An Impact of Energy of Consciousness (The Trivedi Effect®) on the Physicochemical, Thermal, Structural, and Behavioral Properties of Magnesium Gluconate
Mahendra Kumar Trivedi,
Alice Branton,
Dahryn Trivedi,
Gopal Nayak,
Ariadne Esmene Afaganis,
Barbara Marie Bader,
Brian A. Weekes,
Daphne Luisa Dumas,
Denise Marie Fiedler,
Dennille Mellesia Smith,
Desi Pano,
Donna Felice Galla,
Donna Maria Alija,
Elaine Barbara Mullins,
Elaine M. Scorza,
Ellia O'Donnell,
Fabio Massimo Paciucci,
Frances Goodman Warlick,
Haddon Norman Salt,
Inthirani Arul,
Jacqueline Y. Andrews,
James Jay McLeran,
James Stephen Burnett,
Jean Caroline White,
Parthasarathi Panda,
Kalyan Kumar Sethi,
Snehasis Jana
Issue:
Volume 3, Issue 2, March 2017
Pages:
42-54
Received:
6 February 2017
Accepted:
22 February 2017
Published:
14 March 2017
Abstract: Magnesium gluconate is a potent antioxidant used for the prevention and treatment of hypomagnesia. The current research was aimed to investigate the impact of The Trivedi Effect® - Energy of Consciousness Healing Treatment (Biofield Energy Healing Treatment) on magnesium gluconate for the change in the physicochemical, structural, thermal and behavioral properties using PXRD, PSD, FT-IR, UV-vis spectroscopy, TGA, and DSC analysis. Magnesium gluconate was divided into two parts – one part was control, while another part was treated with The Trivedi Effect® - Energy of Consciousness Healing Treatment (Biofield Energy Healing Treatment) remotely by twenty renowned Biofield Energy Healers and defined as The Trivedi Effect® treated sample. The PXRD analysis exhibited that the crystallite size of the treated sample was remarkably changed from range -37.52% to 180.14% compared with the control sample. The average crystallite size was reduced in the treated sample by 0.11% compared with the control sample. PSD analysis revealed that the particle sizes in the treated sample at d10 and d50 values were significantly decreased by 11.36% and 8.25%, respectively, while the particle size at d90 was increased in the treated sample by 2.43% compared with the control sample. The treated sample’s surface area was significantly increased by 9.54% compared with the control sample. The FT-IR and UV-vis analysis showed that the structure of the magnesium gluconate remained the same in both the treated and control samples. The TGA analysis revealed the four steps thermal degradation of the both samples and the total weight loss of the treated sample was reduced by 2.32% compared with the control sample. This result indicated that the thermal stability of the treated sample was improved compared with the control sample. The DSC analysis revealed that the melting temperature of the treated sample (171.05°C) was decreased by 0.17% compared with the control sample (171.34°C). The latent heat of fusion was decreased by 1.16% in the treated sample compared with the control sample. The current study infers that The Trivedi Effect® - Energy of Consciousness Healing Treatment (Biofield Energy Healing Treatment) might lead to a new polymorphic form of magnesium gluconate, which would be more soluble, bioavailable, and thermally stable compared with the untreated compound. Hence, The Trivedi Effect® Treated magnesium gluconate would be very useful to design better nutraceutical and/or pharmaceutical formulations that might offer better therapeutic responses against inflammatory diseases, immunological disorders, stress, aging and other chronic infections.
Abstract: Magnesium gluconate is a potent antioxidant used for the prevention and treatment of hypomagnesia. The current research was aimed to investigate the impact of The Trivedi Effect® - Energy of Consciousness Healing Treatment (Biofield Energy Healing Treatment) on magnesium gluconate for the change in the physicochemical, structural, thermal and behav...
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Novel BCL6 Inhibitor (FX1): Advances in Diffuse Large B-Cell Lymphomas (DLBCLs) Treatment
Issue:
Volume 3, Issue 2, March 2017
Pages:
55-57
Received:
25 November 2016
Accepted:
13 February 2017
Published:
26 April 2017
Abstract: Diffuse large B-cell lymphomas (DLBCLs) are the most common and aggressive type of all the lymphomas. B cell lymphoma 6 (BCL6) oncogene is highly expressed in DLBCLs and one of the major reasons of treatment failure. Recent findings suggest that specific BCL6 inhibitor (FX1) disrupted formation of the BCL6 repression complex, reactivated BCL6 target genes, that in-turn suppressed growth of DLBCLs cells, primary human DLBCLs specimens, as well as induced regression of established tumors in mice derived from DLBCLs cells.
Abstract: Diffuse large B-cell lymphomas (DLBCLs) are the most common and aggressive type of all the lymphomas. B cell lymphoma 6 (BCL6) oncogene is highly expressed in DLBCLs and one of the major reasons of treatment failure. Recent findings suggest that specific BCL6 inhibitor (FX1) disrupted formation of the BCL6 repression complex, reactivated BCL6 targe...
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