Abstract: Background: Tonsillectomy remains one of the most common surgical procedures performed in the world. Despite advances in anesthetic and surgical techniques, post-tonsillectomy morbidity remains a significant clinical problem. Among them, postoperative bleeding is the most frequent and severe one. Other common short-term complications of tonsillectomy are nausea, vomiting, fever and Pain after tonsillectomy, which been regarded as a major morbidity in the early post-operative period. A prospective study was designed to determine the effect of postoperative antibiotics to reduce or prevent the postoperative complications at, Benghazi medical center . From October 2012 to may 2013 over a period o. Method: the same doctors operated 100 patients of varying ages and both sexes. Patients divided into two groups, (50) patients received postoperative antibiotic (amoxicillin) and (50) patients did not received antibiotics. All patients scheduled to return for a routine follow up appointment one week following surgery and examined for complications. Results: seven (7%) develop post tonsillectomy infection two (2%) using antibiotic and five (5%) were not using antibiotic. Among the infected patients one (1%) had post tonsillectomy bleeding, two (2%) had infection with pus and four (4%) have sever sore throat with dehydration. In infected patients not using antibiotic two (2%) age (3-12) years old and three (3%) age (>12) years old. four (4%) have last attack of tonsillitis less than one month and one (1%) have the last attack more than one month. two (2%) time required to perform the operation less than thirty minutes and three (3%) more than thirty minutes. In infected patients use antibiotic no patients (0%) age (3-12) years old and two (2%) age (>12) years old. One (1%) has last attack of tonsillitis less than one month and one (1%) have the last attack more than one month. No patients (0%) time required to perform the operation less than thirty minutes and two (2%) more than thirty minutes.Abstract: Background: Tonsillectomy remains one of the most common surgical procedures performed in the world. Despite advances in anesthetic and surgical techniques, post-tonsillectomy morbidity remains a significant clinical problem. Among them, postoperative bleeding is the most frequent and severe one. Other common short-term complications of tonsillecto...Show More