This publication treated the determination (qualitative) and the quantification (quantitative) of the steroidal and flavonoids constituent molecules in the Strychnos spinosa pips. These molecules were extracted by esterification between the Strychnos spinosa pips and citric acid molecules in a reflux assembly such as the evaluated total moles of the substance’s organic functions, deduced by bibliographies values, and which could reacted with the citric acid molecules was in excess. Thus, the weight ratio between the Strychnos spinosa pips and citric acid was equal to 7.39. Seeing that the reflux assembly could be assimilated as a closed reactor composed with a beaker-250ml, the observed speed constant ksee was equal to 4.3168×10-2 [L2×mol-2×mn-1]. Thereafter, the transesterification of the Strychnos spinosa citric acid esters solution by methanol was carried out with the volume ratio 2.82 and the extraction with dichloromethane followed by hplc-analysis permitted to determine the presence of virtuous steroidal and flavonoid molecules in the Strychnos spinosa pips respectively 4.25×10-1 [gsteroïds per gStrychnos spinosa pips] and 3.89×10-1 [gflavonoids per gStrychnos spinosa pips]. The constituent molecules majority in the Strychnos spinosa pips were betulinic acid and eriocitrin which vertues as antioxidant, anti-inflammatory and anti-cancer were shown in bibliographies. Thus, it was important the perspective to valorize the Strychnos spinosa pips.
| Published in | American Journal of Applied Chemistry (Volume 11, Issue 1) |
| DOI | 10.11648/j.ajac.20231101.13 |
| Page(s) | 21-32 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2023. Published by Science Publishing Group |
Strychnos spinosa Pips, Betulinic Acid, Steroids, Eriocitrin, Neoeriocitrin, Flavonoids, Citric Acid, Esterification
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APA Style
Andry Tahina Rabeharitsara, Rakotonanahary Lovasoa Carolia Sabrinah, Hanitra Marie Ratsimba, Nambinina Richard Randriana, Baholy Robijaona, et al. (2023). Determining of the Constituent Molecules in the Strychnos spinosa Pips by Extraction with Citric Acid Esterification Procedure. American Journal of Applied Chemistry, 11(1), 21-32. https://doi.org/10.11648/j.ajac.20231101.13
ACS Style
Andry Tahina Rabeharitsara; Rakotonanahary Lovasoa Carolia Sabrinah; Hanitra Marie Ratsimba; Nambinina Richard Randriana; Baholy Robijaona, et al. Determining of the Constituent Molecules in the Strychnos spinosa Pips by Extraction with Citric Acid Esterification Procedure. Am. J. Appl. Chem. 2023, 11(1), 21-32. doi: 10.11648/j.ajac.20231101.13
AMA Style
Andry Tahina Rabeharitsara, Rakotonanahary Lovasoa Carolia Sabrinah, Hanitra Marie Ratsimba, Nambinina Richard Randriana, Baholy Robijaona, et al. Determining of the Constituent Molecules in the Strychnos spinosa Pips by Extraction with Citric Acid Esterification Procedure. Am J Appl Chem. 2023;11(1):21-32. doi: 10.11648/j.ajac.20231101.13
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Download@article{10.11648/j.ajac.20231101.13,
author = {Andry Tahina Rabeharitsara and Rakotonanahary Lovasoa Carolia Sabrinah and Hanitra Marie Ratsimba and Nambinina Richard Randriana and Baholy Robijaona and Rakotomamonjy Pierre},
title = {Determining of the Constituent Molecules in the Strychnos spinosa Pips by Extraction with Citric Acid Esterification Procedure},
journal = {American Journal of Applied Chemistry},
volume = {11},
number = {1},
pages = {21-32},
doi = {10.11648/j.ajac.20231101.13},
url = {https://doi.org/10.11648/j.ajac.20231101.13},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajac.20231101.13},
abstract = {This publication treated the determination (qualitative) and the quantification (quantitative) of the steroidal and flavonoids constituent molecules in the Strychnos spinosa pips. These molecules were extracted by esterification between the Strychnos spinosa pips and citric acid molecules in a reflux assembly such as the evaluated total moles of the substance’s organic functions, deduced by bibliographies values, and which could reacted with the citric acid molecules was in excess. Thus, the weight ratio between the Strychnos spinosa pips and citric acid was equal to 7.39. Seeing that the reflux assembly could be assimilated as a closed reactor composed with a beaker-250ml, the observed speed constant ksee was equal to 4.3168×10-2 [L2×mol-2×mn-1]. Thereafter, the transesterification of the Strychnos spinosa citric acid esters solution by methanol was carried out with the volume ratio 2.82 and the extraction with dichloromethane followed by hplc-analysis permitted to determine the presence of virtuous steroidal and flavonoid molecules in the Strychnos spinosa pips respectively 4.25×10-1 [gsteroïds per gStrychnos spinosa pips] and 3.89×10-1 [gflavonoids per gStrychnos spinosa pips]. The constituent molecules majority in the Strychnos spinosa pips were betulinic acid and eriocitrin which vertues as antioxidant, anti-inflammatory and anti-cancer were shown in bibliographies. Thus, it was important the perspective to valorize the Strychnos spinosa pips.},
year = {2023}
}
TY - JOUR T1 - Determining of the Constituent Molecules in the Strychnos spinosa Pips by Extraction with Citric Acid Esterification Procedure AU - Andry Tahina Rabeharitsara AU - Rakotonanahary Lovasoa Carolia Sabrinah AU - Hanitra Marie Ratsimba AU - Nambinina Richard Randriana AU - Baholy Robijaona AU - Rakotomamonjy Pierre Y1 - 2023/02/24 PY - 2023 N1 - https://doi.org/10.11648/j.ajac.20231101.13 DO - 10.11648/j.ajac.20231101.13 T2 - American Journal of Applied Chemistry JF - American Journal of Applied Chemistry JO - American Journal of Applied Chemistry SP - 21 EP - 32 PB - Science Publishing Group SN - 2330-8745 UR - https://doi.org/10.11648/j.ajac.20231101.13 AB - This publication treated the determination (qualitative) and the quantification (quantitative) of the steroidal and flavonoids constituent molecules in the Strychnos spinosa pips. These molecules were extracted by esterification between the Strychnos spinosa pips and citric acid molecules in a reflux assembly such as the evaluated total moles of the substance’s organic functions, deduced by bibliographies values, and which could reacted with the citric acid molecules was in excess. Thus, the weight ratio between the Strychnos spinosa pips and citric acid was equal to 7.39. Seeing that the reflux assembly could be assimilated as a closed reactor composed with a beaker-250ml, the observed speed constant ksee was equal to 4.3168×10-2 [L2×mol-2×mn-1]. Thereafter, the transesterification of the Strychnos spinosa citric acid esters solution by methanol was carried out with the volume ratio 2.82 and the extraction with dichloromethane followed by hplc-analysis permitted to determine the presence of virtuous steroidal and flavonoid molecules in the Strychnos spinosa pips respectively 4.25×10-1 [gsteroïds per gStrychnos spinosa pips] and 3.89×10-1 [gflavonoids per gStrychnos spinosa pips]. The constituent molecules majority in the Strychnos spinosa pips were betulinic acid and eriocitrin which vertues as antioxidant, anti-inflammatory and anti-cancer were shown in bibliographies. Thus, it was important the perspective to valorize the Strychnos spinosa pips. VL - 11 IS - 1 ER -
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