Congenital Anomaly: A Case Report and Literature Review. Am J Pediatr. 2024;10(1):13-17. doi: 10.11648/ajp.20241001.13

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@article{10.11648/ajp.20241001.13,
  author = {B. Ennadif and N. Marzouki and F. Alaoui Inboui and S. Salimi and B. Slaoui and Elkorchi and K. Chbani},
  title = {Cantrell Syndrome – A Rare Complex Congenital Anomaly: A Case Report and Literature Review},
  journal = {American Journal of Pediatrics},
  volume = {10},
  number = {1},
  pages = {13-17},
  doi = {10.11648/ajp.20241001.13},
  url = {https://doi.org/10.11648/ajp.20241001.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.ajp.20241001.13},
  abstract = {Cantrell’s pentalogy is a rare and complex white line congenital anomaly, it is first described by Cantrell et al. in 1958. It affects 5.5 children per 1,000,000 live births worldwide. The full spectrum of this syndrome includes five anomalies: an anterior diaphragm defect, a medial supraumbilical abdominal wall defect, a diaphragmatic pericardium defect, a lower sternum defect with intracardiac anomalies. The complete form that associates the five malformations of the Cantrell pentalogy is less common than the incomplete form. The embryogenesis of Cantrell's pentalogy can be caused by a problem in isolation of the frontal mesoderm around 14-18 days of gravidity; The etiopathogenesis of this pattern isn't yet fully understood, numerous factors can be indicted. The prognosis depends on the complexity of the cardiac malformation. We report the case of a 3 month old infant with a complete Cantrell pentalogy and complex congenital hear desease as this is the first case that has been reported in Morocco. And we highlight through our work the importance of prenatal diagnosis for early care. This case highlights the value of gestation monitoring and antenatal comforting and perfecting the quality of complaint operation services during the first days of life.
},
 year = {2024}
}

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VL - 10
IS - 1
ER -

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