Introduction: Respiratory distress syndrome (RDS) previously known as hyaline membrane disease (HMD), is one of the most common respiratory disorders in preterm neonates, appearing in the first few hours or immediately after delivery. The lack of pulmonary surfactant caused by immaturity of the lung is the etiology of RDS. Risk factors of RDS include maternal (sociodemographic and obstetric abnormalities), intrapartum and fetal factors. Objectives: To know the risk factors of RDS in preterm neonates at Prof. DR. I. G. N. G. Ngoerah Hopital Denpasar, Bali. Methods: This study was a retrospective study with design of case control study that conducted from January 2021 until February 2022. Samples of this study is neonates born prematurely with diagnosed of RDS at Prof. DR. I. G. N. G. Ngoerah Hopital during this study periode. All the data were analyzed by SPSS version 25. Result: The total sample of this study was 170 subjects, consisting of 85 subjects with RDS and 85 subjects as control. Multivariate analysis with logistic regression showed that gestational age < 34 weeks (OR 4.6; 95% CI 1.882-11.346; p = 0.001), APGAR score < 7 (OR 2.7; 95% CI 1.216-6.295; p = 0.015) and maternal preeclampsia (OR 3.58; 95% CI 1.09-11.75; p = 0.03) were statistically significant as the risk factors of RDS. Conclusion: Respiratory Distress Syndrome still occurs often in preterm newborns younger than 34 weeks of gestation. The incidence of RDS in preterm newborns was significantly increased by gestational age less than 34 weeks, APGAR score less than 7, and maternal preeclampsia. In particular, prospective cohort studies with bigger, more focused sample sizes are required in order to generate more accurate study.
| Published in | American Journal of Pediatrics (Volume 8, Issue 4) |
| DOI | 10.11648/j.ajp.20220804.15 |
| Page(s) | 218-224 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2022. Published by Science Publishing Group |
Respiratory Distress Syndrome, Risk Factor, Preterm Neonates
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APA Style
Maria Angela Yustina Fernandez, I Made Sukmawati, I Made Kardana, I Wayan Dharma Artana, Putu Junara Putra, et al. (2022). Risk Factors of Respiratory Distress Syndrome in Premature Infants at Prof Dr. I. G. N. G Ngoerah Hospital, Denpasar, Bali. American Journal of Pediatrics, 8(4), 218-224. https://doi.org/10.11648/j.ajp.20220804.15
ACS Style
Maria Angela Yustina Fernandez; I Made Sukmawati; I Made Kardana; I Wayan Dharma Artana; Putu Junara Putra, et al. Risk Factors of Respiratory Distress Syndrome in Premature Infants at Prof Dr. I. G. N. G Ngoerah Hospital, Denpasar, Bali. Am. J. Pediatr. 2022, 8(4), 218-224. doi: 10.11648/j.ajp.20220804.15
AMA Style
Maria Angela Yustina Fernandez, I Made Sukmawati, I Made Kardana, I Wayan Dharma Artana, Putu Junara Putra, et al. Risk Factors of Respiratory Distress Syndrome in Premature Infants at Prof Dr. I. G. N. G Ngoerah Hospital, Denpasar, Bali. Am J Pediatr. 2022;8(4):218-224. doi: 10.11648/j.ajp.20220804.15
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Download@article{10.11648/j.ajp.20220804.15,
author = {Maria Angela Yustina Fernandez and I Made Sukmawati and I Made Kardana and I Wayan Dharma Artana and Putu Junara Putra and Putu Mas Vina Paramitha Cempaka},
title = {Risk Factors of Respiratory Distress Syndrome in Premature Infants at Prof Dr. I. G. N. G Ngoerah Hospital, Denpasar, Bali},
journal = {American Journal of Pediatrics},
volume = {8},
number = {4},
pages = {218-224},
doi = {10.11648/j.ajp.20220804.15},
url = {https://doi.org/10.11648/j.ajp.20220804.15},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajp.20220804.15},
abstract = {Introduction: Respiratory distress syndrome (RDS) previously known as hyaline membrane disease (HMD), is one of the most common respiratory disorders in preterm neonates, appearing in the first few hours or immediately after delivery. The lack of pulmonary surfactant caused by immaturity of the lung is the etiology of RDS. Risk factors of RDS include maternal (sociodemographic and obstetric abnormalities), intrapartum and fetal factors. Objectives: To know the risk factors of RDS in preterm neonates at Prof. DR. I. G. N. G. Ngoerah Hopital Denpasar, Bali. Methods: This study was a retrospective study with design of case control study that conducted from January 2021 until February 2022. Samples of this study is neonates born prematurely with diagnosed of RDS at Prof. DR. I. G. N. G. Ngoerah Hopital during this study periode. All the data were analyzed by SPSS version 25. Result: The total sample of this study was 170 subjects, consisting of 85 subjects with RDS and 85 subjects as control. Multivariate analysis with logistic regression showed that gestational age Conclusion: Respiratory Distress Syndrome still occurs often in preterm newborns younger than 34 weeks of gestation. The incidence of RDS in preterm newborns was significantly increased by gestational age less than 34 weeks, APGAR score less than 7, and maternal preeclampsia. In particular, prospective cohort studies with bigger, more focused sample sizes are required in order to generate more accurate study.},
year = {2022}
}
TY - JOUR T1 - Risk Factors of Respiratory Distress Syndrome in Premature Infants at Prof Dr. I. G. N. G Ngoerah Hospital, Denpasar, Bali AU - Maria Angela Yustina Fernandez AU - I Made Sukmawati AU - I Made Kardana AU - I Wayan Dharma Artana AU - Putu Junara Putra AU - Putu Mas Vina Paramitha Cempaka Y1 - 2022/10/18 PY - 2022 N1 - https://doi.org/10.11648/j.ajp.20220804.15 DO - 10.11648/j.ajp.20220804.15 T2 - American Journal of Pediatrics JF - American Journal of Pediatrics JO - American Journal of Pediatrics SP - 218 EP - 224 PB - Science Publishing Group SN - 2472-0909 UR - https://doi.org/10.11648/j.ajp.20220804.15 AB - Introduction: Respiratory distress syndrome (RDS) previously known as hyaline membrane disease (HMD), is one of the most common respiratory disorders in preterm neonates, appearing in the first few hours or immediately after delivery. The lack of pulmonary surfactant caused by immaturity of the lung is the etiology of RDS. Risk factors of RDS include maternal (sociodemographic and obstetric abnormalities), intrapartum and fetal factors. Objectives: To know the risk factors of RDS in preterm neonates at Prof. DR. I. G. N. G. Ngoerah Hopital Denpasar, Bali. Methods: This study was a retrospective study with design of case control study that conducted from January 2021 until February 2022. Samples of this study is neonates born prematurely with diagnosed of RDS at Prof. DR. I. G. N. G. Ngoerah Hopital during this study periode. All the data were analyzed by SPSS version 25. Result: The total sample of this study was 170 subjects, consisting of 85 subjects with RDS and 85 subjects as control. Multivariate analysis with logistic regression showed that gestational age Conclusion: Respiratory Distress Syndrome still occurs often in preterm newborns younger than 34 weeks of gestation. The incidence of RDS in preterm newborns was significantly increased by gestational age less than 34 weeks, APGAR score less than 7, and maternal preeclampsia. In particular, prospective cohort studies with bigger, more focused sample sizes are required in order to generate more accurate study. VL - 8 IS - 4 ER -
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