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Development Trend and Application of Star Soil Sampler Impact Mechanism Technology
Lu Mingyu,
Zhang Ming,
Liu Shuo,
Zhang Xingwang
Issue:
Volume 7, Issue 1, February 2019
Pages:
1-8
Received:
6 December 2018
Published:
1 February 2019
Abstract: With the development of global space technology, technologies of planet soil detection, sampler and return will become more and more important in the field of deep space exploration in the future. The space environment detection and sampling tasks in deep space exploration have the characteristics of high vacuum, low gravity, intense temperature change, complex composition of target materials, and limited energy and power consumption of the sampler. Therefore, in the extremely harsh space environment, the ability of the sampler to break the surface material of the celestial body directly determines the completion of the sampling task. In view of the above situation, the introduction of impact excitation in the extraterrestrial celestial sampling returning device can improve the intrusion ability of the sampling device to hard materials, and can effectively reduce the static pressure and total energy required during the drilling process, and the vibration brought by the drilling device is also It is beneficial to chip removal and troubleshooting such as card drilling, which can effectively improve the drilling and crushing efficiency of drilling and mining equipment. Therefore, impact sampling is an ideal sampling method for deep space detection.The characteristic and rock breaking mechanism of impact load are analyzed by this paper, the application status and development trend of impact drilling space sampler were investigated, the research direction and suggestion of the impact mechanism of planet soil sampler are put forward.
Abstract: With the development of global space technology, technologies of planet soil detection, sampler and return will become more and more important in the field of deep space exploration in the future. The space environment detection and sampling tasks in deep space exploration have the characteristics of high vacuum, low gravity, intense temperature ch...
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Application of Intermediate Length Catheter in Palliative Treatment of Tumor
Hengyu Cai,
Qi Jiang,
Qun Lou,
Yixuan Wang,
Hongyan Guo
Issue:
Volume 7, Issue 1, February 2019
Pages:
9-12
Received:
17 January 2019
Published:
8 March 2019
Abstract: Today’s society,tumors have become the number one killer treateningt the well-being of human beings.At present,China swollen and persistent disease rises every year.Bring a heavy burden on family and society.Although the treatment is becoming more and more popular,it is still the main cause of death and chronic colouring disease.In particular,it is becoming more and more important for the clinicians to pay attention to the fact that it is impossible to cure the disease,so the palliative treatment can lead to a high quality of life in the final stage of their life.In Auntie, pulse-sparing infusion is still the main mode of administrain.In the course of platinum solution treatment,repaeted puncture not only increased the patient’s pain, but also occurred with plstinum fluid. The medium length of the guide was chosen, Procedures for operation, not only less puncture and blowing number, through the patient pain, complications also rare.The goal of Treatment of Patients with Swelling and Peeding Benefits obtained sood results.
Abstract: Today’s society,tumors have become the number one killer treateningt the well-being of human beings.At present,China swollen and persistent disease rises every year.Bring a heavy burden on family and society.Although the treatment is becoming more and more popular,it is still the main cause of death and chronic colouring disease.In particular,it is...
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Research Progress of Exosome Non-coding RNA in Cancer
Jiajia Jin,
Shengrong Wu,
Xiaoyan Lu,
Zixiao Huang,
Mei’e Jia,
Xiangyi He
Issue:
Volume 7, Issue 1, February 2019
Pages:
13-17
Received:
26 January 2019
Published:
8 March 2019
Abstract: Exosomes, secreted by both normal cells and tumor cells, are small membrane vesicle bodies that presented in saliva, blood, urine and other body fluids. The proteins, lipids, non-coding RNA and other components in exosomes functioned profoundly in cell communication and signal transduction, and tumor-derived exosomes can activate various signaling pathways and influence tumor microenvironment to participate in the tumor proliferation and migration. Non-coding RNAs play a crucial role in regulating gene expression, such as cell physiology, tumor development and tumor immunity. At present, researchs focused on exosome non-coding RNA, especially miRNA and lnRNA. In this review, we will review the tumor-derived exosome miRNA and lnRNA in tumorigenesis and development.
Abstract: Exosomes, secreted by both normal cells and tumor cells, are small membrane vesicle bodies that presented in saliva, blood, urine and other body fluids. The proteins, lipids, non-coding RNA and other components in exosomes functioned profoundly in cell communication and signal transduction, and tumor-derived exosomes can activate various signaling ...
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Reliability Analysis of Safety Critical Computer System Considering Common Cause Failure
Issue:
Volume 7, Issue 1, February 2019
Pages:
18-23
Received:
7 March 2019
Published:
8 March 2019
Abstract: The rail transit operation control system and nuclear reactor control system are extremely high for safety and reliability, especially the high speed maglev of more than 600 kilometers per hour. Therefore, the effect of common cause failure on the reliability of safety critical computer must be considered.The safety critical system is the key of the above-mentioned safety demanding system. In this paper, the structure and working principle of a safety critical computer with two-out-of-three and double two-out-of-two are analyzed.Considering the common cause failure and maintenance rate, by using Markov model, the reliability models of safety critical computer system with with two-out-of-three and double two-out-of-two are established. The simulation results show that the existence of common cause failure greatly reduces the reliability of the system. The maintenance rate can improve the reliability of the system. At the same time, considering the common cause failure and the maintenance rate, it is proved that the reliability of the two-out-of-three safety critical computer system is higher than double two-out-of-two safety critical computer system. Therefore, it provides theoretical support for the design of the subsequent differentiated security computer platform.
Abstract: The rail transit operation control system and nuclear reactor control system are extremely high for safety and reliability, especially the high speed maglev of more than 600 kilometers per hour. Therefore, the effect of common cause failure on the reliability of safety critical computer must be considered.The safety critical system is the key of th...
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The Teaching Reform of Plastic Molding Process and Mold Design
Ren Yanxia,
Jin Fengfeng,
Cui Pei,
Qin Guofang,
Sun Haiyan Haiyan
Issue:
Volume 7, Issue 1, February 2019
Pages:
18-21
Received:
19 January 2019
Published:
8 March 2019
Abstract: This paper introduces the reform of the course "plastic Molding Technology and Mould Design" in the aspects of class form, course content, teaching mode, teaching means, examination method and so on. Through the reform of the above aspects, the theoretical study can be closely combined with the practical contents such as UG mold design, mold disassembly and assembly, etc. students no longer feel boring and difficult to understand in their study, and their enthusiasm and initiative in learning have been obviously improved. In addition, this paper also introduces the overall design of the course, its content carrier comes from life products or related competition models, reflecting the practicability of the course. This reform is not only suitable for the groups with poor foundation in higher vocational colleges, but also suitable for the students with good foundation.
Abstract: This paper introduces the reform of the course "plastic Molding Technology and Mould Design" in the aspects of class form, course content, teaching mode, teaching means, examination method and so on. Through the reform of the above aspects, the theoretical study can be closely combined with the practical contents such as UG mold design, mold disass...
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Rational Critique of the Genome Editing Infants Event
Zhai Jiancai,
Mei Lin,
Song Tonglin,
Zhang Xiaolin,
Huang Jun
Issue:
Volume 7, Issue 1, February 2019
Pages:
22-25
Received:
17 January 2019
Published:
28 April 2019
Abstract: Genome editing is a new technology in BME and will be widely used in medicine. The birth of genome-edited babies has resulted in serious adverse consequences, for disobeying the international consensus that gene-editing embryos should not be used for pregnancy purposes, disregarding the existing laws and ethical norms of our country, ignoring the scientific warning of dangers of the immature medical practice and betraying the medical spirit and professional integrity. The rational criticism of this incident makes all scientific and medical communities soberly realize that medicine is a weapon created by human civilization for the benefit, which has both material function and spiritual value. Any medical activity could not betray its spiritual value, that is, medical humanistic value. Medical laws and ethics can support and regulate medical activities, guiding to selectively perform the role of science and technology in medical practice, and enable medicine to completely serve the human rights and health protection, rather than to guide gaining benefits for small interest groups. The rational criticism of events must have critical rationality, especially the proper grasp and implementation of the moral norms towards the people concerned with events.
Abstract: Genome editing is a new technology in BME and will be widely used in medicine. The birth of genome-edited babies has resulted in serious adverse consequences, for disobeying the international consensus that gene-editing embryos should not be used for pregnancy purposes, disregarding the existing laws and ethical norms of our country, ignoring the s...
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The Functional Dysconnectivity Within the Emotion Regulation System Is Associated with Anhedonia in Major Depressive Disorder
Zongling He,
Fengmei Lu,
Huafu Chen
Issue:
Volume 7, Issue 1, February 2019
Pages:
26-31
Received:
22 February 2019
Published:
28 April 2019
Abstract: Objective: The neuro-pathphysiological abnormalities of Major Depressive Disorder (MDD) have been reported to be distributed in emotion regulation system, involving the prefrontal cortex, limbic and subcortical nuclei[8]. Anhedonia is recognized as a hallmark of MDD. Characterizing the aberrant functional connectivity (FC) within this system and exploring the relationships between these dysconnectivity and anhedonia will help us better look into the neuro-pathophysiological mechanisms underlying MDD. Methods: Sixty-three MDD and 63 healthy controls (HCs) underwent resting-state functional magnetic resonance imaging (rsfMRI). The spatial pairwise clustering (SPC) analysis and network-based statistic (NBS) were used to explore the alterations in the emotion regulation system of MDD from voxel level to network level. The alterations in FC and their relationships with anhedonia symptom were explored. Result: This study suggested that the aberrant FC subnetworks within the emotion regulation system mainly involved in prefrontal-limbic system, prefrontal-striatum system and within the limbic system. In addition, the aberrant subnetworks of prefrontal cortex/anterior cingulate cortex and amygdala/hippocampus could predict the anhedonia symptom in MDD. Conclusion: These findings demonstrated that MDD showed characteristic pathological alterations of the emotion regulation system. Moreover, the abnormal FC between the prefrontal cortex/anterior cingulate cortex and the amygdala/hippocampus might be the potential neural markers of depression-related anhedonia.
Abstract: Objective: The neuro-pathphysiological abnormalities of Major Depressive Disorder (MDD) have been reported to be distributed in emotion regulation system, involving the prefrontal cortex, limbic and subcortical nuclei[8]. Anhedonia is recognized as a hallmark of MDD. Characterizing the aberrant functional connectivity (FC) within this system and ex...
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Study on the Dynamic Prediction Method of ECD in Horizontal Well Drilling
Ma Xianming,
Guan Zhichuan,
Luo Ming,
Li Wentuo,
Pan Rui
Issue:
Volume 7, Issue 1, February 2019
Pages:
32-38
Received:
11 January 2019
Published:
28 April 2019
Abstract: Well pressure and ECD control is one of the most important things in horizontal well drilling. This paper establish horizontal borehole pressure and ECD management considered seaside, temperature, drill pipe eccentric, drill pipe rotation and cutting bed though research horizontal well drilling. Sensitive factors like drill fluid density, drill fluid viscosity and so on has been found though analyzed the sensitive of ECD to drilling parameter. ECD real-time correction with different condition has been proposed though dimensionless comparison of factors. The first correction based on measured export parameters on the ground and use pump pressure to verify the correction. The second correction use trial method after compared pressure curve measured in down hole with model curve, verify the correction by pattern contrast. Precise ECD data can obtained use real-time correction mentioned to correct ECD management, ensure drilling safety in narrow density window.
Abstract: Well pressure and ECD control is one of the most important things in horizontal well drilling. This paper establish horizontal borehole pressure and ECD management considered seaside, temperature, drill pipe eccentric, drill pipe rotation and cutting bed though research horizontal well drilling. Sensitive factors like drill fluid density, drill flu...
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Establishment of Wellbore Temperature Field During High Temperature and High Pressure Well Cementing in Western South China Sea
Pan Rui,
Guan Zhichuan,
Luo Ming,
Ma Xianming,
Wang Kai,
Wang Bin
Issue:
Volume 7, Issue 1, February 2019
Pages:
39-44
Received:
18 January 2019
Published:
28 April 2019
Abstract: The western part of south China sea is characterized by high geothermal gradient, abnormal overpressure development and narrow formation pressure window in the deep part of the basin. In the process of cementing, the annulus has high pressure consumption, high risk of leakage, and significant influence of temperature on the rheology and hydration of cement slurry. In order to accurately determine the rheological and rheological parameters of cement slurry and prevent possible well leakage, overflow and even blowout accidents in the process of cementing, it is necessary to establish a wellbore temperature field model in the process of cementing. Based on the data of the actual drilling well, the variation of wellbore temperature under different pump displacement and circulation time is analyzed. The results show that the annular temperature is larger than the annular temperature at the beginning, and the annular temperature is larger than the annular temperature with the increase of depth. With the increase of displacement, the bottom hole temperature decreases and the outlet temperature increases. With the extension of the cycle time, the bottom hole temperature decreases and the outlet temperature increases. When the cycle time reaches a certain value, the bottom hole and outlet temperature remain basically unchanged.
Abstract: The western part of south China sea is characterized by high geothermal gradient, abnormal overpressure development and narrow formation pressure window in the deep part of the basin. In the process of cementing, the annulus has high pressure consumption, high risk of leakage, and significant influence of temperature on the rheology and hydration o...
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Lowpass Filter with Wide Stopband Based on T-Shaped Resonator Loaded Step-Impedance Hairpin Resonator
Zhong Lunjie,
Zuo Qiliang,
Xu Jinping
Issue:
Volume 7, Issue 1, February 2019
Pages:
45-49
Received:
19 April 2019
Published:
23 May 2019
Abstract: A lowpass filter with wide stopband based on stepped impedance hairpin resonator is proposed. Multiple transmission zeros are created in the stopband region by different size T-shaped resonator to achieve wide stopband. A lowpass filter with 3dB cutoff frequency (fc) at 3.2GHz is designed, simulated and fabricated. Experimental results indicate that stopband can be extended to more than 7fc with a rejection level of 20dB after loading T-shaped resonator. The insertion loss is lower than 0.4dB and return loss is better than 16dB in the passband. Excluding the feed lines, the size of the filter is less than 0.26λg X 0.06λg. The modified filter is of good value in engineering application for its small size, sharp cutoff frequency response and wide stopband.
Abstract: A lowpass filter with wide stopband based on stepped impedance hairpin resonator is proposed. Multiple transmission zeros are created in the stopband region by different size T-shaped resonator to achieve wide stopband. A lowpass filter with 3dB cutoff frequency (fc) at 3.2GHz is designed, simulated and fabricated. Experimental results indicate tha...
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Design of an E-band Power Dividing/Combining Network Based on H-Plane 3dB Directional Couplers
Chen Peng,
Wan Peng,
Xu Jinping
Issue:
Volume 7, Issue 1, February 2019
Pages:
50-55
Received:
19 April 2019
Published:
23 May 2019
Abstract: In this paper, an E-band four-channel power dividing/combining network is designed based on H-plane 3dB waveguide directional couplers. Firstly, the waveguide H-plane 3dB directional coupler with working frequency of 71~78GHz is designed by HFSS to achieve low loss and high isolation. According to the phase relationship of each port of the coupler, the topology of the power dividing/combining network is worked out, and then the HFSS simulation analysis model for the whole network is established. On the basis of simulation analysis and optimization, a prototype of the four-channel power dividing/combining network of the E-band were manufactured. A back-to-back testing scheme, where a one-fourth dividing network and a four-in-one combining network is jointed together, is adopted to facilitate the testing work. The measured results show that the overall insertion loss of the power dividing/combining network is less than 2.2dB, with a typical value of 1.7dB, in the frequency range of 72~77GHz.
Abstract: In this paper, an E-band four-channel power dividing/combining network is designed based on H-plane 3dB waveguide directional couplers. Firstly, the waveguide H-plane 3dB directional coupler with working frequency of 71~78GHz is designed by HFSS to achieve low loss and high isolation. According to the phase relationship of each port of the coupler,...
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Application of Full Digital Simulation Test Environment in Aerospace Software Testing
Xue Shuai,
Zhao Long,
Hu Xiaoxi
Issue:
Volume 7, Issue 1, February 2019
Pages:
56-60
Received:
22 April 2019
Published:
23 May 2019
Abstract: With the significant increase in the degree of informationization of spacecraft, higher requirements are placed on the reliability of aerospace software. Therefore, the position of software testing in the software development cycle is particularly important. The current software testing environment has significant limitations for achieving high reliability and high quality requirements for aerospace software. In order to solve this problem and further improve the quality of software testing, this paper uses the full digital simulation test environment to test the aerospace software. This paper first analyzes the current test conditions and shortcomings of the aerospace software, then introduces the basic concept of the full digital simulation test environment, and finally applies the full digital simulation test environment to the aerospace model software test, improving the quality and efficiency of software testing. The application results show that the full digital simulation test environment has stronger versatility and flexibility than other software test environments, and is more suitable for current aerospace software testing.
Abstract: With the significant increase in the degree of informationization of spacecraft, higher requirements are placed on the reliability of aerospace software. Therefore, the position of software testing in the software development cycle is particularly important. The current software testing environment has significant limitations for achieving high rel...
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