-
Comparative Study of Prolactin Levels in Acne and Non-Acne Individuals Among Students of College of Health Sciences, Nnamdi Azikiwe University, Nnewi, Nigeria
Emmanuel Okechukwu Chukwu,
Odunukwe Juliet Ifeoma,
Terkuma Chia,
Ufearo Chibueze Stephen,
Ugbor Godwin Onyedikachi
Issue:
Volume 3, Issue 4, July 2017
Pages:
25-31
Received:
22 February 2017
Accepted:
21 March 2017
Published:
18 October 2017
Abstract: Prolactin (PRL) is well recognized for its role(s) in mammary gland development and function as well as over three hundred non-lactational functions. However, androgens have a main role in acne pathogenesis and the interaction between prolactin and androgens generate the hypothesis of prolactin role in acne pathogenesis. Therefore a difference should exist in the prolactin hormone levels of acne individuals in comparison with non-acne individuals. The aim of this study was to make assessment and comparison of serum hormonal levels of prolactin in acne vulgaris individuals and non-acne individuals. In this cross-sectional case control study, serum levels of prolactin were collected and estimated in 60 subjects consisting of 30 males and 30 females each; of which 15 were the control group and 15, the test group in each category respectively. Also certain criteria’s were looked into such as subject’s age, state of health, menstrual patterns (for females) and much more. Data collected was analyzed using the Software Package for Social Sciences (SPSS). At the end of the experiment, the result showed no significant change (p<0.05), however mean serum prolactin levels were significantly high among the acne cases in both the males (12.26 ± 1.50) when compared to the control of males (8.80 ± 1.03), and also acne cases of the females (22.04 ± 4.59) when compared to the control of the females (12.92 ± 1.62) females. A non-significant change in the comparism of serum prolactin levels of acne subjects and non-acne subjects in both males and females may be as result of the small sample size used. However, more powerful studies are needed. An increase in the mean serum prolactin levels of acne subjects in both categories when compared to non-acne subjects indicates the contribution of prolactin in the pathogenesis of acne.
Abstract: Prolactin (PRL) is well recognized for its role(s) in mammary gland development and function as well as over three hundred non-lactational functions. However, androgens have a main role in acne pathogenesis and the interaction between prolactin and androgens generate the hypothesis of prolactin role in acne pathogenesis. Therefore a difference shou...
Show More
-
Cutaneous and Oral Mucosal Lesions in Cri-du-chat Syndrome
Lilly Esquivel-Pedraza,
Laura Fernández-Cuevas,
María del Pilar Milke-García,
Jesús Antonio Hernández-Morales,
Judith Domínguez-Cherit,
Silvia Méndez-Flores
Issue:
Volume 3, Issue 4, July 2017
Pages:
32-35
Received:
26 February 2017
Accepted:
23 March 2017
Published:
19 October 2017
Abstract: Patients with cat cry or “cri-du-chat” syndrome often present with hallmark signs of the condition. The purpose of this manuscript is to report the findings observed in skin and oral mucosa which produced high morbidity in a 19 year-old female patient with cat cry syndrome, considering the scarce descriptions of the lesions on these anatomical sites. Nutritional, neurological and dermatological manifestations are described; laboratory findings are also included. The impact of clinical findings on inadequate nutritional status of patient is discuss. The approach is emphasized in order to improve the intraoral diagnoses, management and quality of life of this patient.
Abstract: Patients with cat cry or “cri-du-chat” syndrome often present with hallmark signs of the condition. The purpose of this manuscript is to report the findings observed in skin and oral mucosa which produced high morbidity in a 19 year-old female patient with cat cry syndrome, considering the scarce descriptions of the lesions on these anatomical site...
Show More
-
Prevalence of Personality Disorders and Clinical Syndromes Using the Millon Clinical Multiaxial Inventory III (MCMI-III) in an Iranian Clinical Sample
Mahboubeh Dadfar,
David Lester
Issue:
Volume 3, Issue 4, July 2017
Pages:
36-47
Received:
3 September 2016
Accepted:
7 October 2016
Published:
19 October 2017
Abstract: Personality objective inventories are commonly used for diagnosis of personality disorders. Personality assessment is effective in diagnosis, prognosis and treatment of psychiatric outpatients and in patients. Comorbid personality disorders and clinical syndromes may be more worth condition of the patients. The present study aimed to examine the diagnosis of personality disorders and clinical syndromes using the Farsi version of Millon Clinical Multiaxial Inventory III (3rd ed.; MCMI-III) in Iranian psychiatric outpatients. This was a descriptive cross-sectional study. The subjects of the project were 737 psychiatric outpatients. They were referred to the psychiatric and psychological clinics at the School of Behavioral Sciences and Mental Health-Tehran Institute of Psychiatry affiliated to Iran University of Medical Sciences, Tehran, Iran. The subjects were selected using convenience sampling during years of 2010-2015 and evaluated by the MCMI-III computerized Farsi version. Data were analyzed by descriptive methods and t test using SPSS/WIN 16.0 program. Results showed that the most frequent of personality disorders were Depressive (2B), Compulsive (7), and Histrionic (4); with double code types of Depressive- Dependent (2B3); and Histrionic- Depressive (42B) combinations. The most frequent of moderate clinical syndrome were Anxiety (A), and Dysthymia (D) and the severe syndromes was Thought Disorder (SS); with double codes of clinical syndromes of Anxiety- Post-Traumatic Stress Disorder (AR). There were significant differences between women and men patients in mean scores of some MCMI-III scales. Women had higher scores in Validity Scales of Disclosure (X) and Debasement (Z) than men. Depressive, Passive-Aggressive (Negativistic) (8A), Self-Defeating (8B) and Borderline (C) personality disorders were the most common in women than men. By contrast, Compulsive (7) personality disorder was the most common in men compare to women. Anxiety, Somatoform (H), Bipolar: Manic (N), Dysthymia (D), and Post-Traumatic Stress Disorder (R), Thought Disorder (SS), and Major Depression Disorder (CC) were the most common in women than men. The prevalence of diagnosis personality patterns and clinical syndromes in Iranian psychiatric outpatients is high and this should be taken into account in their assessment and treatment planning. Using of available sample and lack of random sample; possibility of comorbidity of other mental disorders with main diagnosis are limitations of the study. Utilization of item response theory (IRT); Structural Clinical Interviews for DSM Axis I and Axis II (SCID-I and SCID-II) along with MCMI-III; and MCMI-IV in an Iranian clinical sample are recommended.
Abstract: Personality objective inventories are commonly used for diagnosis of personality disorders. Personality assessment is effective in diagnosis, prognosis and treatment of psychiatric outpatients and in patients. Comorbid personality disorders and clinical syndromes may be more worth condition of the patients. The present study aimed to examine the di...
Show More
-
Limited Management of Systemic Erythematosus Lupus in Madagascar
Fandresena Arilala Sendrasoa,
Irina Mamisoa Ranaivo,
Naina Harinjara Razanakoto,
Malalaniaina Andrianarison,
Onivola Raharolahy,
Lala Soavina Ramarozatovo,
Fahafahantsoa Rapelanoro Rabenja
Issue:
Volume 3, Issue 4, July 2017
Pages:
48-51
Received:
31 October 2016
Accepted:
27 December 2016
Published:
24 October 2017
Abstract: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that involves multiple organs and has alternating periods of flare-ups and quiescence. SLE requires multiple paraclinical and therapeutic investigations that are not accessible by Malagasy patients. We aim to assess the monthly direct cost in SLE referring to international recommendations. The cost of paraclinical exams and treatment expenses were estimated as a percentage of the MMMS (Malagasy Minimum Monthly Salary). According to international recommendations, the cost of first-line paraclinical exams for SLE diagnosis was 274,2% of the MMMS. The costs of diagnostic tests were 110,9% and 923,4% of the MMMS to research renal and neurological damage, respectively. The monthly cost of pharmacological therapies ranged from 132,2% to 205,9% of the MMMS, depending on the severity of SLE. Clinical examination and affordable paraclinical exams were fundamental in our practice to manage systemic lupus erythematosus lupus. Appropriate recommendations for emergent countries should be come up.
Abstract: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that involves multiple organs and has alternating periods of flare-ups and quiescence. SLE requires multiple paraclinical and therapeutic investigations that are not accessible by Malagasy patients. We aim to assess the monthly direct cost in SLE referring to international recommend...
Show More
