Comparison of Fitness Parameters in Different Species of Drosophila
Suhasini L. Kudupali,
Shivanna N.
Issue:
Volume 1, Issue 1, February 2013
Pages:
1-6
Published:
20 February 2013
Abstract: The fitness parameter has been studied in Drosophila melanogaster, D. bipectinata，D. malerkotliana and D. ananassae. 7 day aged virgin flies were used for mating experiment, it revealed that, mating latency is more in D. malerkotliana and less in D. melanogaster. Mating time of D. melanogaster is more and it is less in D. ananassae D. bipectinata takes more time to remate and D. melanogaster takes less time to remate. Mating time, fecundity, productivity and viability of virgin is more than mated male in all the species except, D. melanogaster. Even though D. melanogaster has more percentage of viability it takes more time in mating. The mating time is less in D. ananassae whereas, fecundity, productivity and percentage of viability is more than other species.
Abstract: The fitness parameter has been studied in Drosophila melanogaster, D. bipectinata，D. malerkotliana and D. ananassae. 7 day aged virgin flies were used for mating experiment, it revealed that, mating latency is more in D. malerkotliana and less in D. melanogaster. Mating time of D. melanogaster is more and it is less in D. ananassae D. bipectinata ...
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Molecular Dynamics Study of the Effect of Induced Mutations on the Protein Structures Associated with Diseases of A Radiobiological Nature
Issue:
Volume 1, Issue 1, February 2013
Pages:
7-16
Published:
20 February 2013
Abstract: The induced mutations in biological molecules, such as DNA and proteins, have quite a different nature (envi-ronmental factors, viruses, ionizing radiation, mutagenic chemicals, inherited genetic alterations, etc.). Induced mutations can destroy the existing chemical (hydrogen) bonds in the native molecular structures or, on the contrary, create new chem-ical (hydrogen) bonds that do not normally exist there. In protein structures, the cause of such changes might be the substi-tution of one or several specific amino acid residues (point mutations). At the atomic level, the replacement of one amino acid residue by another causes essential modifications of the molecular force fields of the environment, which can break important hydrogen bonds underlying the structural stability of biological molecules. In this work, based on molecular dy-namics (MD) method, we demonstrate the effect of mutational structure changes on several biological protein models (the p53 oncoprotein, visual pigment rhodopsin, cyclin-dependent kinase, and recA protein). Molecular dynamics simulation is a powerful tool in investigating the structure properties of biological molecules on the atomic and molecular levels, and it has been widely used to study the structural conformational behavior of proteins. We also discuss the scenario of the mutation effects associated with different kinds of diseases that could develop and take place in physiological conditions.
Abstract: The induced mutations in biological molecules, such as DNA and proteins, have quite a different nature (envi-ronmental factors, viruses, ionizing radiation, mutagenic chemicals, inherited genetic alterations, etc.). Induced mutations can destroy the existing chemical (hydrogen) bonds in the native molecular structures or, on the contrary, create ne...
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Hemodynamic Changes Caused by Exposure of Animals with Acute Immobilization Stress to Continuous Terahertz Radiation
V. F. Kirichuk,
V. V. Velikanov,
T. S. Velikanova,
O. N. Antipova,
E. V. Andronov,
A. N. Ivanov,
S. S. Parshina,
N. E. Babichenko,
T. S. Kiriyazi,
E. V. Ponukalina,
I. V. Smyshlyaeva,
L. K. Tokaeva,
A. A. Tsymbal
Issue:
Volume 1, Issue 1, February 2013
Pages:
17-23
Published:
20 February 2013
Abstract: Experimental simulation of hemodynamic disorders during acute immobilization stress has shown that expo-sure to continuous terahertz radiation with frequencies equal to absorption and emission frequencies of nitrogen oxide (150.176-150.664 GHz) and atmospheric oxygen (129.0 ± 0.75 GHz) for 5, 15 and 30 minutes allows to revert post-stress hemodynamic changes in great vessels. This allows using terahertz electromagnetic radiation with frequencies equal to absorption and emission frequencies of nitrogen oxide (150.176-150.664 GHz) and atmospheric oxygen (129.0 ± 0.75 GHz) to treat hemodynamic disorders accompanying some of pathologic diseases.
Abstract: Experimental simulation of hemodynamic disorders during acute immobilization stress has shown that expo-sure to continuous terahertz radiation with frequencies equal to absorption and emission frequencies of nitrogen oxide (150.176-150.664 GHz) and atmospheric oxygen (129.0 ± 0.75 GHz) for 5, 15 and 30 minutes allows to revert post-stress hemodynam...
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