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Assessing of Depression Status and Influencing Factors Were Associated with Hospitalized Patients with 6 Chronic Diseases
Yanfang Deng,
Jinglan Luo,
Ping Li
Issue:
Volume 8, Issue 2, June 2020
Pages:
26-29
Received:
8 April 2020
Accepted:
23 April 2020
Published:
4 June 2020
Abstract: Objective: To assess depression status and influencing factors were associated with hospitalized patients with 6 chronic diseases. Methods: We collect the data from 485 patients, they agree to join our study. They were diagnosed as one of 6 chronic diseases, such as stroke, coronary heart disease, chronic obstructive pulmonary disease, diabetes, malignant tumor and chronic kidney disease. The diagnosis of time is from January 2018 to July 2018. Additionally, we collect the information by questionnaires, the information includes patient basic information, patient business situation and depression status. The questionnaires include Self-made patients general information questionnaire and patient health questionnaire (PHQ-9) which is base on the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV). Result: Base on results of demographic data analysis, 205 out of 485 patients with chronic diseases had depressive symptoms. The incidence of depressive symptoms was 42.3%, that include 101 cases (49.3%) of mild depression, 62 cases (30.2%) of moderate depression and 42 (20.5%) cases of major depression. In research of depressive symptoms in patients with chronic diseases, those data show statistical significance in demographic analysis as independent variables, such as education level, average monthly medical expenses, duration of illness, number of hospitalizations and self-care ability. Conclusion: On the hand, the course of the disease is positively correlated with the incidence of depressive symptoms, the longer the course the higher the incidence of depression, consistent with similar studies. On another hand, the worse the self-care ability, the higher the incidence of depression, consistent with the results of similar studies.
Abstract: Objective: To assess depression status and influencing factors were associated with hospitalized patients with 6 chronic diseases. Methods: We collect the data from 485 patients, they agree to join our study. They were diagnosed as one of 6 chronic diseases, such as stroke, coronary heart disease, chronic obstructive pulmonary disease, diabetes, ma...
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Evaluating the Effect of Repetitive Transcranial Magnetic Stimulation (rTMS) and Humanistic Care Treatment on Cognitive Impairment Patients
Yingxue Zhong,
Danfeng Jiang,
Guoqiang Zheng
Issue:
Volume 8, Issue 2, June 2020
Pages:
30-32
Received:
29 April 2020
Accepted:
18 May 2020
Published:
4 June 2020
Abstract: Objective: To evaluate the effect of repetitive transcranial magnetic stimulation (rTMS) and Humanistic care treatment on Cognitive impairment patients. Methods: We invested 60 patients to join our study who were diagnosed as cerebrovascular disease or alzheimer disease, the diseases are cognitive impairment. Their diagnose time is from January 2019 to December 2019. We randomly assign the participants to two groups, that include control group (n=30) and intervention group (n=30). In control group, participants receive conventional responsibility mode of nursing. Intervention group participants receive humanistic care model in treatment process. Result: In Unplanned extubation rate of rTMS, the control group has more case of Unplanned extubation, it also has higher Unplanned extubation rate than that of intervention group [3 (10.0%) vs 7 (23.3%)]. In incidence of agitation, it shows the cases of intervention group are less than that of control group, and it is statistical significance (8 vs 13, p=0.014). In accurate response research, the intervention group has better performance in accurate response test, its accurate response rate is 86.7% and the case of accurate response is 26, that is better than that of control group in our research result. Conclusion: The effect of repetitive transcranial magnetic stimulation (rTMS) and Humanistic care treatment is good for improve treatment outcome of cognitive impairment.
Abstract: Objective: To evaluate the effect of repetitive transcranial magnetic stimulation (rTMS) and Humanistic care treatment on Cognitive impairment patients. Methods: We invested 60 patients to join our study who were diagnosed as cerebrovascular disease or alzheimer disease, the diseases are cognitive impairment. Their diagnose time is from January 201...
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Neurochemical Theory of Epilepsy Pathogenesis in It's Neurological and Mental Manifestations
Alexander Kharibegashvili
Issue:
Volume 8, Issue 2, June 2020
Pages:
33-39
Received:
23 April 2020
Accepted:
12 June 2020
Published:
4 July 2020
Abstract: In the article, in light of the hypothesis about the pathogenesis of epilepsy the author considers certain clinical manifestations of epilepsy, touches upon the neurochemistry of behavior, as well as neurotransmitter hypothesis of schizophrenia. According to the hypothesis, in epileptic patients, epileptogenic substances are permanently accumulating in the brain, which in the course of epileptic activity in the brain undergo metabolic changes requiring their removal from the organism. When the concentration of epileptogenic substances in the brain reaches a threshold value, they cause a seizure, and in lower concentrations, they cause epileptic activity typical for the interictal period. In the context of this hypothesis, there are discussed the clinical signs of epilepsy such as forced normalization, reinforcement epilepsy activity during the sleep deprivation and one of the paradoxical effect of antiepileptic drugs such as phenomen when antiepileptic drugs prescribed cause an improvement of the electroencephalographic image but the clinical deterioration and increasing frequency of seizures, and the change of antiepileptic drugs give us the opposite results: improvement of the clinical picture and the deterioration of the electroencephalographic image. According to the supplemented hypothesis, epileptogenic substances, except that, during epileptic activity in the brain undergo metabolic transformations necessary for their removal from the body; there are also alternative transformation neurochemical pathways necessary for their further removal (elimination) from the organism. The hypothesis discusses the modern principles of epilepsy treatment. It was proposed to call the phenomenon “clinical-electroencephalographic dissociation” when the anti-epileptic drugs are associated with the improved electroencephalographic pattern, but with the deterioration of the clinic and frequent seizures, and the drug change leads to the opposite—the improvement of the clinical picture and the EEG deterioration. Forced normalization is considered as one of the manifestations of epilepsy aggravation and “clinical-electroencephalographic dissociation”. When reviewing biological antagonism of schizophrenia and epilepsy the author suggests a hypothesis that if an area of the brain producing epileptogenic substances and an area of the brain producing endogenic psychogenic substances causing psychopathology coexist simultaneously, then, in the event of a generalized convulsive seizure involving the brain in full, epileptogenic as well as psychogenic substances are released. At the same time epilepsy is demonstrated, while schizophrenia is not. The same could be the mechanism of therapeutic activity (effect) of electroconvulsive therapy.
Abstract: In the article, in light of the hypothesis about the pathogenesis of epilepsy the author considers certain clinical manifestations of epilepsy, touches upon the neurochemistry of behavior, as well as neurotransmitter hypothesis of schizophrenia. According to the hypothesis, in epileptic patients, epileptogenic substances are permanently accumulatin...
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