Biochemical Study of the Effects of Insulin Resistance on Sex Hormones in Men and Women Type-2 Diabetic Patients / Meisan-Iraq
Adnan Jassim Mohammed Al-Fartosy,
Ibrahim Majar Mohammed
Issue:
Volume 5, Issue 5, October 2017
Pages:
79-88
Received:
12 August 2017
Accepted:
28 August 2017
Published:
12 September 2017
Abstract: Obesity, a case accompanied by increased insulin resistance, is associated with low follicle stimulating hormone, luteinizing hormone, total testosterone and progesterone and estradiol levels. As there is no scientific report on diabetes complications and its effects on type 2 diabetic patients in the province of Meisan (southern of Iraq), the present investigation was done to evaluate the levels of body mass index, insulin resistance and the levels of sex hormones in serum of both men and women type 2 diabetic patients. Data obtained in the present study, show a significant increase in insulin resistance level (4.24 ± 0.57 Vs. 1.36±0.23 and 4.31 ± 0.59 Vs. 1.18 ±0.13, P < 0.05) respectively, in men and women type 2 diabetic patients compared to control. Also, the present study show a significant decrease in follicle stimulating hormone level (7.24±1.14 Vs. 12.79 ±0.87 and 38.14 ± 4.44 Vs. 54.16 ± 3.64, P < 0.05), a significant decrease in luteinizing hormone level (5.32 ± 0.74 Vs. 7.54± 1.27 and 30.12 ± 4.20 Vs. 43.33±2.07, P < 0.05), a significant decrease in testosterone level (4.69 ± 0.92 Vs. 8.20 ± 2.2 and 0.57 ± 0.11 Vs. 0.69± 0.21, P < 0.01), a significant decrease in progesterone level (0.25 ±0.03 Vs. 0.42 ± 0.10 and 0.30 ± 0.04 Vs. 0.46± 0.12, P < 0.05) and a significant decrease in estradiol level (25.04 ± 3.35 Vs. 33.80±8.4 and 34.33 ± 4.21 Vs. 41.42±5.64, P < 0.05) respectively, in men and women type 2 diabetic patients compared to control. In conclusion, the findings further demonstrated that insulin resistance plays an important role in the pathogenesis of many human diseases, such as diabetes, obesity, and reduction of fertility. Therefore, the associated of obesity and increased insulin resistance is accompanied by low levels of follicle stimulating hormone, luteinizing hormone, testosterone, progesterone and estradiol in both men and women.
Abstract: Obesity, a case accompanied by increased insulin resistance, is associated with low follicle stimulating hormone, luteinizing hormone, total testosterone and progesterone and estradiol levels. As there is no scientific report on diabetes complications and its effects on type 2 diabetic patients in the province of Meisan (southern of Iraq), the pres...
Show More
Removal of Ciprofloxacin Hydrochloride from Aqueous Solution by Pomegranate Peel Grown in Alziedab Agricultural Scheme - River Nile State, Sudan
Mutasim Elhag Elhussien,
Maathir Ahmed Abde lraheem,
Rashida Mohammed Hussein,
Mawia Hassan Elsaim
Issue:
Volume 5, Issue 5, October 2017
Pages:
89-96
Received:
29 July 2017
Accepted:
24 August 2017
Published:
13 September 2017
Abstract: Removal of Ciprofloxacin (CIP) antibiotic from aqueous solution onto Activated carbon derived from pomegranate peel wastes collected from Alziedab Agricultural Scheme at River Nile state, Sudan as a novel precursorby chemical activation with Potassium Hydroxide (KOH), at specific condition of carbonization temperature at 500°C and 1 hour as a holding time and detonated as (AC(PPZS)KOH. The obtained material was submitted to measurements of active surface area, Fourier Transform Infrared Spectroscopy (FTIR) analysis and scanning electron microscope (SEM). Batch-adsorption studied had been carried out to examine the adsorption capacity of the AC(PPZS)KOH for the removal of Ciprofloxacin from aqueous solution. The effect of various process parameters like pH, initial antibiotic concentration, adsorbent dose, and contact time, on the efficiency of Ciprofloxacin removal was investigated. Maximum adsorption of Ciprofloxacin on AC(PPZS)KOH, (86.4 ± 5.7%) was observed at pH 8. The optimum adsorbent dose was determined as 0.05 g at 25°C. Initial Ciprofloxacin concentrations has important effect on AC(PPZS)KOH in the studied range (50–300 mg/L) where the removal percentage increases as the antibiotic concentration decrease. The adsorption equilibrium data was well explained by Freundlich isotherm. The results reveal the Langmuir model is not able to describe the experimental data properly, poor less of fitting on AC(PPZS)KOH. The Freundlich isotherm experimental data obtained showed (Correlation Coefficient, R2 = 0.991) higher than Langmuir isotherm, R2 = 0.919). The porous characteristics and adsorption efficiencies of prepared AC(PPZS)KOH were also investigated.
Abstract: Removal of Ciprofloxacin (CIP) antibiotic from aqueous solution onto Activated carbon derived from pomegranate peel wastes collected from Alziedab Agricultural Scheme at River Nile state, Sudan as a novel precursorby chemical activation with Potassium Hydroxide (KOH), at specific condition of carbonization temperature at 500°C and 1 hour as a holdi...
Show More
Antioxidant and Antimicrobial Activities of Exopolysaccharides from Yoghurt Starter
Issue:
Volume 5, Issue 5, October 2017
Pages:
97-101
Received:
30 May 2017
Accepted:
27 June 2017
Published:
18 October 2017
Abstract: The in vitro antimicrobial and antioxidant activities of the exopolysaccharide (EPS) extracted from yoghurt starter were investigated. Antimicrobial activity tests were carried out using disc diffusion methods with Escherichia coli, Staphylococcus aureus and Streptococcus D, Proteus spp and the yeast of Candida albicans. The antioxidant properties were evaluated using the test of DPPH free radical trapping. The results show that the EPS has weak antimicrobial activity against the tested strains with inhibitions zones ranging from 9 to 13 mm. EPS could reduce the free radical (DPPH) to diphenylpicrylhydrazine a yellow-colored at 24.25% showing antioxidant activity less than that of ascorbic acid which was 69.79%.
Abstract: The in vitro antimicrobial and antioxidant activities of the exopolysaccharide (EPS) extracted from yoghurt starter were investigated. Antimicrobial activity tests were carried out using disc diffusion methods with Escherichia coli, Staphylococcus aureus and Streptococcus D, Proteus spp and the yeast of Candida albicans. The antioxidant properties ...
Show More
An Overview of the Phytochemical Analysis of Bioactive Compounds in Senna alata
Funmilayo Adelowo,
Oluwole Oladeji
Issue:
Volume 5, Issue 5, October 2017
Pages:
102-109
Received:
10 September 2016
Accepted:
13 January 2017
Published:
18 October 2017
Abstract: The major problem man is facing is the growing rate of the activities of microbes. Virtually everything that surrounds man, even his environment are contaminated and polluted with these microbes. The use of medicinal plants for the treatment of bacteria and fungi that caused related diseases gave rise to the introduction of antibiotics or natural drugs. To promote the proper use of Senna alata as herbal medicine, their curative and therapeutic effects should be studied. Therefore, it is of great importance to determine the chemical components (phytochemicals) and the ethnobiological view of Senna alata extracts. This review presents updated information regarding the phytopharmacological profile of the plant.
Abstract: The major problem man is facing is the growing rate of the activities of microbes. Virtually everything that surrounds man, even his environment are contaminated and polluted with these microbes. The use of medicinal plants for the treatment of bacteria and fungi that caused related diseases gave rise to the introduction of antibiotics or natural d...
Show More
