To further enhance the carboxymethyl chitosan (collectively, carboxymethyl chitosan, CMCS) water-soluble and effect of coagulation and hemostatic, O-carboxymethyl chitosan (O-CMCS) and N,O-carboxymethyl chitosan (CMCS) are prepared by carboxymethyl chitosan modification under alkaline conditions, then Folic Acid-O-carboxymethyl chitosan (FA-O-CMCS) and Ca-nanocarboxymethyl chitosan(Ca-nmCMCS) are prepared by compounding folic acid and Ca2+, respectively. The samples are characterized by Infrared spectrum(IR), X-ray diffraction(XRD) and scanning electron microscope (SEM), and compared with each other, with the results showing as follows: FA-O-CMCS and Ca-nmCMCS are successfully synthesized respectively. Comparison of the two results shows that Ca-nmCMCS is more stable, and has smaller and more uniform particle size about 27.4 nm, better dispersion without adhesion and stronger crystalline structure corresponding to the result of the solubility. But, the coagulation and hemostasis time of FA-O-CMCS is shorter than Ca-nmCMCS, and the former has the better effects of rapid coagulation and hemostasis. This provids a wide range of prospects for the application of Ca-nmCMCS and FA-O-CMCS.
| Published in | International Journal of Biomedical Materials Research (Volume 5, Issue 3) |
| DOI | 10.11648/j.ijbmr.20170503.13 |
| Page(s) | 44-49 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2017. Published by Science Publishing Group |
Carboxymethyl Chitosan, Carboxymethyl Chitosan Complexes, Complex Characterization, Performance
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APA Style
Lidan Dong, Changping Wei, Shuang Sun, Fengming Wang. (2017). Preparation and Property Study of CMCS Complexes. International Journal of Biomedical Materials Research, 5(3), 44-49. https://doi.org/10.11648/j.ijbmr.20170503.13
ACS Style
Lidan Dong; Changping Wei; Shuang Sun; Fengming Wang. Preparation and Property Study of CMCS Complexes. Int. J. Biomed. Mater. Res. 2017, 5(3), 44-49. doi: 10.11648/j.ijbmr.20170503.13
AMA Style
Lidan Dong, Changping Wei, Shuang Sun, Fengming Wang. Preparation and Property Study of CMCS Complexes. Int J Biomed Mater Res. 2017;5(3):44-49. doi: 10.11648/j.ijbmr.20170503.13
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Download@article{10.11648/j.ijbmr.20170503.13,
author = {Lidan Dong and Changping Wei and Shuang Sun and Fengming Wang},
title = {Preparation and Property Study of CMCS Complexes},
journal = {International Journal of Biomedical Materials Research},
volume = {5},
number = {3},
pages = {44-49},
doi = {10.11648/j.ijbmr.20170503.13},
url = {https://doi.org/10.11648/j.ijbmr.20170503.13},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijbmr.20170503.13},
abstract = {To further enhance the carboxymethyl chitosan (collectively, carboxymethyl chitosan, CMCS) water-soluble and effect of coagulation and hemostatic, O-carboxymethyl chitosan (O-CMCS) and N,O-carboxymethyl chitosan (CMCS) are prepared by carboxymethyl chitosan modification under alkaline conditions, then Folic Acid-O-carboxymethyl chitosan (FA-O-CMCS) and Ca-nanocarboxymethyl chitosan(Ca-nmCMCS) are prepared by compounding folic acid and Ca2+, respectively. The samples are characterized by Infrared spectrum(IR), X-ray diffraction(XRD) and scanning electron microscope (SEM), and compared with each other, with the results showing as follows: FA-O-CMCS and Ca-nmCMCS are successfully synthesized respectively. Comparison of the two results shows that Ca-nmCMCS is more stable, and has smaller and more uniform particle size about 27.4 nm, better dispersion without adhesion and stronger crystalline structure corresponding to the result of the solubility. But, the coagulation and hemostasis time of FA-O-CMCS is shorter than Ca-nmCMCS, and the former has the better effects of rapid coagulation and hemostasis. This provids a wide range of prospects for the application of Ca-nmCMCS and FA-O-CMCS.},
year = {2017}
}
TY - JOUR T1 - Preparation and Property Study of CMCS Complexes AU - Lidan Dong AU - Changping Wei AU - Shuang Sun AU - Fengming Wang Y1 - 2017/08/01 PY - 2017 N1 - https://doi.org/10.11648/j.ijbmr.20170503.13 DO - 10.11648/j.ijbmr.20170503.13 T2 - International Journal of Biomedical Materials Research JF - International Journal of Biomedical Materials Research JO - International Journal of Biomedical Materials Research SP - 44 EP - 49 PB - Science Publishing Group SN - 2330-7579 UR - https://doi.org/10.11648/j.ijbmr.20170503.13 AB - To further enhance the carboxymethyl chitosan (collectively, carboxymethyl chitosan, CMCS) water-soluble and effect of coagulation and hemostatic, O-carboxymethyl chitosan (O-CMCS) and N,O-carboxymethyl chitosan (CMCS) are prepared by carboxymethyl chitosan modification under alkaline conditions, then Folic Acid-O-carboxymethyl chitosan (FA-O-CMCS) and Ca-nanocarboxymethyl chitosan(Ca-nmCMCS) are prepared by compounding folic acid and Ca2+, respectively. The samples are characterized by Infrared spectrum(IR), X-ray diffraction(XRD) and scanning electron microscope (SEM), and compared with each other, with the results showing as follows: FA-O-CMCS and Ca-nmCMCS are successfully synthesized respectively. Comparison of the two results shows that Ca-nmCMCS is more stable, and has smaller and more uniform particle size about 27.4 nm, better dispersion without adhesion and stronger crystalline structure corresponding to the result of the solubility. But, the coagulation and hemostasis time of FA-O-CMCS is shorter than Ca-nmCMCS, and the former has the better effects of rapid coagulation and hemostasis. This provids a wide range of prospects for the application of Ca-nmCMCS and FA-O-CMCS. VL - 5 IS - 3 ER -
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