Dynamic Thiol/Disulphide Homeostasis in Patients with Vaginitis

Raziye Desdicioglu; Melahat Yildirim; Betul Ozbek; Gokhan Kılıc; Ozcan Erel; Ayse Filiz Yavuz

doi:doi:10.11648/j.jgo.20180601.11

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Dynamic Thiol/Disulphide Homeostasis in Patients with Vaginitis

Raziye Desdicioglu, Melahat Yildirim, Betul Ozbek, Gokhan Kılıc, Ozcan Erel, Ayse Filiz Yavuz

Published in Journal of Gynecology and Obstetrics (Volume 6, Issue 1)

Received: 5 December 2017 Accepted: 15 December 2017 Published: 16 January 2018

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Abstract

This study investigated the thiol-disulphide balance in vaginitis, which is a local inflammatory condition, through the use of a new method. A cross-sectional study involving 82 women (45 women with vaginitis and 37 women in control group) was conducted at Ataturk Education and Research Hospital, Ankara, Turkey from February 2016 to April 2016. Their ages varied between 19-75 years (mean: 42.8±11.6), were incorporated into the study. Thiol – disulphide parameters were measured and the obtained results were compared. The results showed that the serum disulphide level and disulphide/native thiol ratio in the group with vaginitis (p = 0.03 and p = 0.04) and the native thiol/total thiol ratio in the control group was higher (p = 0.03). In this study, it was shown that serum dynamic thiol-disulphide balance in the women with vaginitis had varied. Although vaginitis is a localized infectious inflammatory condition, the increase in the systemic oxidative stress is important. This study is the first article in the literature that investigates the relationship between dynamic thiol-disulphide balance and vaginitis.

Published in	Journal of Gynecology and Obstetrics (Volume 6, Issue 1)
DOI	10.11648/j.jgo.20180601.11
Page(s)	1-5
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2018. Published by Science Publishing Group

Keywords

Disulphide, Thiol, Vaginitis

References

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APA Style

Raziye Desdicioglu, Melahat Yildirim, Betul Ozbek, Gokhan Kılıc, Ozcan Erel, et al. (2018). Dynamic Thiol/Disulphide Homeostasis in Patients with Vaginitis. Journal of Gynecology and Obstetrics, 6(1), 1-5. https://doi.org/10.11648/j.jgo.20180601.11

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ACS Style

Raziye Desdicioglu; Melahat Yildirim; Betul Ozbek; Gokhan Kılıc; Ozcan Erel, et al. Dynamic Thiol/Disulphide Homeostasis in Patients with Vaginitis. J. Gynecol. Obstet. 2018, 6(1), 1-5. doi: 10.11648/j.jgo.20180601.11

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AMA Style

Raziye Desdicioglu, Melahat Yildirim, Betul Ozbek, Gokhan Kılıc, Ozcan Erel, et al. Dynamic Thiol/Disulphide Homeostasis in Patients with Vaginitis. J Gynecol Obstet. 2018;6(1):1-5. doi: 10.11648/j.jgo.20180601.11

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@article{10.11648/j.jgo.20180601.11,
  author = {Raziye Desdicioglu and Melahat Yildirim and Betul Ozbek and Gokhan Kılıc and Ozcan Erel and Ayse Filiz Yavuz},
  title = {Dynamic Thiol/Disulphide Homeostasis in Patients with Vaginitis},
  journal = {Journal of Gynecology and Obstetrics},
  volume = {6},
  number = {1},
  pages = {1-5},
  doi = {10.11648/j.jgo.20180601.11},
  url = {https://doi.org/10.11648/j.jgo.20180601.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jgo.20180601.11},
  abstract = {This study investigated the thiol-disulphide balance in vaginitis, which is a local inflammatory condition, through the use of a new method. A cross-sectional study involving 82 women (45 women with vaginitis and 37 women in control group) was conducted at Ataturk Education and Research Hospital, Ankara, Turkey from February 2016 to April 2016. Their ages varied between 19-75 years (mean: 42.8±11.6), were incorporated into the study. Thiol – disulphide parameters were measured and the obtained results were compared. The results showed that the serum disulphide level and disulphide/native thiol ratio in the group with vaginitis (p = 0.03 and p = 0.04) and the native thiol/total thiol ratio in the control group was higher (p = 0.03). In this study, it was shown that serum dynamic thiol-disulphide balance in the women with vaginitis had varied. Although vaginitis is a localized infectious inflammatory condition, the increase in the systemic oxidative stress is important. This study is the first article in the literature that investigates the relationship between dynamic thiol-disulphide balance and vaginitis.},
 year = {2018}
}

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TY  - JOUR
T1  - Dynamic Thiol/Disulphide Homeostasis in Patients with Vaginitis
AU  - Raziye Desdicioglu
AU  - Melahat Yildirim
AU  - Betul Ozbek
AU  - Gokhan Kılıc
AU  - Ozcan Erel
AU  - Ayse Filiz Yavuz
Y1  - 2018/01/16
PY  - 2018
N1  - https://doi.org/10.11648/j.jgo.20180601.11
DO  - 10.11648/j.jgo.20180601.11
T2  - Journal of Gynecology and Obstetrics
JF  - Journal of Gynecology and Obstetrics
JO  - Journal of Gynecology and Obstetrics
SP  - 1
EP  - 5
PB  - Science Publishing Group
SN  - 2376-7820
UR  - https://doi.org/10.11648/j.jgo.20180601.11
AB  - This study investigated the thiol-disulphide balance in vaginitis, which is a local inflammatory condition, through the use of a new method. A cross-sectional study involving 82 women (45 women with vaginitis and 37 women in control group) was conducted at Ataturk Education and Research Hospital, Ankara, Turkey from February 2016 to April 2016. Their ages varied between 19-75 years (mean: 42.8±11.6), were incorporated into the study. Thiol – disulphide parameters were measured and the obtained results were compared. The results showed that the serum disulphide level and disulphide/native thiol ratio in the group with vaginitis (p = 0.03 and p = 0.04) and the native thiol/total thiol ratio in the control group was higher (p = 0.03). In this study, it was shown that serum dynamic thiol-disulphide balance in the women with vaginitis had varied. Although vaginitis is a localized infectious inflammatory condition, the increase in the systemic oxidative stress is important. This study is the first article in the literature that investigates the relationship between dynamic thiol-disulphide balance and vaginitis.
VL  - 6
IS  - 1
ER  -

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Author Information

Raziye Desdicioglu

Obstetrics and Gynecology Department, Faculty of Medicine, Yildirim Beyazit University, Ankara, Turkey
Melahat Yildirim

Obstetrics and Gynecology Department, Faculty of Medicine, Yildirim Beyazit University, Ankara, Turkey
Betul Ozbek

Biochemistry Department, Faculty of Medicine, Yildirim Beyazit University, Ankara, Turkey
Gokhan Kılıc
Ozcan Erel

Biochemistry Department, Faculty of Medicine, Yildirim Beyazit University, Ankara, Turkey
Ayse Filiz Yavuz

Obstetrics and Gynecology Department, Faculty of Medicine, Yildirim Beyazit University, Ankara, Turkey

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APA Style

Raziye Desdicioglu, Melahat Yildirim, Betul Ozbek, Gokhan Kılıc, Ozcan Erel, et al. (2018). Dynamic Thiol/Disulphide Homeostasis in Patients with Vaginitis. Journal of Gynecology and Obstetrics, 6(1), 1-5. https://doi.org/10.11648/j.jgo.20180601.11

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ACS Style

Raziye Desdicioglu; Melahat Yildirim; Betul Ozbek; Gokhan Kılıc; Ozcan Erel, et al. Dynamic Thiol/Disulphide Homeostasis in Patients with Vaginitis. J. Gynecol. Obstet. 2018, 6(1), 1-5. doi: 10.11648/j.jgo.20180601.11

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AMA Style

Raziye Desdicioglu, Melahat Yildirim, Betul Ozbek, Gokhan Kılıc, Ozcan Erel, et al. Dynamic Thiol/Disulphide Homeostasis in Patients with Vaginitis. J Gynecol Obstet. 2018;6(1):1-5. doi: 10.11648/j.jgo.20180601.11

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@article{10.11648/j.jgo.20180601.11,
  author = {Raziye Desdicioglu and Melahat Yildirim and Betul Ozbek and Gokhan Kılıc and Ozcan Erel and Ayse Filiz Yavuz},
  title = {Dynamic Thiol/Disulphide Homeostasis in Patients with Vaginitis},
  journal = {Journal of Gynecology and Obstetrics},
  volume = {6},
  number = {1},
  pages = {1-5},
  doi = {10.11648/j.jgo.20180601.11},
  url = {https://doi.org/10.11648/j.jgo.20180601.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jgo.20180601.11},
  abstract = {This study investigated the thiol-disulphide balance in vaginitis, which is a local inflammatory condition, through the use of a new method. A cross-sectional study involving 82 women (45 women with vaginitis and 37 women in control group) was conducted at Ataturk Education and Research Hospital, Ankara, Turkey from February 2016 to April 2016. Their ages varied between 19-75 years (mean: 42.8±11.6), were incorporated into the study. Thiol – disulphide parameters were measured and the obtained results were compared. The results showed that the serum disulphide level and disulphide/native thiol ratio in the group with vaginitis (p = 0.03 and p = 0.04) and the native thiol/total thiol ratio in the control group was higher (p = 0.03). In this study, it was shown that serum dynamic thiol-disulphide balance in the women with vaginitis had varied. Although vaginitis is a localized infectious inflammatory condition, the increase in the systemic oxidative stress is important. This study is the first article in the literature that investigates the relationship between dynamic thiol-disulphide balance and vaginitis.},
 year = {2018}
}

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TY  - JOUR
T1  - Dynamic Thiol/Disulphide Homeostasis in Patients with Vaginitis
AU  - Raziye Desdicioglu
AU  - Melahat Yildirim
AU  - Betul Ozbek
AU  - Gokhan Kılıc
AU  - Ozcan Erel
AU  - Ayse Filiz Yavuz
Y1  - 2018/01/16
PY  - 2018
N1  - https://doi.org/10.11648/j.jgo.20180601.11
DO  - 10.11648/j.jgo.20180601.11
T2  - Journal of Gynecology and Obstetrics
JF  - Journal of Gynecology and Obstetrics
JO  - Journal of Gynecology and Obstetrics
SP  - 1
EP  - 5
PB  - Science Publishing Group
SN  - 2376-7820
UR  - https://doi.org/10.11648/j.jgo.20180601.11
AB  - This study investigated the thiol-disulphide balance in vaginitis, which is a local inflammatory condition, through the use of a new method. A cross-sectional study involving 82 women (45 women with vaginitis and 37 women in control group) was conducted at Ataturk Education and Research Hospital, Ankara, Turkey from February 2016 to April 2016. Their ages varied between 19-75 years (mean: 42.8±11.6), were incorporated into the study. Thiol – disulphide parameters were measured and the obtained results were compared. The results showed that the serum disulphide level and disulphide/native thiol ratio in the group with vaginitis (p = 0.03 and p = 0.04) and the native thiol/total thiol ratio in the control group was higher (p = 0.03). In this study, it was shown that serum dynamic thiol-disulphide balance in the women with vaginitis had varied. Although vaginitis is a localized infectious inflammatory condition, the increase in the systemic oxidative stress is important. This study is the first article in the literature that investigates the relationship between dynamic thiol-disulphide balance and vaginitis.
VL  - 6
IS  - 1
ER  -

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