LncRNAs: The Ideal Composer of the Melody for Life
Qingyu Cheng,
Shengwei Ke,
A. R. Ghanam,
Xiaoyuan Song
Issue:
Volume 2, Issue 2, March 2016
Pages:
11-15
Received:
18 May 2016
Accepted:
6 June 2016
Published:
30 June 2016
DOI:
10.11648/j.bs.20160202.11
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Abstract: Long noncoding RNAs (lncNRAs), as major transcripts from the genome, are becoming indispensable keys to invisible doors linking to a new horizon, prompting a shift in the previous thoughts that lncRNAs are the transcriptional noises and by-products. The most puzzling fact, however, is that in spite of their pervasive regulation of many biological processes and diverse human diseases, their exact functions are still unclear. Here we review the regulations by lncRNAs at different levels, revealing some insights upon the molecular mechanisms and pathogenesis of related diseases.
Abstract: Long noncoding RNAs (lncNRAs), as major transcripts from the genome, are becoming indispensable keys to invisible doors linking to a new horizon, prompting a shift in the previous thoughts that lncRNAs are the transcriptional noises and by-products. The most puzzling fact, however, is that in spite of their pervasive regulation of many biological p...
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