LncRNAs: The Ideal Composer of the Melody for Life

Qingyu Cheng; Shengwei Ke; A. R. Ghanam; Xiaoyuan Song

doi:doi:10.11648/j.bs.20160202.11

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LncRNAs: The Ideal Composer of the Melody for Life

Qingyu Cheng, Shengwei Ke, A. R. Ghanam, Xiaoyuan Song

Published in Biomedical Sciences (Volume 2, Issue 2)

Received: 18 May 2016 Accepted: 6 June 2016 Published: 30 June 2016

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Abstract

Long noncoding RNAs (lncNRAs), as major transcripts from the genome, are becoming indispensable keys to invisible doors linking to a new horizon, prompting a shift in the previous thoughts that lncRNAs are the transcriptional noises and by-products. The most puzzling fact, however, is that in spite of their pervasive regulation of many biological processes and diverse human diseases, their exact functions are still unclear. Here we review the regulations by lncRNAs at different levels, revealing some insights upon the molecular mechanisms and pathogenesis of related diseases.

Published in	Biomedical Sciences (Volume 2, Issue 2)
DOI	10.11648/j.bs.20160202.11
Page(s)	11-15
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2016. Published by Science Publishing Group

Keywords

Long Noncoding RNA, Human Diseases, Epigenetic, Transcription, Post-Transcription

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APA Style

Qingyu Cheng, Shengwei Ke, A. R. Ghanam, Xiaoyuan Song. (2016). LncRNAs: The Ideal Composer of the Melody for Life. Biomedical Sciences, 2(2), 11-15. https://doi.org/10.11648/j.bs.20160202.11

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ACS Style

Qingyu Cheng; Shengwei Ke; A. R. Ghanam; Xiaoyuan Song. LncRNAs: The Ideal Composer of the Melody for Life. Biomed. Sci. 2016, 2(2), 11-15. doi: 10.11648/j.bs.20160202.11

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AMA Style

Qingyu Cheng, Shengwei Ke, A. R. Ghanam, Xiaoyuan Song. LncRNAs: The Ideal Composer of the Melody for Life. Biomed Sci. 2016;2(2):11-15. doi: 10.11648/j.bs.20160202.11

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@article{10.11648/j.bs.20160202.11,
  author = {Qingyu Cheng and Shengwei Ke and A. R. Ghanam and Xiaoyuan Song},
  title = {LncRNAs: The Ideal Composer of the Melody for Life},
  journal = {Biomedical Sciences},
  volume = {2},
  number = {2},
  pages = {11-15},
  doi = {10.11648/j.bs.20160202.11},
  url = {https://doi.org/10.11648/j.bs.20160202.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.bs.20160202.11},
  abstract = {Long noncoding RNAs (lncNRAs), as major transcripts from the genome, are becoming indispensable keys to invisible doors linking to a new horizon, prompting a shift in the previous thoughts that lncRNAs are the transcriptional noises and by-products. The most puzzling fact, however, is that in spite of their pervasive regulation of many biological processes and diverse human diseases, their exact functions are still unclear. Here we review the regulations by lncRNAs at different levels, revealing some insights upon the molecular mechanisms and pathogenesis of related diseases.},
 year = {2016}
}

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TY  - JOUR
T1  - LncRNAs: The Ideal Composer of the Melody for Life
AU  - Qingyu Cheng
AU  - Shengwei Ke
AU  - A. R. Ghanam
AU  - Xiaoyuan Song
Y1  - 2016/06/30
PY  - 2016
N1  - https://doi.org/10.11648/j.bs.20160202.11
DO  - 10.11648/j.bs.20160202.11
T2  - Biomedical Sciences
JF  - Biomedical Sciences
JO  - Biomedical Sciences
SP  - 11
EP  - 15
PB  - Science Publishing Group
SN  - 2575-3932
UR  - https://doi.org/10.11648/j.bs.20160202.11
AB  - Long noncoding RNAs (lncNRAs), as major transcripts from the genome, are becoming indispensable keys to invisible doors linking to a new horizon, prompting a shift in the previous thoughts that lncRNAs are the transcriptional noises and by-products. The most puzzling fact, however, is that in spite of their pervasive regulation of many biological processes and diverse human diseases, their exact functions are still unclear. Here we review the regulations by lncRNAs at different levels, revealing some insights upon the molecular mechanisms and pathogenesis of related diseases.
VL  - 2
IS  - 2
ER  -

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Author Information

Qingyu Cheng

CAS Key Laboratory of Brain Function and Disease, CAS Center for Excellence in Molecular Cell Science, School of Life Sciences, University of Science and Technology of China, Hefei, China
Shengwei Ke

CAS Key Laboratory of Brain Function and Disease, CAS Center for Excellence in Molecular Cell Science, School of Life Sciences, University of Science and Technology of China, Hefei, China
A. R. Ghanam

CAS Key Laboratory of Brain Function and Disease, CAS Center for Excellence in Molecular Cell Science, School of Life Sciences, University of Science and Technology of China, Hefei, China
Xiaoyuan Song

CAS Key Laboratory of Brain Function and Disease, CAS Center for Excellence in Molecular Cell Science, School of Life Sciences, University of Science and Technology of China, Hefei, China

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APA Style

Qingyu Cheng, Shengwei Ke, A. R. Ghanam, Xiaoyuan Song. (2016). LncRNAs: The Ideal Composer of the Melody for Life. Biomedical Sciences, 2(2), 11-15. https://doi.org/10.11648/j.bs.20160202.11

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ACS Style

Qingyu Cheng; Shengwei Ke; A. R. Ghanam; Xiaoyuan Song. LncRNAs: The Ideal Composer of the Melody for Life. Biomed. Sci. 2016, 2(2), 11-15. doi: 10.11648/j.bs.20160202.11

Copy | Download

AMA Style

Qingyu Cheng, Shengwei Ke, A. R. Ghanam, Xiaoyuan Song. LncRNAs: The Ideal Composer of the Melody for Life. Biomed Sci. 2016;2(2):11-15. doi: 10.11648/j.bs.20160202.11

Copy | Download

@article{10.11648/j.bs.20160202.11,
  author = {Qingyu Cheng and Shengwei Ke and A. R. Ghanam and Xiaoyuan Song},
  title = {LncRNAs: The Ideal Composer of the Melody for Life},
  journal = {Biomedical Sciences},
  volume = {2},
  number = {2},
  pages = {11-15},
  doi = {10.11648/j.bs.20160202.11},
  url = {https://doi.org/10.11648/j.bs.20160202.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.bs.20160202.11},
  abstract = {Long noncoding RNAs (lncNRAs), as major transcripts from the genome, are becoming indispensable keys to invisible doors linking to a new horizon, prompting a shift in the previous thoughts that lncRNAs are the transcriptional noises and by-products. The most puzzling fact, however, is that in spite of their pervasive regulation of many biological processes and diverse human diseases, their exact functions are still unclear. Here we review the regulations by lncRNAs at different levels, revealing some insights upon the molecular mechanisms and pathogenesis of related diseases.},
 year = {2016}
}

Copy | Download

TY  - JOUR
T1  - LncRNAs: The Ideal Composer of the Melody for Life
AU  - Qingyu Cheng
AU  - Shengwei Ke
AU  - A. R. Ghanam
AU  - Xiaoyuan Song
Y1  - 2016/06/30
PY  - 2016
N1  - https://doi.org/10.11648/j.bs.20160202.11
DO  - 10.11648/j.bs.20160202.11
T2  - Biomedical Sciences
JF  - Biomedical Sciences
JO  - Biomedical Sciences
SP  - 11
EP  - 15
PB  - Science Publishing Group
SN  - 2575-3932
UR  - https://doi.org/10.11648/j.bs.20160202.11
AB  - Long noncoding RNAs (lncNRAs), as major transcripts from the genome, are becoming indispensable keys to invisible doors linking to a new horizon, prompting a shift in the previous thoughts that lncRNAs are the transcriptional noises and by-products. The most puzzling fact, however, is that in spite of their pervasive regulation of many biological processes and diverse human diseases, their exact functions are still unclear. Here we review the regulations by lncRNAs at different levels, revealing some insights upon the molecular mechanisms and pathogenesis of related diseases.
VL  - 2
IS  - 2
ER  -

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