Assessment of Serum Zinc and Copper Levels, and Cu / Zn Ratio Among Patients of Côte D’Ivoire with Type 2 Diabetes
N’Guessan Assieoussou Jean-Luc,
Boyvin Lydie,
Bahi Gnogbo Alexis,
Moke-Bedji Louise Odile,
Yaye Yapi Guillaume,
Ankotche Amos,
Djaman Allico Joseph
Issue:
Volume 8, Issue 4, December 2020
Pages:
57-61
Received:
5 November 2020
Accepted:
20 November 2020
Published:
27 November 2020
Abstract: Type 2 diabetes or diabetes mellitus is a metabolic disorder characterized by an increase in blood sugar level. It is caused by a lack of insulin secretion, insulin action, or both. There are approximately 501,530 people living with diabetes in Côte d’Ivoire with an estimated prevalence of 5.19% in 2013. Unfortunately impairment of zinc and copper leads to increased oxidative stress, insulin resistance and diabetic complications. The study aimed to assess the zinc and copper status in patients with type 2 diabetes. This study involved 80 type 2 diabetics and 80 non-diabetic as controls. Glycated hemoglobin (HbA1c) was analyzed in whole blood using the Hitachi Roche Cobas C311. The serum assays of zinc and copper then of glycemia were carried out using a flame-air / acetylene atomic absorption spectrophotometer (AAS) of the brand Varian Spectr AA-20 Victoria, Australia and on the Cobas C311 respectively. A significant decrease in zinc content (P ˂ 0.0001) and a significant increase in copper content as well as the Cu / Zn ratio (P ˂ 0.0001) were observed in type 2 diabetic patients compared to non-diabetic control. The lower serum zinc values and the high Cu / Zn ratio could justify the high level of oxidative stress in patients with type 2 diabetes. Assessment of zinc and copper is essential in the monitoring of complications due to type 2 diabetes.
Abstract: Type 2 diabetes or diabetes mellitus is a metabolic disorder characterized by an increase in blood sugar level. It is caused by a lack of insulin secretion, insulin action, or both. There are approximately 501,530 people living with diabetes in Côte d’Ivoire with an estimated prevalence of 5.19% in 2013. Unfortunately impairment of zinc and copper ...
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GGE Biplot Stability Analysis of Seed Yield in Teff (Eragrostis tef (zucc.) Varieties in South West Ethiopia
Afework Legesse,
Tegegn Belete
Issue:
Volume 8, Issue 4, December 2020
Pages:
62-67
Received:
12 November 2020
Accepted:
30 November 2020
Published:
28 December 2020
Abstract: Tef (Eragrostis tef (zucc.) is one of the major cereal crop grown in Ethiopia where it is staple food for about 50 million people. Among many factors contributed to low production and productivity of tef lack of widely adopted improved tef variety is one of the factors. The experiment was conducted in south western Ethiopia across six test locations during the 2019 cropping seasons to study the nature of GEI on grain yield of tef and to classify environments based on the performance of genotypes. A total of seven tef varieties were laid out randomized complete block design with three replicates at each site. The Analysis of variance revealed highly significant difference for environment, genotype and genotype by environment interaction (p<0.001). Large proportion of the variation was explained by the environmental effect (69.22%) followed by the GEI effect (20.19%) and genotypes (7.5%) of the overall variation. GGE biplot analysis showed that PC1 and PC2 accounted for 42.37% and 30.42% of GGE sum of squares, respectively, explained 72.79% of the total variance. The six locations were divided in to three mega environments G28, G22 and G25 being the best varieties in each of the mega environments. However, G28 had the highest stability out of these three varieties. E6, E5 and E3 were ideal environments or the most suitable taste location for Teff breeding in the region, while E4 followed by E1 and E2 is a less desirable as testing environment.
Abstract: Tef (Eragrostis tef (zucc.) is one of the major cereal crop grown in Ethiopia where it is staple food for about 50 million people. Among many factors contributed to low production and productivity of tef lack of widely adopted improved tef variety is one of the factors. The experiment was conducted in south western Ethiopia across six test location...
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