American Journal of Psychiatry and Neuroscience

Volume 4, Issue 2, March 2016

  • Oleic Acid Produces Motor Incoordination and Hypoactivity in Infant Wistar Rats Through GABAA Receptors

    Gabriel Guillén-Ruiz, Blandina Bernal-Morales, Carlos M. Contreras, Jonathan Cueto-Escobedo, Juan Francisco Rodríguez-Landa

    Issue: Volume 4, Issue 2, March 2016
    Pages: 18-25
    Received: 8 March 2016
    Accepted: 18 March 2016
    Published: 31 March 2016
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    Abstract: A mixture of eight fatty acids (linoleic, oleic, palmitic, stearic, myristic, elaidic, lauric, and palmitoleic acids) at similar concentrations that have been identified in human amniotic fluid exerts anxiolytic-like effects similar to diazepam in adult Wistar rats through actions at -aminobutyric acid-A (GABAA) receptors, but unknown is whether a... Show More
  • Evaluation of Nootropic Activity of Persicaria flaccida on Cognitive Performance, Brain Antioxidant Markers and Acetylcholinesterase Activity in Rats: Implication for the Management of Alzheimer’s Disease

    Md. Sahab Uddin, Md. Nasrullah, Md. Sarwar Hossain, Md. Mosiqur Rahman, Md. Shahid Sarwar, Md. Shah Amran, Md. Golam Sadik, Mamunur Rashid, Md. Asaduzzaman

    Issue: Volume 4, Issue 2, March 2016
    Pages: 26-37
    Received: 10 February 2016
    Accepted: 18 April 2016
    Published: 14 May 2016
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    Abstract: Oxidative stress is the leading cause of neurodegenerative diseases, especially Alzheimer´s disease (AD). The plant Persicaria flaccida (PF) is known in Bengali as red Biskatali belongs to family Polygonaceae. Preliminary studies have shown the antioxidant, anti-inflammatory, analgesic, neuroprotective activities of Biskatali. In this consequence, ... Show More