Archive:: Chemical and Biomolecular Engineering:: Science Publishing Group

Volume 4, Issue 2, June 2019

Isolation and Characterization Photo Degradation Impurities of Drug Product Olopatadine Hydrochloride by Spectral Techniques

Shivaji Jadhav, Amit Gosar, Amit Jadkar, Rajesh Ankam, Chandrakant Dhatrak

Issue: Volume 4, Issue 2, June 2019

Pages: 31-36

Received: 8 April 2019

Accepted: 28 May 2019

Published: 17 June 2019

DOI: 10.11648/j.cbe.20190402.11

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Abstract: Unknown impurities were detected during Photo degradation of Olopatadine Hydrochloride ophthalmic solution 0.5% (w/v) when analyzed using the High performance liquid chromatographic technique with Photo Diode Array Detection. For further investigation was carried out by isolating these impurities from impurity rich sample of Olopatadine Hydrochlori... Show More

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The Method of Obtaining Interfacial Catalysis Azerbaijan State University of Oil and Industry

Mikayilova Mehriban Rahil, Mustafayeva Rena Eldar

Issue: Volume 4, Issue 2, June 2019

Pages: 37-39

Received: 3 April 2019

Accepted: 13 June 2019

Published: 26 June 2019

DOI: 10.11648/j.cbe.20190402.12

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Abstract: Since the reaction proceeds very smoothly under these conditions, the main products are obtained in high yields, including with a high degree of frequency. Increasing the amount of DB18K6 from 0.001 to 0.004 moll and carrying out the reaction at a temperature of 1000°C for 70 minutes in the system: 1, 2 dimethyl cyclohexane, KOH (0.4 moll), dioxin ... Show More

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