International Journal of Immunology

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Volume 5, Issue 4, August 2017

  • Characterization of the Anti-HLA Class I and II IgG Antibodies in Moroccan IVIg Using Regular Beads and Ibeads in Luminex Multiplex Single Antigen Immunoassay

    Fatiha EL Hilali, Vadim Jucaud, Hajar EL Hilali, Mohammed Hassan Bhuiyan, Andrew Mancuso, Nancy LiuSullivan, Abdeslem Elidrissi, Hamid Mazouz

    Issue: Volume 5, Issue 4, August 2017
    Pages: 53-65
    Received: 15 May 2017
    Accepted: 23 May 2017
    Published: 18 July 2017
    DOI: 10.11648/j.iji.20170504.11
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    Abstract: Therapeutic Immunoglobulin Intravenous (IVIg), approved to treat a wide range of autoimmune and primary immunodeficiency diseases, contain mixture of polyreactive and polyclonal IgG purified from the pooled plasma of thousands of donors. The aim of this study is to characterize the profiles of anti- Human Leukocyte Antigen (HLA) class-I and class-I... Show More
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  • CTLA-4, ICOS, PD1 and PTPN22 Gene Polymorphisms and Susceptibility to Autoimmune Hepatitis Type 1

    María Del Pilar Fortes, Paolo Tassinari, Irma Machado

    Issue: Volume 5, Issue 4, August 2017
    Pages: 66-73
    Received: 30 June 2017
    Accepted: 10 July 2017
    Published: 10 August 2017
    DOI: 10.11648/j.iji.20170504.12
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    Abstract: Autoimmune hepatitis type 1 (AIH-1) is a progressive inflammatory liver disorder in which HLA Class II gene polymorphism prevails as the most important genetic risk. However, other gene polymorphisms have been associated with this disease. The single nucleotide polymorphisms of four candidate genes (CTLA-4 +49A/G, ICOS c.1564 T/C, PD1.3 G/A, PTPN22... Show More
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  • The Expression Patterns of Some Pro-inflammatory and Anti-inflammatory Cytokines Genes Pre and Post Acute Exercise

    Ehiaghe Friday Alfred, Onyenekwe Charles Chinedum, Ifeanyichukwu Martins, Akosile Christopher Olusanjo, Ehiaghe Imuetiyan Joy, Nancy Ibeh Chitogu, Ukibe Nkiruka Rose, Osakue Nosa, Ekpe Elijah Chukwuemeka

    Issue: Volume 5, Issue 4, August 2017
    Pages: 74-79
    Received: 3 July 2017
    Accepted: 18 July 2017
    Published: 11 August 2017
    DOI: 10.11648/j.iji.20170504.13
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    Abstract: This study was designed to determine the expression patterns of some pro-inflammatory and anti-inflammatory cytokine genes in some young male undergraduates that passed through exhaustive exercise using the Bruce protocol for sub-maximal acute exercise as studies have shown that exhaustive exercise activates the release of multiple cytokine genes w... Show More
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